ATE476449T1 - Verwendung von endosialinbindenden proteinen zum isolieren endosialinpositiver zellen - Google Patents
Verwendung von endosialinbindenden proteinen zum isolieren endosialinpositiver zellenInfo
- Publication number
- ATE476449T1 ATE476449T1 AT05847825T AT05847825T ATE476449T1 AT E476449 T1 ATE476449 T1 AT E476449T1 AT 05847825 T AT05847825 T AT 05847825T AT 05847825 T AT05847825 T AT 05847825T AT E476449 T1 ATE476449 T1 AT E476449T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- endosial
- monoclonal antibodies
- inpositive
- isolate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/515—Angiogenesic factors; Angiogenin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63306004P | 2004-12-03 | 2004-12-03 | |
| PCT/US2005/043749 WO2006060719A2 (en) | 2004-12-03 | 2005-12-02 | Use of endosialin binding proteins to isolate endosialin positive cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476449T1 true ATE476449T1 (de) | 2010-08-15 |
Family
ID=36565803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05847825T ATE476449T1 (de) | 2004-12-03 | 2005-12-02 | Verwendung von endosialinbindenden proteinen zum isolieren endosialinpositiver zellen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060121541A1 (de) |
| EP (1) | EP1819736B1 (de) |
| AT (1) | ATE476449T1 (de) |
| AU (1) | AU2005311660B2 (de) |
| CA (1) | CA2590583A1 (de) |
| DE (1) | DE602005022757D1 (de) |
| WO (1) | WO2006060719A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1871809A2 (de) | 2005-04-22 | 2008-01-02 | Morphotek, Inc. | Antikörper mit immuneffektor aktivität die in endosialin positive zellen internalisieren |
| CA2682726C (en) | 2007-04-05 | 2017-05-09 | Morphotek, Inc. | Methods for inhibiting the binding of endosialin to ligands |
| WO2010118203A2 (en) * | 2009-04-09 | 2010-10-14 | Morphotek, Inc. | Endosialin binding molecules |
| JP2013543379A (ja) * | 2010-09-29 | 2013-12-05 | モルフォテック， インコーポレイテッド | 操作されたヒトエンドシアリン発現齧歯動物 |
| DE102017125150B4 (de) | 2017-10-26 | 2019-10-10 | Epiontis Gmbh | Endosialin (CD248) als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere naïver CD8+ T-Zellen |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US121541A (en) * | 1871-12-05 | Improvement in folding plant-stands | ||
| US248034A (en) * | 1881-10-11 | gibbs | ||
| US20271A (en) * | 1858-05-18 | Improvement in harvesters | ||
| US239911A (en) * | 1881-04-05 | Parasol | ||
| US5789650A (en) * | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5342757A (en) * | 1992-11-13 | 1994-08-30 | Ludwig Institute For Cancer Research | Monoclonal antibodies which specifically binds to endosialin, a 165 Kd glycoprotein found on tumor vascular endothelium, and uses thereof |
| EP0686260B1 (de) * | 1993-02-05 | 2003-07-09 | Epigen, Inc. | Humanes carcinoma-antigen (hca), hca antikörper, hca immunoassays, aufzeichnungsmethoden und therapy |
| DE69535002T2 (de) * | 1994-03-08 | 2006-12-07 | Memorial Sloan-Kettering Cancer Center | Rekombinante humanisierte antikörper gegen fb5 |
| DE19541844C1 (de) * | 1995-11-09 | 1997-07-24 | Gsf Forschungszentrum Umwelt | Verfahren zur Herstellung von menschlichen Antikörpern und deren Verwendung |
| US6146894A (en) * | 1998-04-14 | 2000-11-14 | The Johns Hopkins University | Method for generating hypermutable organisms |
| EP2264073A1 (de) * | 2003-03-04 | 2010-12-22 | Kirin Beer Kabushiki Kaisha | Endothelzell-spezifische Antikörper und ihre Verwendung |
| US6905082B1 (en) * | 2003-12-05 | 2005-06-14 | Sheng Li Wu | Sprayer device having buffering structure |
| WO2005086713A2 (en) * | 2004-03-04 | 2005-09-22 | Kirin Brewery Co., Ltd. | Role of human endothelial precursor cells and vascular pericytes tumor in angiogenesis |
| EP1871809A2 (de) * | 2005-04-22 | 2008-01-02 | Morphotek, Inc. | Antikörper mit immuneffektor aktivität die in endosialin positive zellen internalisieren |
-
2005
- 2005-12-02 EP EP05847825A patent/EP1819736B1/de not_active Expired - Lifetime
- 2005-12-02 US US11/292,634 patent/US20060121541A1/en not_active Abandoned
- 2005-12-02 AT AT05847825T patent/ATE476449T1/de not_active IP Right Cessation
- 2005-12-02 AU AU2005311660A patent/AU2005311660B2/en not_active Ceased
- 2005-12-02 CA CA002590583A patent/CA2590583A1/en not_active Abandoned
- 2005-12-02 DE DE602005022757T patent/DE602005022757D1/de not_active Expired - Lifetime
- 2005-12-02 WO PCT/US2005/043749 patent/WO2006060719A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2590583A1 (en) | 2006-06-08 |
| WO2006060719A3 (en) | 2006-11-23 |
| WO2006060719A2 (en) | 2006-06-08 |
| EP1819736A2 (de) | 2007-08-22 |
| AU2005311660B2 (en) | 2011-07-07 |
| US20060121541A1 (en) | 2006-06-08 |
| DE602005022757D1 (de) | 2010-09-16 |
| EP1819736B1 (de) | 2010-08-04 |
| AU2005311660A1 (en) | 2006-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |