ATE476965T1 - Sterol-angereicherte multilamellare amphotericin- enthaltende liposomen in kochsalzlösung und herstellungsverfahren - Google Patents
Sterol-angereicherte multilamellare amphotericin- enthaltende liposomen in kochsalzlösung und herstellungsverfahrenInfo
- Publication number
- ATE476965T1 ATE476965T1 AT05759293T AT05759293T ATE476965T1 AT E476965 T1 ATE476965 T1 AT E476965T1 AT 05759293 T AT05759293 T AT 05759293T AT 05759293 T AT05759293 T AT 05759293T AT E476965 T1 ATE476965 T1 AT E476965T1
- Authority
- AT
- Austria
- Prior art keywords
- amphotericin
- sterol
- multilamellar
- enriched
- production method
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229930183010 Amphotericin Natural products 0.000 abstract 1
- QGGFZZLFKABGNL-UHFFFAOYSA-N Amphotericin A Natural products OC1C(N)C(O)C(C)OC1OC1C=CC=CC=CC=CCCC=CC=CC(C)C(O)C(C)C(C)OC(=O)CC(O)CC(O)CCC(O)C(O)CC(O)CC(O)(CC(O)C2C(O)=O)OC2C1 QGGFZZLFKABGNL-UHFFFAOYSA-N 0.000 abstract 1
- 208000030852 Parasitic disease Diseases 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- 229940009444 amphotericin Drugs 0.000 abstract 1
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000009830 intercalation Methods 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 244000000040 protozoan parasite Species 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 238000000527 sonication Methods 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1113DE2004 | 2004-06-11 | ||
| PCT/IN2005/000193 WO2005120460A1 (en) | 2004-06-11 | 2005-06-13 | Sterol enriched mixed lammelarity amphotericin intercalating liposomes in saline and the process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476965T1 true ATE476965T1 (de) | 2010-08-15 |
Family
ID=34972096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05759293T ATE476965T1 (de) | 2004-06-11 | 2005-06-13 | Sterol-angereicherte multilamellare amphotericin- enthaltende liposomen in kochsalzlösung und herstellungsverfahren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070218119A1 (de) |
| EP (1) | EP1771156B8 (de) |
| JP (1) | JP4966855B2 (de) |
| CN (1) | CN101014322A (de) |
| AT (1) | ATE476965T1 (de) |
| AU (1) | AU2005251572B2 (de) |
| BR (1) | BRPI0511371A (de) |
| DE (1) | DE602005022876D1 (de) |
| WO (1) | WO2005120460A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2488160B1 (de) * | 2009-10-16 | 2020-07-01 | Lifecare Innovations Pvt. Ltd. | Amphotericin-liposomenformulierung, umfassend cholesterin für die bekämpfung von pilzinfektionen |
| WO2017150705A1 (ja) * | 2016-03-04 | 2017-09-08 | 栗田工業株式会社 | 選択性透過膜及びその製造方法、該選択性透過膜を用いる水処理方法 |
| FI3694526T3 (fi) | 2017-10-11 | 2025-02-06 | Univ Illinois | Genotyypistä riippumaton toimintakyvyn palautus pienimolekyylisillä bikarbonaattikanavilla kystistä fibroosia varten |
| IL315719A (en) | 2022-03-21 | 2024-11-01 | Univ Illinois | Prosthetic assemblies of ion channels containing lipid-coated amphotericin B crystals |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2134869A (en) * | 1983-02-15 | 1984-08-22 | Squibb & Sons Inc | Method of preparing liposomes and products produced thereby |
| US4744989A (en) * | 1984-02-08 | 1988-05-17 | E. R. Squibb & Sons, Inc. | Method of preparing liposomes and products produced thereby |
| US4766046A (en) * | 1985-09-27 | 1988-08-23 | Liposome Technology, Inc. | Stabilized liposome/amphotericin composition and method |
-
2005
- 2005-06-13 AT AT05759293T patent/ATE476965T1/de not_active IP Right Cessation
- 2005-06-13 CN CNA200580023366XA patent/CN101014322A/zh active Pending
- 2005-06-13 DE DE602005022876T patent/DE602005022876D1/de not_active Expired - Lifetime
- 2005-06-13 US US11/570,379 patent/US20070218119A1/en not_active Abandoned
- 2005-06-13 WO PCT/IN2005/000193 patent/WO2005120460A1/en not_active Ceased
- 2005-06-13 EP EP05759293A patent/EP1771156B8/de not_active Expired - Lifetime
- 2005-06-13 JP JP2007526704A patent/JP4966855B2/ja not_active Expired - Fee Related
- 2005-06-13 AU AU2005251572A patent/AU2005251572B2/en not_active Ceased
- 2005-06-13 BR BRPI0511371-7A patent/BRPI0511371A/pt active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005022876D1 (de) | 2010-09-23 |
| WO2005120460A1 (en) | 2005-12-22 |
| EP1771156B8 (de) | 2010-09-15 |
| JP4966855B2 (ja) | 2012-07-04 |
| AU2005251572B2 (en) | 2010-03-11 |
| AU2005251572A1 (en) | 2005-12-22 |
| EP1771156B1 (de) | 2010-08-11 |
| BRPI0511371A (pt) | 2008-03-11 |
| US20070218119A1 (en) | 2007-09-20 |
| JP2008501782A (ja) | 2008-01-24 |
| EP1771156A1 (de) | 2007-04-11 |
| CN101014322A (zh) | 2007-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |