ATE476980T1 - Acylderivate des 4-demethylpenclomedins, verwendung und zubereitung derselben - Google Patents
Acylderivate des 4-demethylpenclomedins, verwendung und zubereitung derselbenInfo
- Publication number
- ATE476980T1 ATE476980T1 AT00904441T AT00904441T ATE476980T1 AT E476980 T1 ATE476980 T1 AT E476980T1 AT 00904441 T AT00904441 T AT 00904441T AT 00904441 T AT00904441 T AT 00904441T AT E476980 T1 ATE476980 T1 AT E476980T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- demethylpenclomedine
- acyl derivatives
- useful
- compounds
- Prior art date
Links
- GUYGGZGIKZIRFO-UHFFFAOYSA-N 3,5-dichloro-2-methoxy-6-(trichloromethyl)-1h-pyridin-4-one Chemical class COC=1NC(C(Cl)(Cl)Cl)=C(Cl)C(=O)C=1Cl GUYGGZGIKZIRFO-UHFFFAOYSA-N 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11667599P | 1999-01-21 | 1999-01-21 | |
| PCT/US2000/001347 WO2000043010A1 (en) | 1999-01-21 | 2000-01-21 | Acyl derivatives of 4-demethylpenclomedine, use thereof and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476980T1 true ATE476980T1 (de) | 2010-08-15 |
Family
ID=22368571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00904441T ATE476980T1 (de) | 1999-01-21 | 2000-01-21 | Acylderivate des 4-demethylpenclomedins, verwendung und zubereitung derselben |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6376518B1 (de) |
| EP (1) | EP1150676B1 (de) |
| JP (1) | JP4709387B2 (de) |
| AT (1) | ATE476980T1 (de) |
| AU (1) | AU2620100A (de) |
| DE (1) | DE60044804D1 (de) |
| ES (1) | ES2348973T3 (de) |
| HK (1) | HK1041648B (de) |
| PT (1) | PT1150676E (de) |
| WO (1) | WO2000043010A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1150676E (pt) | 1999-01-21 | 2010-11-09 | Southern Res Inst | Derivados acilo de 4-desmetilpenclomedina, sua utilização e sua preparação |
| WO2000043009A1 (en) * | 1999-01-21 | 2000-07-27 | Southern Research Institute | Pyridine compounds, use and preparation thereof |
| US20040214499A1 (en) * | 2003-04-25 | 2004-10-28 | Kimberly-Clark Worldwide, Inc. | Absorbent structure with superabsorbent material |
| US7122563B2 (en) * | 2005-02-01 | 2006-10-17 | Southern Research Institute | Derivatives of 4-demethylpenclomedine, use thereof and preparation thereof |
| US8124596B2 (en) * | 2005-12-13 | 2012-02-28 | Dekk-Tec, Inc. | Demethylpenclomedine analogs and their use as anti-cancer agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190662A (en) * | 1978-03-23 | 1980-02-26 | The Dow Chemical Company | Halomethyl substituted dialkoxypyridines |
| US4717726A (en) | 1986-09-10 | 1988-01-05 | The Dow Chemical Company | 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine having anti-tumor activity |
| AU3294097A (en) * | 1996-06-03 | 1998-01-05 | Johns Hopkins University School Of Medicine, The | Pyridine derivative, composition and method for treating cancer |
| PT1150676E (pt) | 1999-01-21 | 2010-11-09 | Southern Res Inst | Derivados acilo de 4-desmetilpenclomedina, sua utilização e sua preparação |
| WO2000043009A1 (en) * | 1999-01-21 | 2000-07-27 | Southern Research Institute | Pyridine compounds, use and preparation thereof |
-
2000
- 2000-01-21 PT PT00904441T patent/PT1150676E/pt unknown
- 2000-01-21 DE DE60044804T patent/DE60044804D1/de not_active Expired - Lifetime
- 2000-01-21 HK HK02103423.9A patent/HK1041648B/en not_active IP Right Cessation
- 2000-01-21 US US09/488,683 patent/US6376518B1/en not_active Expired - Lifetime
- 2000-01-21 ES ES00904441T patent/ES2348973T3/es not_active Expired - Lifetime
- 2000-01-21 AT AT00904441T patent/ATE476980T1/de active
- 2000-01-21 WO PCT/US2000/001347 patent/WO2000043010A1/en not_active Ceased
- 2000-01-21 AU AU26201/00A patent/AU2620100A/en not_active Abandoned
- 2000-01-21 JP JP2000594464A patent/JP4709387B2/ja not_active Expired - Fee Related
- 2000-01-21 US US09/488,684 patent/US6391893B1/en not_active Expired - Lifetime
- 2000-01-21 EP EP00904441A patent/EP1150676B1/de not_active Expired - Lifetime
-
2002
- 2002-03-25 US US10/103,869 patent/US6495571B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HK1041648B (en) | 2011-01-14 |
| PT1150676E (pt) | 2010-11-09 |
| WO2000043010A1 (en) | 2000-07-27 |
| US6495571B1 (en) | 2002-12-17 |
| ES2348973T3 (es) | 2010-12-20 |
| EP1150676A4 (de) | 2003-01-08 |
| EP1150676B1 (de) | 2010-08-11 |
| JP2002535276A (ja) | 2002-10-22 |
| US6391893B1 (en) | 2002-05-21 |
| HK1041648A1 (en) | 2002-07-19 |
| DE60044804D1 (de) | 2010-09-23 |
| EP1150676A1 (de) | 2001-11-07 |
| US6376518B1 (en) | 2002-04-23 |
| AU2620100A (en) | 2000-08-07 |
| JP4709387B2 (ja) | 2011-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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