ATE478602T1 - Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen - Google Patents

Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen

Info

Publication number: ATE478602T1
Authority: AT; Austria
Prior art keywords: protein; receptor; precursor; polypeptide; alpha
Prior art date: 2004-12-15

Application number

AT05858653T

Other languages

English (en)

Inventor

S Karumanchi

Vikas Sukhatme

Original Assignee

Beth Israel Hospital

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-12-15

Filing date

2005-12-15

Publication date

2010-09-15

2005-12-15 Application filed by Beth Israel Hospital filed Critical Beth Israel Hospital

2010-09-15 Application granted granted Critical

2010-09-15 Publication of ATE478602T1 publication Critical patent/ATE478602T1/de

Links

229920001184 polypeptide Polymers 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
102000039446 nucleic acids Human genes 0.000 title abstract 2
108020004707 nucleic acids Proteins 0.000 title abstract 2
150000007523 nucleic acids Chemical class 0.000 title abstract 2
208000002787 Pregnancy Complications Diseases 0.000 title 1
238000003745 diagnosis Methods 0.000 title 1
208000012113 pregnancy disease Diseases 0.000 title 1
239000002243 precursor Substances 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000005962 receptors Human genes 0.000 abstract 2
108020003175 receptors Proteins 0.000 abstract 2
102000008490 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine Human genes 0.000 abstract 1
108010020504 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine Proteins 0.000 abstract 1
102100030310 5,6-dihydroxyindole-2-carboxylic acid oxidase Human genes 0.000 abstract 1
102100027401 A disintegrin and metalloproteinase with thrombospondin motifs 3 Human genes 0.000 abstract 1
102100022524 Alpha-1-antichymotrypsin Human genes 0.000 abstract 1
102100022987 Angiogenin Human genes 0.000 abstract 1
102100030009 Azurocidin Human genes 0.000 abstract 1
101710154607 Azurocidin Proteins 0.000 abstract 1
102000019034 Chemokines Human genes 0.000 abstract 1
108010012236 Chemokines Proteins 0.000 abstract 1
102100032165 Corticotropin-releasing factor-binding protein Human genes 0.000 abstract 1
102100032522 Cyclin-dependent kinases regulatory subunit 2 Human genes 0.000 abstract 1
108010037778 Cytochrome P450 Family 11 Proteins 0.000 abstract 1
102100038493 Cytokine receptor-like factor 1 Human genes 0.000 abstract 1
101710194728 Cytokine receptor-like factor 1 Proteins 0.000 abstract 1
108010041308 Endothelial Growth Factors Proteins 0.000 abstract 1
102000001133 Fertilins Human genes 0.000 abstract 1
108010069446 Fertilins Proteins 0.000 abstract 1
102100029379 Follistatin-related protein 3 Human genes 0.000 abstract 1
108010001517 Galectin 3 Proteins 0.000 abstract 1
102100039558 Galectin-3 Human genes 0.000 abstract 1
101000936395 Homo sapiens A disintegrin and metalloproteinase with thrombospondin motifs 3 Proteins 0.000 abstract 1
101000942317 Homo sapiens Cyclin-dependent kinases regulatory subunit 2 Proteins 0.000 abstract 1
101001062529 Homo sapiens Follistatin-related protein 3 Proteins 0.000 abstract 1
101001054732 Homo sapiens Inhibin beta A chain Proteins 0.000 abstract 1
101000863880 Homo sapiens Sialic acid-binding Ig-like lectin 6 Proteins 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
102100027004 Inhibin beta A chain Human genes 0.000 abstract 1
108090000961 Insulin-like growth factor binding protein 5 Proteins 0.000 abstract 1
102000004371 Insulin-like growth factor binding protein 5 Human genes 0.000 abstract 1
102000014150 Interferons Human genes 0.000 abstract 1
108010050904 Interferons Proteins 0.000 abstract 1
102000003815 Interleukin-11 Human genes 0.000 abstract 1
108090000177 Interleukin-11 Proteins 0.000 abstract 1
102000004890 Interleukin-8 Human genes 0.000 abstract 1
108090001007 Interleukin-8 Proteins 0.000 abstract 1
102100032011 Lanosterol synthase Human genes 0.000 abstract 1
108010059597 Lanosterol synthase Proteins 0.000 abstract 1
102000003729 Neprilysin Human genes 0.000 abstract 1
108090000028 Neprilysin Proteins 0.000 abstract 1
102000004316 Oxidoreductases Human genes 0.000 abstract 1
108090000854 Oxidoreductases Proteins 0.000 abstract 1
102100031166 Peripheral plasma membrane protein CASK Human genes 0.000 abstract 1
101710112366 Peripheral plasma membrane protein CASK Proteins 0.000 abstract 1
102000001708 Protein Isoforms Human genes 0.000 abstract 1
108010029485 Protein Isoforms Proteins 0.000 abstract 1
102000004278 Receptor Protein-Tyrosine Kinases Human genes 0.000 abstract 1
108090000873 Receptor Protein-Tyrosine Kinases Proteins 0.000 abstract 1
102100030053 Secreted frizzled-related protein 3 Human genes 0.000 abstract 1
102100029947 Sialic acid-binding Ig-like lectin 6 Human genes 0.000 abstract 1
210000001744 T-lymphocyte Anatomy 0.000 abstract 1
101710172645 UDP-glycosyltransferase 2 Proteins 0.000 abstract 1
108010073923 Vascular Endothelial Growth Factor C Proteins 0.000 abstract 1
102000009520 Vascular Endothelial Growth Factor C Human genes 0.000 abstract 1
108010020277 WD repeat containing planar cell polarity effector Proteins 0.000 abstract 1
108010091628 alpha 1-Antichymotrypsin Proteins 0.000 abstract 1
102000018568 alpha-Defensin Human genes 0.000 abstract 1
108050007802 alpha-defensin Proteins 0.000 abstract 1
108010072788 angiogenin Proteins 0.000 abstract 1
102000006995 beta-Glucosidase Human genes 0.000 abstract 1
108010047754 beta-Glucosidase Proteins 0.000 abstract 1
239000002975 chemoattractant Substances 0.000 abstract 1
108010083720 corticotropin releasing factor-binding protein Proteins 0.000 abstract 1
229940011871 estrogen Drugs 0.000 abstract 1
239000000262 estrogen Substances 0.000 abstract 1
102000040409 glycosyltransferase 2 family Human genes 0.000 abstract 1
108010067471 inhibin A Proteins 0.000 abstract 1
229940079322 interferon Drugs 0.000 abstract 1
229940096397 interleukin-8 Drugs 0.000 abstract 1
XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 abstract 1
210000000265 leukocyte Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000000508 neurotrophic effect Effects 0.000 abstract 1
230000035935 pregnancy Effects 0.000 abstract 1
108010051421 procholecystokinin Proteins 0.000 abstract 1
108010052178 teleocalcin Proteins 0.000 abstract 1
108010014402 tyrosinase-related protein-1 Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Analytical Chemistry (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Pathology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Cell Biology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Reproductive Health (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT05858653T 2004-12-15 2005-12-15 Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen ATE478602T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US63627504P	2004-12-15	2004-12-15
PCT/US2005/045805 WO2007053161A2 (en)	2004-12-15	2005-12-15	Nucleic acids and polypeptides useful for diagnosing and treating complications of pregnancy

Publications (1)

Publication Number	Publication Date
ATE478602T1 true ATE478602T1 (de)	2010-09-15

Family

ID=38006337

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05858653T ATE478602T1 (de)	2004-12-15	2005-12-15	Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen

Country Status (11)

Country	Link
US (1)	US7955805B2 (de)
EP (1)	EP1839057B1 (de)
JP (1)	JP2008523816A (de)
KR (1)	KR20070092737A (de)
CN (1)	CN101299962A (de)
AT (1)	ATE478602T1 (de)
AU (1)	AU2005337873A1 (de)
BR (1)	BRPI0519096A2 (de)
CA (1)	CA2591142A1 (de)
DE (1)	DE602005023216D1 (de)
WO (1)	WO2007053161A2 (de)

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DE10333105B3 (de) *	2003-07-21	2005-05-25	OCé PRINTING SYSTEMS GMBH	Einrichtung zur Einstellung der Spannung einer Materialbahn, die durch eine die Materialbahn bearbeitende Prozessstation bewegt wird
US7323346B2 (en) *	2003-08-14	2008-01-29	The General Hospital Corporation	Screening for gestational disorders
ES2556164T3 (es) *	2003-09-23	2016-01-13	The General Hospital Corporation	Cribado de la preeclampsia
WO2006034507A2 (en) *	2004-09-24	2006-03-30	Beth Israel - Deaconess Medical Center	Methods of diagnosing and treating complications of pregnancy
US7740849B2 (en) *	2004-09-24	2010-06-22	Beth Israel Deaconess Medical Center	Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders
ATE519109T1 (de) *	2004-12-21	2011-08-15	Univ Yale	Präeklampsie-diagnose
CN101517078A (zh)	2006-05-31	2009-08-26	貝丝以色列女执事医疗中心	诊断和治疗妊娠并发症的方法

2005
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- 2005-12-15 JP JP2007546973A patent/JP2008523816A/ja active Pending
- 2005-12-15 DE DE602005023216T patent/DE602005023216D1/de not_active Expired - Lifetime
- 2005-12-15 KR KR1020077016078A patent/KR20070092737A/ko not_active Withdrawn
- 2005-12-15 CA CA002591142A patent/CA2591142A1/en not_active Abandoned
- 2005-12-15 CN CNA2005800483839A patent/CN101299962A/zh active Pending
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Publication number	Publication date
EP1839057A4 (de)	2008-12-31
EP1839057A2 (de)	2007-10-03
AU2005337873A1 (en)	2007-05-10
CN101299962A (zh)	2008-11-05
US20060166277A1 (en)	2006-07-27
DE602005023216D1 (de)	2010-10-07
KR20070092737A (ko)	2007-09-13
BRPI0519096A2 (pt)	2008-12-23
JP2008523816A (ja)	2008-07-10
CA2591142A1 (en)	2007-05-10
WO2007053161A2 (en)	2007-05-10
EP1839057B1 (de)	2010-08-25
WO2007053161A3 (en)	2007-11-29
HK1115286A1 (en)	2008-11-28
US7955805B2 (en)	2011-06-07

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2011-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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