ATE479770T1 - Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie - Google Patents
Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrieInfo
- Publication number
- ATE479770T1 ATE479770T1 AT07761533T AT07761533T ATE479770T1 AT E479770 T1 ATE479770 T1 AT E479770T1 AT 07761533 T AT07761533 T AT 07761533T AT 07761533 T AT07761533 T AT 07761533T AT E479770 T1 ATE479770 T1 AT E479770T1
- Authority
- AT
- Austria
- Prior art keywords
- deglycosylation
- proteins
- molecular weight
- mass spectrometry
- assisted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79733406P | 2006-05-02 | 2006-05-02 | |
| PCT/US2007/067714 WO2007130875A2 (en) | 2006-05-02 | 2007-04-27 | Microwave assisted deglycosylation of proteins for molecular weight determination by mass spectrometry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE479770T1 true ATE479770T1 (de) | 2010-09-15 |
Family
ID=38648516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07761533T ATE479770T1 (de) | 2006-05-02 | 2007-04-27 | Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8163518B2 (de) |
| EP (1) | EP2013356B1 (de) |
| JP (1) | JP5219998B2 (de) |
| AT (1) | ATE479770T1 (de) |
| AU (1) | AU2007248253B2 (de) |
| CA (1) | CA2650281C (de) |
| DE (1) | DE602007008872D1 (de) |
| WO (1) | WO2007130875A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011521255A (ja) * | 2008-07-23 | 2011-07-21 | インダストリー−アカデミック コーオペレーション ファンデーション キョンサン ナショナル ユニバーシティ | ウイルス診断方法及びシステム |
| PT3387898T (pt) * | 2013-03-15 | 2020-06-17 | Mayo Found Medical Education & Res | Identificação e monitorização de imunoglobulinas monoclonais pela massa molecular |
| EP3126826B1 (de) | 2014-04-04 | 2020-12-16 | Mayo Foundation for Medical Education and Research | Isotypisierung von immunglobulinen unter verwendung einer genauen molekülmasse |
| US10690676B2 (en) | 2014-07-29 | 2020-06-23 | Mayo Roundation for Medical Education and Research | Quantifying monoclonal antibody therapeutics by LC-MS/MS |
| EP3289364B1 (de) * | 2015-04-30 | 2019-09-18 | DH Technologies Development Pte. Ltd. | Identifizierung von glycosylierungsformen |
| WO2017053932A1 (en) | 2015-09-24 | 2017-03-30 | Mayo Foundation For Medical Education And Research | Identification of immunoglobulin free light chains by mass spectrometry |
| AU2017325022B2 (en) | 2016-09-07 | 2022-10-13 | Mayo Foundation For Medical Education And Research | Identification and monitoring of cleaved immunoglobulins by molecular mass |
| WO2019055634A1 (en) | 2017-09-13 | 2019-03-21 | Mayo Foundation For Medical Education And Research | IDENTIFICATION AND MONITORING OF A MACROPHAGE APOPTOSIS INHIBITOR |
| US12153052B2 (en) | 2017-09-13 | 2024-11-26 | Mayo Foundation For Medical Education And Research | Identification and monitoring of immunoglobulin J chains |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5350686A (en) * | 1992-04-16 | 1994-09-27 | Pioneer Hi-Bred International, Inc. | Microwave acceleration of enzyme-catalyzed modification of macromolecules |
| AUPN694895A0 (en) * | 1995-12-01 | 1996-01-04 | Macquarie Research Limited | Desalting and purification of oligosaccharides and their derivatives |
| GB9821198D0 (en) * | 1998-09-30 | 1998-11-25 | Danisco | Enzyme |
| US6960562B2 (en) * | 1999-04-23 | 2005-11-01 | Rhode Island Hospital, A Lifespan Partner | Tribonectin polypeptides and uses thereof |
| US20030059432A1 (en) * | 2000-02-11 | 2003-03-27 | Dillon Davin C. | Lipophilin complexes for use in cancer diagnosis and therapy |
| WO2002022808A2 (en) * | 2000-09-18 | 2002-03-21 | Biogen, Inc. | Cripto mutant and uses thereof |
| US6720165B2 (en) * | 2001-06-14 | 2004-04-13 | Zyomix, Inc. | Methods for making antibody fragments and compositions resulting therefrom |
| EP1406089A1 (de) * | 2002-10-02 | 2004-04-07 | Taiwan Unison Biotechnology Co. Ltd. | Eine Methode zur selektiven Färbung wasserlöslicher Proteine unter Verwendung von Reaktivfarbstoffen |
| CN1852765A (zh) * | 2002-10-18 | 2006-10-25 | 普罗梅加公司 | 用于分离分子的组合物 |
| EP1740954B1 (de) * | 2004-04-07 | 2015-08-19 | Genentech, Inc. | Massenspektrometrie von antikörperkonjugaten |
-
2007
- 2007-04-27 WO PCT/US2007/067714 patent/WO2007130875A2/en not_active Ceased
- 2007-04-27 DE DE602007008872T patent/DE602007008872D1/de active Active
- 2007-04-27 AT AT07761533T patent/ATE479770T1/de not_active IP Right Cessation
- 2007-04-27 CA CA2650281A patent/CA2650281C/en active Active
- 2007-04-27 JP JP2009509978A patent/JP5219998B2/ja active Active
- 2007-04-27 AU AU2007248253A patent/AU2007248253B2/en active Active
- 2007-04-27 EP EP07761533A patent/EP2013356B1/de active Active
- 2007-04-27 US US11/741,490 patent/US8163518B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007130875A2 (en) | 2007-11-15 |
| AU2007248253A1 (en) | 2007-11-15 |
| WO2007130875A3 (en) | 2008-01-17 |
| JP2009535646A (ja) | 2009-10-01 |
| EP2013356A2 (de) | 2009-01-14 |
| US8163518B2 (en) | 2012-04-24 |
| EP2013356B1 (de) | 2010-09-01 |
| JP5219998B2 (ja) | 2013-06-26 |
| CA2650281C (en) | 2012-09-11 |
| AU2007248253B2 (en) | 2010-12-23 |
| CA2650281A1 (en) | 2007-11-15 |
| US20070259398A1 (en) | 2007-11-08 |
| DE602007008872D1 (de) | 2010-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE479770T1 (de) | Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie | |
| EA200802005A1 (ru) | Стабилизированная связывающая молекула на основе стабилизированной молекулы scfv (варианты) и варианты получения и использования вышеназванных стабилизированных молекул | |
| ATE515488T1 (de) | Click-chemie zur herstellung von reportermolekülen | |
| CY1121562T1 (el) | Anti-fxi αντισωματα και μεθοδοι χρησης | |
| WO2010132453A3 (en) | Methods and compositions for analyte detection | |
| EP1994142A4 (de) | Verfahren und zusammensetzungen zur schnellen isolierung kleiner rna-moleküle | |
| EA201100300A1 (ru) | Композиции и способы, предназначенные для направленного воздействия антител на белок c5 системы комплемента | |
| EP2200657A4 (de) | Verbesserte verfahren und zusammensetzungen zur f-18-markierung von proteinen, peptiden und anderen molekülen | |
| CL2008003784A1 (es) | Anticuerpo humanizado anti proteina e2 del virus de la hepatitis c o un fragmento de union; acido nucleico que lo codifica; vector y celula huesped que comprenden dicho acido nucleico; metodo para producir el anticuerpo; composicion farmaceutica que comprende el anticuerpo | |
| MX2018005512A (es) | Agentes de union de esclerostina. | |
| EA200801571A1 (ru) | Композиции, содержащие молекулы ctl4-ig, и способы их получения | |
| WO2011047087A3 (en) | Protein detection via nanoreporters | |
| DE602004025101D1 (de) | Humane anti-humane cd3-bindungsmoleküle | |
| TWI317811B (de) | ||
| DE602004025996D1 (de) | Immortalisierte Entezelllinien zur Viruserzeugung | |
| ATE472734T1 (de) | Direktbestimmung von vitamin d im serum oder plasma | |
| EP2336174B8 (de) | Humane monoklonale Antikörper gegen Hendra- und Nipah-Viren | |
| EA201171494A1 (ru) | Миметики белка smac | |
| WO2009048839A3 (en) | Vaccinia virus h3l and b5r specific monoclonal antibodies and methods of making and using same | |
| ATE514090T1 (de) | Verwendung des proteins satb2 als marker zur unterscheidung kolorektaler karzinome von anderen krebserkrankungen | |
| WO2019139980A8 (en) | Methods for measuring analyte and/or protein in biological samples | |
| WO2006101387A3 (en) | Method for interfering with blood coagulation by modulating cross-beta structures fibril formation | |
| BRPI0815460A2 (pt) | kit de diagnóstico ou dispositivo e método para prognóstico de cancro em sujeitos mamíferos | |
| DE602005027399D1 (de) | Für humane matriptase spezifische bindungsproteine | |
| EA200801174A1 (ru) | Антитела-миметики glp-2, полипептиды, композиции, способы и применения |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |