ATE481973T1 - METHOD FOR TREATING ACUTE VASCULAR DISEASE - Google Patents

METHOD FOR TREATING ACUTE VASCULAR DISEASE

Info

Publication number
ATE481973T1
ATE481973T1 AT07709154T AT07709154T ATE481973T1 AT E481973 T1 ATE481973 T1 AT E481973T1 AT 07709154 T AT07709154 T AT 07709154T AT 07709154 T AT07709154 T AT 07709154T AT E481973 T1 ATE481973 T1 AT E481973T1
Authority
AT
Austria
Prior art keywords
mammal
acute vascular
vascular disease
treating acute
steroid
Prior art date
Application number
AT07709154T
Other languages
German (de)
Inventor
Herman Jan Thijmen Coelingh Bennink
Original Assignee
Pantarhei Bioscience Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantarhei Bioscience Bv filed Critical Pantarhei Bioscience Bv
Priority claimed from PCT/NL2007/050006 external-priority patent/WO2007081206A1/en
Application granted granted Critical
Publication of ATE481973T1 publication Critical patent/ATE481973T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

The present invention relates to a method of treating an acute vascular disorder in a mammal, said method comprising orally administering to said mammal, upon demand, an effective amount of a steroid to said mammal, said steroid being selected from the group consisting of: substances represented by formula (I), in which R1, R2, R3, R4 independent ly are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R5, R6, R7 is a hydroxyl group; no more than 3 of R1, R2, R3, R4 are hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors.
AT07709154T 2006-01-09 2007-01-09 METHOD FOR TREATING ACUTE VASCULAR DISEASE ATE481973T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75702706P 2006-01-09 2006-01-09
EP06100159 2006-01-09
PCT/NL2007/050006 WO2007081206A1 (en) 2006-01-09 2007-01-09 A method of treating an acute vascular disorder

Publications (1)

Publication Number Publication Date
ATE481973T1 true ATE481973T1 (en) 2010-10-15

Family

ID=36100928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07709154T ATE481973T1 (en) 2006-01-09 2007-01-09 METHOD FOR TREATING ACUTE VASCULAR DISEASE

Country Status (4)

Country Link
CN (1) CN101378762A (en)
AT (1) ATE481973T1 (en)
DE (1) DE602007009358D1 (en)
ES (1) ES2352547T3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3701944T (en) 2015-06-18 2022-04-11 Estetra Srl ORAL DISPERSIBLE DOSAGE UNIT CONTAINING AN ESTETROL
ES2671160T3 (en) * 2015-06-18 2018-06-05 Mithra Pharmaceuticals S.A. Orodispersible dosing unit containing an estetrol component
KR102712911B1 (en) 2016-08-05 2024-10-04 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 Method for the management of dysmenorrhea and menstrual pain
TWI801561B (en) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 Compounds and their uses for alleviating menopause-associated symptoms
TWI893101B (en) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 Contraceptive compositions with reduced adverse effects

Also Published As

Publication number Publication date
CN101378762A (en) 2009-03-04
DE602007009358D1 (en) 2010-11-04
ES2352547T3 (en) 2011-02-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties