ATE482748T1 - Hemmung reaktiver sauerstoffspezies und schutz von säugerzellen - Google Patents
Hemmung reaktiver sauerstoffspezies und schutz von säugerzellenInfo
- Publication number
- ATE482748T1 ATE482748T1 AT06751658T AT06751658T ATE482748T1 AT E482748 T1 ATE482748 T1 AT E482748T1 AT 06751658 T AT06751658 T AT 06751658T AT 06751658 T AT06751658 T AT 06751658T AT E482748 T1 ATE482748 T1 AT E482748T1
- Authority
- AT
- Austria
- Prior art keywords
- oxygen species
- reactive oxygen
- ros
- protection
- vitro
- Prior art date
Links
- 239000003642 reactive oxygen metabolite Substances 0.000 title abstract 9
- 241000124008 Mammalia Species 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 229910000420 cerium oxide Inorganic materials 0.000 abstract 3
- 238000000338 in vitro Methods 0.000 abstract 3
- 238000001727 in vivo Methods 0.000 abstract 3
- BMMGVYCKOGBVEV-UHFFFAOYSA-N oxo(oxoceriooxy)cerium Chemical compound [Ce]=O.O=[Ce]=O BMMGVYCKOGBVEV-UHFFFAOYSA-N 0.000 abstract 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 206010064930 age-related macular degeneration Diseases 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 208000002780 macular degeneration Diseases 0.000 abstract 2
- 210000004962 mammalian cell Anatomy 0.000 abstract 2
- 230000007512 neuronal protection Effects 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 230000002207 retinal effect Effects 0.000 abstract 2
- 210000001116 retinal neuron Anatomy 0.000 abstract 2
- 201000007737 Retinal degeneration Diseases 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 210000001525 retina Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67604305P | 2005-04-29 | 2005-04-29 | |
| US71663005P | 2005-09-13 | 2005-09-13 | |
| PCT/US2006/016050 WO2006118954A2 (en) | 2005-04-29 | 2006-04-27 | Inhibition of reactive oxygen species and protection of mammalian cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482748T1 true ATE482748T1 (de) | 2010-10-15 |
Family
ID=37308499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06751658T ATE482748T1 (de) | 2005-04-29 | 2006-04-27 | Hemmung reaktiver sauerstoffspezies und schutz von säugerzellen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7727559B2 (de) |
| EP (2) | EP1879570B1 (de) |
| AT (1) | ATE482748T1 (de) |
| AU (1) | AU2006242541B2 (de) |
| CA (1) | CA2610296C (de) |
| DE (1) | DE602006017199D1 (de) |
| WO (1) | WO2006118954A2 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110111007A1 (en) * | 2005-04-29 | 2011-05-12 | Mcginnis James F | Inhibition of retinal cell degeneration or neovascularization by cerium oxide nanoparticles |
| US10857178B2 (en) * | 2005-06-27 | 2020-12-08 | Edward Via Virginia College Of Osteopathic Medicine | Cerium oxide nanoparticles for treatment and prevention of Alzheimer's disease, Parkinson's disease, and disorders associated with free radical production and/or mitochondrial dysfunction |
| WO2007002662A2 (en) * | 2005-06-27 | 2007-01-04 | Edward Via Virginia College Of Osteopathic Medicine | Anti-inflammatory, radioprotective, and longevity enhancing capabilities of cerium oxide nanoparticles |
| US9649337B2 (en) | 2005-06-27 | 2017-05-16 | Edward Via Virginia College Of Osteopathic Medicine | Cerium oxide nanoparticles for the treatment and prevention of stroke and cardiovascular disease |
| US7959949B2 (en) | 2006-04-27 | 2011-06-14 | University Of Central Florida Research Foundation, Inc. | Functionalized nanoceria composition for ophthalmic treatment |
| WO2008064357A2 (en) * | 2006-11-22 | 2008-05-29 | University Of Florida Research Foundation, Inc. | Nanoparticles for protection of cells from oxidative stress |
| WO2008083401A1 (en) | 2007-01-02 | 2008-07-10 | University Of Central Florida Research Foundation Inc. | Methods and materials for stimulating proliferation of stem cells |
| US9119391B1 (en) | 2007-07-16 | 2015-09-01 | University Of Central Florida Research Foundation, Inc. | Polymer coated ceria nanoparticles for selective cytoprotection |
| US8916199B1 (en) | 2008-04-25 | 2014-12-23 | University of Central Florida Research Foundation, Ind. | Inhibition of angiogenesis associated with ovarian cancer by nanoparticles of cerium oxide |
| WO2009132277A1 (en) * | 2008-04-25 | 2009-10-29 | The Board Of Regents Of The University Of Oklahoma | Inhibition of neovascularization by cerium oxide nanoparticles |
| US9207385B2 (en) | 2008-05-06 | 2015-12-08 | Qd Vision, Inc. | Lighting systems and devices including same |
| WO2009151515A1 (en) | 2008-05-06 | 2009-12-17 | Qd Vision, Inc. | Solid state lighting devices including quantum confined semiconductor nanoparticles |
| US9127202B1 (en) | 2008-07-18 | 2015-09-08 | University Of Central Florida Research Foundation, Inc. | Biocompatible nano rare earth oxide upconverters for imaging and therapeutics |
| US20100098768A1 (en) * | 2008-10-16 | 2010-04-22 | Clarkson University | Method of neuroprotection from oxidant injury using metal oxide nanoparticles |
| US8883519B1 (en) | 2009-03-17 | 2014-11-11 | University Of Central Florida Research Foundation, Inc. | Oxidase activity of polymeric coated cerium oxide nanoparticles |
| WO2010129350A2 (en) | 2009-04-28 | 2010-11-11 | Qd Vision, Inc. | Optical materials, optical, components, devices, and methods |
| US9585840B1 (en) | 2009-07-10 | 2017-03-07 | University Of Central Florida Research Foundation, Inc. | Redox active cerium oxide nanoparticles and associated methods |
| US8795731B1 (en) | 2009-10-12 | 2014-08-05 | University Of Central Florida Research Foundation, Inc. | Cerium oxide nanoparticle-based device for the detection of reactive oxygen species and monitoring of chronic inflammation |
| WO2012036786A1 (en) | 2010-09-17 | 2012-03-22 | University Of L'aquila | Nanoparticles of cerium oxide targeted to an amyloid-beta antigen of alzheimer's disease |
| US11116792B1 (en) | 2010-12-22 | 2021-09-14 | Biocurity Holdings, Inc. | Cerium oxide nanoparticle formulation for use in skin radioprotection and associated methods |
| US8951539B1 (en) | 2011-06-07 | 2015-02-10 | University Of Central Florida Research Foundation, Inc. | Methods of promoting angiogenesis using cerium oxide nanoparticles |
| US9161950B2 (en) | 2011-09-21 | 2015-10-20 | University Of Central Florida Foundation, Inc. | Neuronal protection by cerium oxide nanoparticles |
| CA2869554A1 (en) | 2012-04-04 | 2013-10-10 | Duke University | Methods of using cerium oxide nanoparticles to mitigate or protect against radiation injury |
| US9463437B2 (en) | 2013-02-14 | 2016-10-11 | University Of Central Florida Research Foundation, Inc. | Methods for scavenging nitric oxide using cerium oxide nanoparticles |
| US9669055B1 (en) | 2014-04-11 | 2017-06-06 | Marshall University Research Corporation | Methods for treating sepsis |
| US11389536B2 (en) | 2015-07-17 | 2022-07-19 | BioCurity Pharmaceuticals Inc. | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent |
| CN108685847A (zh) * | 2018-06-29 | 2018-10-23 | 温州医科大学 | 一种针对氧化损伤诱导炎症的长效抗炎眼用分散制剂 |
| EP4074319A1 (de) | 2021-04-15 | 2022-10-19 | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca | Ophthalmische topische zusammensetzung mit ceroxid-nanoteilchen zur behandlung von erkrankungen des hinteren augensegments |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US676043A (en) | 1899-11-22 | 1901-06-11 | John C Lincoln | Electric drill. |
| US716630A (en) | 1902-03-24 | 1902-12-23 | August Eimer | Crucible. |
| AU5251999A (en) * | 1998-08-04 | 2000-02-28 | Wisconsin Alumni Research Foundation | Method of reducing retinal ganglion cell degeneration |
| EP1137395A1 (de) * | 1998-12-11 | 2001-10-04 | Cognis Deutschland GmbH | Verwendung von nanoskaligen organischen uv-lichtschutzfiltern |
| US7930285B2 (en) * | 2000-03-22 | 2011-04-19 | Comscore, Inc. | Systems for and methods of user demographic reporting usable for identifying users and collecting usage data |
| FR2809637B1 (fr) * | 2000-06-05 | 2003-01-24 | Rhodia Terres Rares | Dispersion colloidale d'un compose de cerium ou d'un compose de cerium et d'au moins un autre element choisi parmi les terres rares et des metaux de transition et comprenant un acide amine |
| EP1298159A4 (de) * | 2000-07-05 | 2004-03-31 | Nippon Arc Co Ltd | Transparentes mehrschichtmaterial, plastiklinse für brille und haftvermittlerzusammensetzung |
| US8097270B2 (en) * | 2001-12-21 | 2012-01-17 | Novartis Ag | Use of nanoparticles as carriers for biocides in ophthalmic compositions |
| KR101087763B1 (ko) * | 2002-10-28 | 2011-11-30 | 닛산 가가쿠 고교 가부시키 가이샤 | 산화 세륨 입자 및 그 제조방법 |
| WO2004096146A2 (en) * | 2003-04-25 | 2004-11-11 | Nolan Gerard M | Method and composition for preventing, reducing and reversing ocular ischemic neuronal damage |
-
2006
- 2006-04-27 EP EP06751658A patent/EP1879570B1/de not_active Expired - Lifetime
- 2006-04-27 AU AU2006242541A patent/AU2006242541B2/en not_active Ceased
- 2006-04-27 AT AT06751658T patent/ATE482748T1/de not_active IP Right Cessation
- 2006-04-27 WO PCT/US2006/016050 patent/WO2006118954A2/en not_active Ceased
- 2006-04-27 CA CA2610296A patent/CA2610296C/en not_active Expired - Fee Related
- 2006-04-27 EP EP10181322A patent/EP2359907A1/de not_active Withdrawn
- 2006-04-27 US US11/412,665 patent/US7727559B2/en not_active Expired - Lifetime
- 2006-04-27 DE DE602006017199T patent/DE602006017199D1/de not_active Expired - Lifetime
-
2007
- 2007-04-27 US US11/796,347 patent/US7347987B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20070202193A1 (en) | 2007-08-30 |
| EP2359907A1 (de) | 2011-08-24 |
| EP1879570B1 (de) | 2010-09-29 |
| US7347987B2 (en) | 2008-03-25 |
| DE602006017199D1 (de) | 2010-11-11 |
| WO2006118954A8 (en) | 2007-08-23 |
| EP1879570A2 (de) | 2008-01-23 |
| US20060246152A1 (en) | 2006-11-02 |
| US7727559B2 (en) | 2010-06-01 |
| WO2006118954A3 (en) | 2007-05-24 |
| WO2006118954A2 (en) | 2006-11-09 |
| CA2610296A1 (en) | 2006-11-09 |
| EP1879570A4 (de) | 2008-10-01 |
| CA2610296C (en) | 2016-06-14 |
| AU2006242541A1 (en) | 2006-11-09 |
| AU2006242541B2 (en) | 2011-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602006017199D1 (de) | Hemmung reaktiver sauerstoffspezies und schutz von säugerzellen | |
| Ishii | Functional singlet oxygen generators based on phthalocyanines | |
| He et al. | Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation | |
| Zholobak et al. | Panthenol-stabilized cerium dioxide nanoparticles for cosmeceutic formulations against ROS-induced and UV-induced damage | |
| Akhtar et al. | Glutathione replenishing potential of CeO2 nanoparticles in human breast and fibrosarcoma cells | |
| Monteiro et al. | Titanium dioxide nanotubes incorporated into bleaching agents: physicochemical characterization and enamel color change | |
| You et al. | Core-modified porphyrins. Part 4: Steric effects on photophysical and biological properties in vitro | |
| JP2020506953A5 (de) | ||
| ATE547107T1 (de) | Verwendung von selenhefe in der behandlung von alzheimers krankheit | |
| Johnson et al. | Reduced ischemia/reperfusion injury via glutathione-initiated nitric oxide-releasing dendrimers | |
| Zhang et al. | MnO2-capped silk fibroin (SF) nanoparticles with chlorin e6 (Ce6) encapsulation for augmented photo-driven therapy by modulating the tumor microenvironment | |
| Zhang et al. | Integrated two-phase free radical hydrogel: Safe, ultra-fast tooth whitening and antibacterial activity | |
| Zhu et al. | Introducing nanozymes: new horizons in periodontal and dental implant care | |
| Pradeep et al. | Exploring plant-derived carbon dots: Dual-functional nanomaterials for endodontic infections and enhanced bio-imaging | |
| Lv et al. | Enhanced photodynamic therapy through multienzyme-like MOF for cancer treatment | |
| Kato et al. | Fullerene-C60 derivatives prevent UV-irradiation/TiO2-induced cytotoxicity on keratinocytes and 3D-skin tissues through antioxidant actions | |
| Zhu et al. | Enhanced Xanthium‐Inspired ZnO for Precision Antibacterial Therapy and Regeneration of Infected Wounds | |
| Zhao et al. | Quantum dots enhance Cu2+-induced hepatic L02 cells toxicity | |
| Gravina et al. | Protective role against hydrogen peroxide and fibroblast stimulation via Ce-doped TiO2 nanostructured materials | |
| Huang et al. | Bimetallic H-Pt3Sn nanoparticles with photothermal enhanced dual enzyme-like activities for wound healing | |
| Abu-Taweel et al. | Yttrium oxide nanoparticles moderate the abnormal cognitive behaviors in male mice induced by silver nanoparticles | |
| Mahesh et al. | Highly efficient strategy for photocatalytic tooth bleaching using SiO2/MgO/Fe2O3 nanocomposite spheres | |
| Pugdee et al. | The viability of human dental pulp cells and apical papilla cells after treatment with conventional calcium hydroxide and nanoparticulate calcium hydroxide at various concentrations | |
| Li et al. | Microenvironment responsive biomineralization nanofirework employing H2S-assisted photothermal therapy to prompt bacterial wound healing | |
| Zhong et al. | Dual-functional isoquercitin‑silver nanoparticles alleviate bacterial-induced excessive inflammation of wound infection and sepsis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |