ATE482978T1 - Mimetische cd4-peptide und ihre verwendungen - Google Patents
Mimetische cd4-peptide und ihre verwendungenInfo
- Publication number
- ATE482978T1 ATE482978T1 AT07825126T AT07825126T ATE482978T1 AT E482978 T1 ATE482978 T1 AT E482978T1 AT 07825126 T AT07825126 T AT 07825126T AT 07825126 T AT07825126 T AT 07825126T AT E482978 T1 ATE482978 T1 AT E482978T1
- Authority
- AT
- Austria
- Prior art keywords
- cys
- leu
- arg
- xaad
- xaac
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 150000008574 D-amino acids Chemical class 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000036436 anti-hiv Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004404 heteroalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 150000002993 phenylalanine derivatives Chemical class 0.000 abstract 1
- KOODSCBKXPPKHE-UHFFFAOYSA-N propanethioic s-acid Chemical group CCC(S)=O KOODSCBKXPPKHE-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2006/002332 WO2007144685A1 (en) | 2006-06-13 | 2006-06-13 | Cd4 mimic peptides and their uses |
| PCT/IB2007/002686 WO2008010088A2 (en) | 2006-06-13 | 2007-05-09 | Cd4 mimic peptides and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE482978T1 true ATE482978T1 (de) | 2010-10-15 |
Family
ID=37714235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07825126T ATE482978T1 (de) | 2006-06-13 | 2007-05-09 | Mimetische cd4-peptide und ihre verwendungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8354498B2 (de) |
| EP (1) | EP2035453B1 (de) |
| CN (1) | CN101522710A (de) |
| AT (1) | ATE482978T1 (de) |
| DE (1) | DE602007009527D1 (de) |
| ES (1) | ES2371471T3 (de) |
| WO (2) | WO2007144685A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2904627B1 (fr) * | 2006-08-04 | 2008-11-07 | Pasteur Institut | Nouveaux peptides actives, purifies et isoles, derives du recepteur cd4 (mini-cd4) et leur procece de preparation |
| EP2087911A1 (de) * | 2008-02-06 | 2009-08-12 | Institut Pasteur | Konjugierte Moleküle mit einem Peptid aus dem mit einem Polyanion gekoppelten CD4-Rezeptor zur Behandlung von AIDS |
| US20130108653A1 (en) * | 2009-12-22 | 2013-05-02 | Shervin Bahrami | Bivalent molecules for hiv entry inhibition |
| EP2786766A1 (de) * | 2013-04-05 | 2014-10-08 | Ufpeptides S.r.l. | Supramolekulare Aggregate mit Maleimido-Kernen |
| WO2016062854A1 (en) * | 2014-10-24 | 2016-04-28 | Institut Pasteur | Conjugated molecules comprising a peptide derived from the cd4 receptor coupled to an anionic polypeptide for the treatment of aids |
| CA3043373A1 (en) | 2016-11-09 | 2018-05-17 | Healthtell Inc. | Pre-assembled, protected, chemically stable, chemoselective linkers |
| AU2017359450A1 (en) | 2016-11-09 | 2019-05-30 | HealthTell, Inc. | Coatings with tunable amine density |
| CN109851664A (zh) * | 2017-11-30 | 2019-06-07 | 清华大学 | 一种基于抗体反向表位设计的蛋白质及其在制备抗艾滋病病毒疫苗中的应用 |
| CN113677691A (zh) * | 2018-11-14 | 2021-11-19 | 库博科学公司 | 选择功能界面模拟物的方法及其组合物 |
| CN109836477B (zh) * | 2019-03-19 | 2022-07-12 | 山东大学 | 含有苯并噻二嗪-3-酮1,1-二氧化物的苯丙氨酸衍生物及其制备方法与应用 |
| CN110702653B (zh) * | 2019-10-16 | 2020-11-24 | 华中科技大学 | 一种聚集诱导荧光探针在指纹荧光成像中的应用 |
| CN118255684B (zh) * | 2024-03-14 | 2025-03-07 | 广州医科大学 | 一种增强CD4+T细胞分化为Th9细胞的化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2819809B1 (fr) * | 2001-01-23 | 2003-05-16 | Commissariat Energie Atomique | Peptides presentant un affinite pour la proteine virale gp120, et utilisation de ces peptides |
| FR2838649B1 (fr) * | 2002-04-19 | 2006-01-13 | Commissariat Energie Atomique | Composition anti-vih, procede de fabrication et medicament |
| CA2513213C (en) * | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US7604804B2 (en) * | 2004-02-09 | 2009-10-20 | University Of Maryland Biotechnology Institute | Enhancing anti-HIV efficiency through multivalent inhibitors targeting oligomeric gp120 |
-
2006
- 2006-06-13 WO PCT/IB2006/002332 patent/WO2007144685A1/en not_active Ceased
-
2007
- 2007-05-09 AT AT07825126T patent/ATE482978T1/de not_active IP Right Cessation
- 2007-05-09 DE DE602007009527T patent/DE602007009527D1/de active Active
- 2007-05-09 WO PCT/IB2007/002686 patent/WO2008010088A2/en not_active Ceased
- 2007-05-09 EP EP07825126A patent/EP2035453B1/de not_active Not-in-force
- 2007-05-09 US US12/304,485 patent/US8354498B2/en not_active Expired - Fee Related
- 2007-05-09 CN CNA2007800296598A patent/CN101522710A/zh active Pending
- 2007-05-09 ES ES07825126T patent/ES2371471T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8354498B2 (en) | 2013-01-15 |
| CN101522710A (zh) | 2009-09-02 |
| WO2008010088A2 (en) | 2008-01-24 |
| US20090285798A1 (en) | 2009-11-19 |
| ES2371471T3 (es) | 2012-01-03 |
| WO2007144685A1 (en) | 2007-12-21 |
| EP2035453A2 (de) | 2009-03-18 |
| DE602007009527D1 (de) | 2010-11-11 |
| WO2008010088A3 (en) | 2008-04-03 |
| EP2035453B1 (de) | 2010-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |