ATE483718T1 - Verfahren zur synthese von terbinafin und derivaten davon - Google Patents
Verfahren zur synthese von terbinafin und derivaten davonInfo
- Publication number
- ATE483718T1 ATE483718T1 AT05719027T AT05719027T ATE483718T1 AT E483718 T1 ATE483718 T1 AT E483718T1 AT 05719027 T AT05719027 T AT 05719027T AT 05719027 T AT05719027 T AT 05719027T AT E483718 T1 ATE483718 T1 AT E483718T1
- Authority
- AT
- Austria
- Prior art keywords
- terbinafin
- synthesis
- derivatives
- terbinafine
- analogues
- Prior art date
Links
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010189 synthetic method Methods 0.000 abstract 1
- 229960002722 terbinafine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Catalysts (AREA)
- Nonwoven Fabrics (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001154A ITMI20041154A1 (it) | 2004-06-09 | 2004-06-09 | Procedimento di sintesi di terbinafina e suoi derivati |
| PCT/IT2005/000121 WO2005121155A1 (en) | 2004-06-09 | 2005-03-04 | A process for the synthesis of terbinafine and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE483718T1 true ATE483718T1 (de) | 2010-10-15 |
Family
ID=34963051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05719027T ATE483718T1 (de) | 2004-06-09 | 2005-03-04 | Verfahren zur synthese von terbinafin und derivaten davon |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7838704B2 (de) |
| EP (1) | EP1753770B1 (de) |
| JP (1) | JP4733129B2 (de) |
| KR (1) | KR101159814B1 (de) |
| CN (1) | CN1993369B (de) |
| AT (1) | ATE483718T1 (de) |
| CA (1) | CA2569328C (de) |
| DE (1) | DE602005023985D1 (de) |
| IL (1) | IL179832A (de) |
| IT (1) | ITMI20041154A1 (de) |
| WO (1) | WO2005121155A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20061573A1 (it) * | 2006-08-04 | 2008-02-05 | F I S Fabbrica Italiana Sintetici Spa | Processo per la preparazione di 1,1-dicloro-2-alchiletilene |
| CA2706465A1 (en) * | 2007-11-21 | 2009-05-28 | Pharmaxis Ltd. | Haloallylamine inhibitors of ssao/vap-1 and uses therefor |
| JP2012136472A (ja) * | 2010-12-27 | 2012-07-19 | Shin-Etsu Chemical Co Ltd | 精製アミノシランの製造方法 |
| CN102898314B (zh) * | 2012-11-13 | 2014-09-03 | 山东铂源药业有限公司 | 一种盐酸特比萘芬的制备方法 |
| CN105016966A (zh) * | 2015-07-31 | 2015-11-04 | 江苏恒润制药有限公司 | 一种（e）-1-氯-6,6-二甲基-2-庚烯-4-炔的制备方法 |
| CN108017544B (zh) * | 2017-12-28 | 2020-05-08 | 山东铂源药业有限公司 | 一种特比萘芬的合成方法 |
| CN110423200B (zh) * | 2019-08-29 | 2022-03-25 | 成都奥邦药业有限公司 | 一种提高盐酸特比萘芬纯度的方法 |
| CN111606811B (zh) * | 2020-06-04 | 2022-09-06 | 山东安弘制药有限公司 | 一种盐酸特比萘芬的制备方法 |
| CN114195631B (zh) * | 2021-12-20 | 2024-03-29 | 大连奇凯医药科技有限公司 | 一种3,3-二甲基丁酸的制备工艺 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT376404B (de) * | 1983-04-08 | 1984-11-26 | Stiepock Herbert | Transportanhaenger fuer mindestens ein segelbrett |
| NZ280065A (en) * | 1995-09-20 | 1998-04-27 | Apotex Inc | Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives |
| ITMI20010430A1 (it) | 2001-03-02 | 2002-09-02 | Dinamite Dipharma S P A In For | Metodo per la sintesi di terbinafina |
| ITMI20022534A1 (it) * | 2002-11-29 | 2004-05-30 | Dinamite Dipharma S P A | Procedimento per la preparazione di terbinafina mediante l'uso di platino come catalizzatore. |
-
2004
- 2004-06-09 IT IT001154A patent/ITMI20041154A1/it unknown
-
2005
- 2005-03-04 KR KR1020067025962A patent/KR101159814B1/ko not_active Expired - Fee Related
- 2005-03-04 CN CN2005800187712A patent/CN1993369B/zh not_active Expired - Fee Related
- 2005-03-04 CA CA2569328A patent/CA2569328C/en not_active Expired - Fee Related
- 2005-03-04 EP EP05719027A patent/EP1753770B1/de not_active Expired - Lifetime
- 2005-03-04 WO PCT/IT2005/000121 patent/WO2005121155A1/en not_active Ceased
- 2005-03-04 JP JP2007526710A patent/JP4733129B2/ja not_active Expired - Fee Related
- 2005-03-04 AT AT05719027T patent/ATE483718T1/de not_active IP Right Cessation
- 2005-03-04 DE DE602005023985T patent/DE602005023985D1/de not_active Expired - Lifetime
- 2005-03-04 US US11/628,252 patent/US7838704B2/en not_active Expired - Fee Related
-
2006
- 2006-12-04 IL IL179832A patent/IL179832A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1753770A1 (de) | 2007-02-21 |
| US20070244336A1 (en) | 2007-10-18 |
| IL179832A (en) | 2011-06-30 |
| DE602005023985D1 (de) | 2010-11-18 |
| CN1993369A (zh) | 2007-07-04 |
| JP4733129B2 (ja) | 2011-07-27 |
| CN1993369B (zh) | 2010-09-29 |
| IL179832A0 (en) | 2007-05-15 |
| EP1753770B1 (de) | 2010-10-06 |
| KR20070030212A (ko) | 2007-03-15 |
| WO2005121155A1 (en) | 2005-12-22 |
| CA2569328A1 (en) | 2005-12-22 |
| KR101159814B1 (ko) | 2012-06-26 |
| CA2569328C (en) | 2013-09-10 |
| JP2008501784A (ja) | 2008-01-24 |
| WO2005121155A8 (en) | 2006-03-16 |
| US7838704B2 (en) | 2010-11-23 |
| ITMI20041154A1 (it) | 2004-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |