ATE483968T1 - Drehbarer konfokaler scanner zur detektion von kapillaranordnungen - Google Patents

Drehbarer konfokaler scanner zur detektion von kapillaranordnungen

Info

Publication number
ATE483968T1
ATE483968T1 AT99903338T AT99903338T ATE483968T1 AT E483968 T1 ATE483968 T1 AT E483968T1 AT 99903338 T AT99903338 T AT 99903338T AT 99903338 T AT99903338 T AT 99903338T AT E483968 T1 ATE483968 T1 AT E483968T1
Authority
AT
Austria
Prior art keywords
rotatable
confocal scanner
detecting capillary
capillary arrangements
detecting
Prior art date
Application number
AT99903338T
Other languages
English (en)
Inventor
Richard Mathies
James Scherer
David Wexler
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE483968T1 publication Critical patent/ATE483968T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Electrochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Mechanical Optical Scanning Systems (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT99903338T 1998-01-29 1999-01-25 Drehbarer konfokaler scanner zur detektion von kapillaranordnungen ATE483968T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/015,198 US6100535A (en) 1998-01-29 1998-01-29 Rotary confocal scanner for detection of capillary arrays
PCT/US1999/001446 WO1999039193A1 (en) 1998-01-29 1999-01-25 Rotary confocal scanner for detection of capillary arrays

Publications (1)

Publication Number Publication Date
ATE483968T1 true ATE483968T1 (de) 2010-10-15

Family

ID=21770050

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99903338T ATE483968T1 (de) 1998-01-29 1999-01-25 Drehbarer konfokaler scanner zur detektion von kapillaranordnungen

Country Status (8)

Country Link
US (1) US6100535A (de)
EP (1) EP1051612B1 (de)
JP (2) JP3566207B2 (de)
AT (1) ATE483968T1 (de)
AU (1) AU2338699A (de)
CA (1) CA2317521C (de)
DE (1) DE69942825D1 (de)
WO (1) WO1999039193A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627446B1 (en) * 1998-07-02 2003-09-30 Amersham Biosciences (Sv) Corp Robotic microchannel bioanalytical instrument
JP3613032B2 (ja) * 1998-10-26 2005-01-26 株式会社日立製作所 キャピラリーアレイ電気泳動装置
US6296749B1 (en) * 1999-04-13 2001-10-02 The Regents Of The University Of California System and method for chromatography and electrophoresis using circular optical scanning
EP1983331B1 (de) * 1999-05-28 2011-07-13 Yokogawa Electric Corporation Optische Anordnung zur Auswertung eines Biochips
AU773950B2 (en) * 1999-07-16 2004-06-10 Applera Corporation High density electrophoresis device and method
AU7747600A (en) 1999-10-01 2002-05-15 University Of California, The Microfabricated liquid sample loading system
US6531041B1 (en) * 2000-07-20 2003-03-11 Symyx Technologies, Inc. Multiplexed capillary electrophoresis system with rotatable photodetector
JP2002365251A (ja) * 2001-06-07 2002-12-18 Nippon Sheet Glass Co Ltd マイクロ化学システム
JP3678192B2 (ja) * 2001-11-21 2005-08-03 横河電機株式会社 計測装置
WO2003095989A1 (en) 2002-05-10 2003-11-20 Applera Corporation Imaging system for reduction of interstitial image regions and its related method
AU2003275940A1 (en) * 2002-10-31 2004-05-25 Chemometec A/S A method for assessment of particles
US7159479B1 (en) * 2003-09-25 2007-01-09 Lockheed Martin Corporation Active damper for stabilized mirrors
US7211184B2 (en) * 2004-08-04 2007-05-01 Ast Management Inc. Capillary electrophoresis devices
US8276760B2 (en) * 2006-11-30 2012-10-02 Palo Alto Research Center Incorporated Serpentine structures for continuous flow particle separations
US9486812B2 (en) * 2006-11-30 2016-11-08 Palo Alto Research Center Incorporated Fluidic structures for membraneless particle separation
US10052571B2 (en) * 2007-11-07 2018-08-21 Palo Alto Research Center Incorporated Fluidic device and method for separation of neutrally buoyant particles
US8931644B2 (en) * 2006-11-30 2015-01-13 Palo Alto Research Center Incorporated Method and apparatus for splitting fluid flow in a membraneless particle separation system
US9433880B2 (en) * 2006-11-30 2016-09-06 Palo Alto Research Center Incorporated Particle separation and concentration system
US9862624B2 (en) 2007-11-07 2018-01-09 Palo Alto Research Center Incorporated Device and method for dynamic processing in water purification
FI120089B (fi) * 2008-01-23 2009-06-30 Kone Corp Menetelmä hissin asentamiseksi
WO2009136232A1 (en) * 2008-05-05 2009-11-12 Korkut Celal Vata Automated, high band resolution electrophoretic system for digital visualization and method of use
US8357281B2 (en) * 2009-09-21 2013-01-22 Advanced Analytical Technologies, Inc. Multi-wavelength fluorescence detection system for multiplexed capillary electrophoresis
CN111157508B (zh) 2020-03-06 2022-09-06 成都博奥晶芯生物科技有限公司 一种微流体芯片荧光数据连续采集方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091652A (en) * 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
US5274240A (en) * 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
JP3563140B2 (ja) * 1995-01-19 2004-09-08 株式会社日立製作所 キャピラリーアレイ電気泳動装置
JPH07103941A (ja) * 1993-09-30 1995-04-21 Shimadzu Corp 電気泳動装置
US5538613A (en) * 1993-10-26 1996-07-23 Genesys Technologies, Inc. Electrophoresis analyzer
US5483075A (en) * 1994-11-01 1996-01-09 Perkin-Elmer Corporation Rotary scanning apparatus
US5675155A (en) * 1995-04-26 1997-10-07 Beckman Instruments, Inc. Multicapillary fluorescent detection system
AU702403B2 (en) * 1995-12-05 1999-02-18 Gamera Bioscience Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
JP3180072B2 (ja) * 1997-09-11 2001-06-25 日立ソフトウエアエンジニアリング株式会社 発光パターン読み取り装置

Also Published As

Publication number Publication date
JP3566207B2 (ja) 2004-09-15
WO1999039193A1 (en) 1999-08-05
JP2004220046A (ja) 2004-08-05
JP4489479B2 (ja) 2010-06-23
CA2317521C (en) 2003-12-23
EP1051612A1 (de) 2000-11-15
AU2338699A (en) 1999-08-16
DE69942825D1 (de) 2010-11-18
JP2002502029A (ja) 2002-01-22
CA2317521A1 (en) 1999-08-05
EP1051612B1 (de) 2010-10-06
US6100535A (en) 2000-08-08

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