ATE486067T1 - Dibenzosuberon-derivate - Google Patents

Dibenzosuberon-derivate

Info

Publication number: ATE486067T1
Authority: AT; Austria
Prior art keywords: sup; dibenzosuberone; derivatives; sub; compounds
Prior art date: 2004-11-09

Application number

AT05807334T

Other languages

English (en)

Inventor

Jean-Marc Plancher

Sven Taylor

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-09

Filing date

2005-11-02

Publication date

2010-11-15

2005-11-02 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2010-11-15 Application granted granted Critical

2010-11-15 Publication of ATE486067T1 publication Critical patent/ATE486067T1/de

Links

BMVWCPGVLSILMU-UHFFFAOYSA-N 5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-one Chemical class C1CC2=CC=CC=C2C(=O)C2=CC=CC=C21 BMVWCPGVLSILMU-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Psychology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Otolaryngology (AREA)
Immunology (AREA)

AT05807334T 2004-11-09 2005-11-02 Dibenzosuberon-derivate ATE486067T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP04105627		2004-11-09
PCT/EP2005/011681 WO2006050842A1 (en)	2004-11-09	2005-11-02	Dibenzosuberone derivatives

Publications (1)

Publication Number	Publication Date
ATE486067T1 true ATE486067T1 (de)	2010-11-15

Family

ID=35559277

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05807334T ATE486067T1 (de)	2004-11-09	2005-11-02	Dibenzosuberon-derivate

Country Status (14)

Country	Link
US (1)	US7220743B2 (de)
EP (1)	EP1812418B1 (de)
JP (1)	JP4675969B2 (de)
KR (1)	KR100896353B1 (de)
CN (1)	CN101052632A (de)
AT (1)	ATE486067T1 (de)
AU (1)	AU2005304039A1 (de)
BR (1)	BRPI0517653A (de)
CA (1)	CA2586068A1 (de)
DE (1)	DE602005024430D1 (de)
ES (1)	ES2351348T3 (de)
MX (1)	MX2007005323A (de)
RU (1)	RU2391337C2 (de)
WO (1)	WO2006050842A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN115677453B (zh) *	2023-01-03	2023-04-07	凯莱英生命科学技术(天津)有限公司	2,2-二氯丙烷的制备方法和纯化方法

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FR2714057B1 (fr)	1993-12-17	1996-03-08	Sanofi Elf	Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
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FR2789079B3 (fr)	1999-02-01	2001-03-02	Sanofi Synthelabo	Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant
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US6566356B2 (en) *	2000-03-03	2003-05-20	Aventis Pharma S.A.	Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
FR2805818B1 (fr)	2000-03-03	2002-04-26	Aventis Pharma Sa	Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
FR2805810B1 (fr)	2000-03-03	2002-04-26	Aventis Pharma Sa	Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
US6355631B1 (en) *	2000-03-03	2002-03-12	Aventis Pharma S.A.	Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation
FR2805817B1 (fr)	2000-03-03	2002-04-26	Aventis Pharma Sa	Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
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PL208098B1 (pl)	2000-03-23	2011-03-31	Solvay Pharm Bv	Pochodne 4,5-dihydro-1H-pirazolu, kompozycja farmaceutyczna, sposób wytwarzania związków oraz ich zastosowanie
FR2814678B1 (fr)	2000-10-04	2002-12-20	Aventis Pharma Sa	Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite
US20020130953A1 (en) *	2001-03-13	2002-09-19	John Riconda	Enhanced display of environmental navigation features to vehicle operator
CZ2003698A3 (cs)	2001-03-22	2003-06-18	Solvay Pharmaceuticals B. V.	4,5-Dihydro-1H-pyrazolové deriváty mající CB1-antagonistickou účinnost
JP2005507875A (ja)	2001-08-31	2005-03-24	ユニバーシティオブコネチカット	カンナビノイド受容体に作用する新規なピラゾール類似体
PE20030547A1 (es)	2001-09-24	2003-08-18	Bayer Corp	Derivados de imidazol para el tratamiento de la obesidad
CA2463441A1 (en)	2001-10-12	2003-05-08	Bayer Pharmaceuticals Corporation	Phenyl substituted 5-membered nitrogen containing heterocycles for the treatment of obesity
WO2003035005A2 (en)	2001-10-26	2003-05-01	University Of Connecticut	Heteroindanes: a new class of potent cannabimimetic ligands
SE0104332D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
AU2003209388A1 (en)	2002-01-29	2003-09-02	Merck And Co., Inc.	Substituted imidazoles as cannabinoid receptor modulators
ATE486842T1 (de)	2002-03-12	2010-11-15	Merck Sharp & Dohme	Substituierte amide
AR038966A1 (es)	2002-03-18	2005-02-02	Solvay Pharm Bv	Derivados de tiazol que tienen actividad antagonista, agonista o agonista parcial de cb1
AU2003215024B2 (en)	2002-03-26	2008-02-21	Merck Sharp & Dohme Corp.	Spirocyclic amides as cannabinoid receptor modulators
ES2192494B1 (es)	2002-03-27	2005-02-16	Consejo Superior De Investigaciones Cientificas	Derivados de 1,2,4-triazol con propiedades cannabinoides.
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FR2838438A1 (fr)	2002-04-11	2003-10-17	Sanofi Synthelabo	Derives de diphenylpyridine,leur preparation, les compositions pharmaceutiques en contenant
FR2838439B1 (fr)	2002-04-11	2005-05-20	Sanofi Synthelabo	Derives de terphenyle, leur preparation, les compositions pharmaceutqiues en contenant
EP1499306A4 (de)	2002-04-12	2007-03-28	Merck & Co Inc	Bicyclische amide
AU2003250117B2 (en) *	2002-07-29	2007-05-10	F. Hoffmann-La Roche Ag	Novel benzodioxoles
WO2005075450A2 (en) *	2004-01-28	2005-08-18	F. Hoffmann-La Roche Ag	Spiro-benzodioxoles and their use as cb1 antagonists

2005
- 2005-11-02 KR KR1020077010444A patent/KR100896353B1/ko not_active Expired - Fee Related
- 2005-11-02 MX MX2007005323A patent/MX2007005323A/es active IP Right Grant
- 2005-11-02 AT AT05807334T patent/ATE486067T1/de active
- 2005-11-02 ES ES05807334T patent/ES2351348T3/es not_active Expired - Lifetime
- 2005-11-02 CA CA002586068A patent/CA2586068A1/en not_active Abandoned
- 2005-11-02 CN CNA2005800378743A patent/CN101052632A/zh active Pending
- 2005-11-02 JP JP2007540539A patent/JP4675969B2/ja not_active Expired - Fee Related
- 2005-11-02 AU AU2005304039A patent/AU2005304039A1/en not_active Abandoned
- 2005-11-02 WO PCT/EP2005/011681 patent/WO2006050842A1/en not_active Ceased
- 2005-11-02 BR BRPI0517653-0A patent/BRPI0517653A/pt not_active IP Right Cessation
- 2005-11-02 RU RU2007121506/04A patent/RU2391337C2/ru not_active IP Right Cessation
- 2005-11-02 DE DE602005024430T patent/DE602005024430D1/de not_active Expired - Lifetime
- 2005-11-02 EP EP05807334A patent/EP1812418B1/de not_active Expired - Lifetime
- 2005-11-03 US US11/266,445 patent/US7220743B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2391337C2 (ru)	2010-06-10
JP2008519082A (ja)	2008-06-05
AU2005304039A1 (en)	2006-05-18
US20060100206A1 (en)	2006-05-11
BRPI0517653A (pt)	2008-10-14
JP4675969B2 (ja)	2011-04-27
MX2007005323A (es)	2007-06-12
RU2007121506A (ru)	2008-12-20
ES2351348T3 (es)	2011-02-03
US7220743B2 (en)	2007-05-22
KR20070062603A (ko)	2007-06-15
CA2586068A1 (en)	2006-05-18
KR100896353B1 (ko)	2009-05-08
WO2006050842A1 (en)	2006-05-18
EP1812418A1 (de)	2007-08-01
CN101052632A (zh)	2007-10-10
EP1812418B1 (de)	2010-10-27
DE602005024430D1 (de)	2010-12-09

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2011-07-15

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SE0303180D0 (sv)	2003-11-26	Novel compounds
SE0302232D0 (sv)	2003-08-18	Novel Compounds
JO2764B1 (en)	2014-03-15	Indole derivatives or benzimidazole derivatives to modify the enzyme AKP kinase
NO20082136L (no)	2008-06-30	1,5-substituerte indol-2-yl-amidderivater
MY135841A (en)	2008-07-31	Novel benzodioxoles
SE0201635D0 (sv)	2002-05-30	Novel compounds
UY29246A1 (es)	2006-08-31	Nuevos compuestos
NO20082096L (no)	2008-05-29	Azaindol-2-karboksamidderivativer
ATE384058T1 (de)	2008-02-15	Thiazolderivate
UA83875C2 (ru)	2008-08-26	Производные хинолина для применения в качестве микобактериальных ингибиторов
MXPA05007115A (es)	2005-11-16	Nuevos agonistas inversos del receptor cb 1.
IL191751A0 (en)	2008-12-29	Pyrrolo[2,3-c]pyridine derivatives
MX2007011695A (es)	2008-03-11	Derivados de oxindol sustituido, medicamentos que contienen dichos derivados y uso de los mismos.
MXPA05011198A (es)	2005-12-14	Derivados de oxifenilo aromaticos y de sulfanilfenilo aromaticos.
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