ATE486865T1 - Hydroxycarbonylphenyl substituierte 4- (aminomethyl)-piperidinbenzamide als 5ht4- antagonisten - Google Patents
Hydroxycarbonylphenyl substituierte 4- (aminomethyl)-piperidinbenzamide als 5ht4- antagonistenInfo
- Publication number
- ATE486865T1 ATE486865T1 AT04739777T AT04739777T ATE486865T1 AT E486865 T1 ATE486865 T1 AT E486865T1 AT 04739777 T AT04739777 T AT 04739777T AT 04739777 T AT04739777 T AT 04739777T AT E486865 T1 ATE486865 T1 AT E486865T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidinebenzamide
- hydroxycarbonylphenyl
- aminomethyl
- antagonists
- substituted
- Prior art date
Links
- BQNIFTLCQBTDOH-UHFFFAOYSA-N 2-[4-(aminomethyl)piperidin-1-yl]benzamide Chemical class C1CC(CN)CCN1C1=CC=CC=C1C(N)=O BQNIFTLCQBTDOH-UHFFFAOYSA-N 0.000 title 1
- -1 HYDROXYCARBONYLPHENYL Chemical group 0.000 title 1
- 239000003523 serotonin 4 antagonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP0350239 | 2003-06-19 | ||
| PCT/EP2004/006274 WO2005003121A1 (en) | 2003-06-19 | 2004-06-10 | Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE486865T1 true ATE486865T1 (de) | 2010-11-15 |
Family
ID=33560736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04739777T ATE486865T1 (de) | 2003-06-19 | 2004-06-10 | Hydroxycarbonylphenyl substituierte 4- (aminomethyl)-piperidinbenzamide als 5ht4- antagonisten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7498347B2 (de) |
| EP (1) | EP1641782B1 (de) |
| JP (1) | JP4688798B2 (de) |
| KR (1) | KR101151641B1 (de) |
| AT (1) | ATE486865T1 (de) |
| AU (1) | AU2004254191B2 (de) |
| CA (1) | CA2528653C (de) |
| DE (1) | DE602004029888D1 (de) |
| EA (1) | EA009464B1 (de) |
| ES (1) | ES2355824T3 (de) |
| WO (1) | WO2005003121A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0901487D0 (en) | 2009-01-30 | 2009-03-11 | Movetis N V | Asthma Therapy |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2103675B1 (es) * | 1995-01-10 | 1998-07-01 | Almirall Lab | Nuevas piperidinas sustituidas. |
| CA2340952C (en) * | 1998-09-10 | 2009-12-08 | F. Hoffmann-La Roche Ag | Dihydrobenzodioxine carboxamide and ketone derivatives as 5-ht4 receptor antagonists |
| TW570920B (en) * | 1998-12-22 | 2004-01-11 | Janssen Pharmaceutica Nv | 4-(aminomethyl)-piperidine benzamides for treating gastrointestinal disorders |
-
2004
- 2004-06-10 US US10/560,555 patent/US7498347B2/en not_active Expired - Fee Related
- 2004-06-10 DE DE602004029888T patent/DE602004029888D1/de not_active Expired - Lifetime
- 2004-06-10 CA CA2528653A patent/CA2528653C/en not_active Expired - Fee Related
- 2004-06-10 EP EP04739777A patent/EP1641782B1/de not_active Expired - Lifetime
- 2004-06-10 EA EA200600057A patent/EA009464B1/ru not_active IP Right Cessation
- 2004-06-10 AT AT04739777T patent/ATE486865T1/de not_active IP Right Cessation
- 2004-06-10 AU AU2004254191A patent/AU2004254191B2/en not_active Ceased
- 2004-06-10 WO PCT/EP2004/006274 patent/WO2005003121A1/en not_active Ceased
- 2004-06-10 ES ES04739777T patent/ES2355824T3/es not_active Expired - Lifetime
- 2004-06-10 JP JP2006515880A patent/JP4688798B2/ja not_active Expired - Fee Related
-
2005
- 2005-12-19 KR KR1020057024323A patent/KR101151641B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4688798B2 (ja) | 2011-05-25 |
| JP2007526874A (ja) | 2007-09-20 |
| AU2004254191B2 (en) | 2010-03-11 |
| WO2005003121A1 (en) | 2005-01-13 |
| US20060142340A1 (en) | 2006-06-29 |
| EP1641782B1 (de) | 2010-11-03 |
| US7498347B2 (en) | 2009-03-03 |
| KR20060022704A (ko) | 2006-03-10 |
| ES2355824T3 (es) | 2011-03-31 |
| CA2528653C (en) | 2012-01-10 |
| EP1641782A1 (de) | 2006-04-05 |
| KR101151641B1 (ko) | 2012-06-08 |
| DE602004029888D1 (en) | 2010-12-16 |
| EA009464B1 (ru) | 2007-12-28 |
| CA2528653A1 (en) | 2005-01-13 |
| EA200600057A1 (ru) | 2006-06-30 |
| AU2004254191A1 (en) | 2005-01-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1106857T1 (el) | Βενζαμιδια 4-(αμινομεθυλ)-πιπεριδινης ως 5ht4-ανταγωνιστες | |
| CY1117330T1 (el) | Βενζοδιοξινυλ υποκατεστημενα παραγωγα ινδαζολιου | |
| SE0302232D0 (sv) | Novel Compounds | |
| EA200900658A1 (ru) | Производные индазолилэфиров или -амидов для лечения расстройств, опосредованных глюкокортиодными рецепторами | |
| TW200602338A (en) | Selected CGRP antagonists, process for preparing them and their use as pharmaceutical compositions | |
| DE602005014086D1 (de) | Pyrimidinderivate als orexin-rezeptorantagonisten | |
| SE0302760D0 (sv) | New compounds | |
| MY136959A (en) | Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof | |
| DK1814846T3 (da) | 11beta-HSD1-inhibitorer | |
| CY1108880T1 (el) | Παραγωγα καρβοξαμιδιου ως ανταγωνιστες μουσκαρινικου υποδοχεα | |
| ATE552246T1 (de) | Substituierte aryloxy-n- bicyclomethylacetamidverbindungen als vr1- antagonisten | |
| EA200601295A1 (ru) | Производные 1,3-диоксана и их аналоги, применимые для лечения i.a. ожирения и диабета | |
| EA200600060A1 (ru) | Аминосульфонилзамещенные 4-(аминометил) пиперидинбензамиды в качестве 5нт-антагонистов | |
| DE602004029355D1 (de) | Sulfopyrrolderivate | |
| JO2937B1 (en) | Tight muscles of the peptide vascular tensioner receptor | |
| TW200800962A (en) | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | |
| CY1107097T1 (el) | 5ht4-ανταγωνιστικα βενζαμιδια 4-( αμινομεθυλ) - πιπεριδινης | |
| NO20050270L (no) | Nye forbindelser, deres anvendelse og fremstilling | |
| NO20060718L (no) | Substituerte tiofoner og deres anvendelse | |
| ATE550326T1 (de) | Als modulatoren von hdl einsetzbare verbindungen | |
| ATE486865T1 (de) | Hydroxycarbonylphenyl substituierte 4- (aminomethyl)-piperidinbenzamide als 5ht4- antagonisten | |
| DE602004024200D1 (de) | Heterocyclisch substituierte 4-(aminomethyl)-piperidinbenzamide als 5ht4-antagonisten | |
| EA200801549A1 (ru) | Новые производные фенантридина в качестве антагонистов брадикинина | |
| DE602004009306D1 (de) | 3,4-dihydro-1h-chinolin-2-onderivate als norepinephrin-wiederaufnahme-hemmern | |
| ATE522530T1 (de) | 2-piperazin-1-yl-3h-imidazoä4,5-bü- pyridinderivate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |