ATE486958T1 - Verfahren zur bestimmung von nukleinsäuresequenzen in urin - Google Patents
Verfahren zur bestimmung von nukleinsäuresequenzen in urinInfo
- Publication number
- ATE486958T1 ATE486958T1 AT05077010T AT05077010T ATE486958T1 AT E486958 T1 ATE486958 T1 AT E486958T1 AT 05077010 T AT05077010 T AT 05077010T AT 05077010 T AT05077010 T AT 05077010T AT E486958 T1 ATE486958 T1 AT E486958T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- acid sequence
- urine sample
- urine
- acid sequences
- Prior art date
Links
- 150000007523 nucleic acids Chemical group 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 5
- 210000002700 urine Anatomy 0.000 title abstract 5
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 4
- 230000004888 barrier function Effects 0.000 abstract 2
- 210000003734 kidney Anatomy 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 210000001635 urinary tract Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4817097P | 1997-05-30 | 1997-05-30 | |
| US4838197P | 1997-06-30 | 1997-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE486958T1 true ATE486958T1 (de) | 2010-11-15 |
Family
ID=26725864
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10161334T ATE557103T1 (de) | 1997-05-30 | 1998-05-29 | Verfahren zur erkennung von nukleinsäuresequenzen in urin |
| AT05077010T ATE486958T1 (de) | 1997-05-30 | 1998-05-29 | Verfahren zur bestimmung von nukleinsäuresequenzen in urin |
| AT98924998T ATE320505T1 (de) | 1997-05-30 | 1998-05-29 | Verfahren zur bestimmung von nukleinsäuresequenzen in urin |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10161334T ATE557103T1 (de) | 1997-05-30 | 1998-05-29 | Verfahren zur erkennung von nukleinsäuresequenzen in urin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98924998T ATE320505T1 (de) | 1997-05-30 | 1998-05-29 | Verfahren zur bestimmung von nukleinsäuresequenzen in urin |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6251638B1 (de) |
| EP (3) | EP0920539B9 (de) |
| AT (3) | ATE557103T1 (de) |
| AU (1) | AU7703998A (de) |
| CY (1) | CY1113124T1 (de) |
| DE (2) | DE69833856T2 (de) |
| DK (3) | DK1634966T3 (de) |
| ES (3) | ES2389055T3 (de) |
| PT (1) | PT2216416E (de) |
| WO (1) | WO1998054364A1 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451523B1 (en) * | 1994-09-14 | 2002-09-17 | Interneuron Pharmaceuticals, Inc. | Detection of a leptin receptor variant and methods for regulating obesity |
| DE69840669D1 (de) | 1997-04-10 | 2009-04-30 | Stichting Katholieke Univ | Pca3, pca3-gene und verfahren zu ihrer verwendung |
| USRE39920E1 (en) * | 1997-05-30 | 2007-11-13 | Xenomics, Inc. | Methods for detection of nucleic acid sequences in urine |
| US7060458B1 (en) * | 1997-08-14 | 2006-06-13 | Wyeth | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| US20030022293A1 (en) * | 1997-09-18 | 2003-01-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| US20030068731A1 (en) * | 1997-12-17 | 2003-04-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030113842A1 (en) * | 1998-03-11 | 2003-06-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030166132A1 (en) * | 1998-08-26 | 2003-09-04 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6936697B2 (en) * | 1998-09-01 | 2005-08-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| AU6316100A (en) * | 1999-07-30 | 2001-02-19 | Mitsubishi Pharma Corporation | Gene of human brain type pgt |
| JP4018304B2 (ja) * | 1999-08-27 | 2007-12-05 | 独立行政法人科学技術振興機構 | 高親和性コリントランスポーター |
| EP1222266B1 (de) * | 1999-09-29 | 2006-03-29 | Diagnocure Inc. | Pca3 mrna in gutartigen und bösartigen prostatageweben |
| EP1201681A1 (de) * | 2000-10-30 | 2002-05-02 | Millennium Pharmaceuticals, Inc. | "Fail" Moleküle und deren Verwendung |
| CA2428757A1 (en) * | 2000-11-15 | 2002-07-18 | Roche Diagnostics Corporation | Methods and reagents for identifying rare fetal cells in the maternal circulation |
| US7029840B2 (en) * | 2000-11-15 | 2006-04-18 | Becton, Dickinson And Company | Method for preservation of cells and nucleic acid targets |
| AU2002243633A1 (en) * | 2001-01-23 | 2002-08-06 | Lexicon Genetics Incorporated | Human ion exchanger proteins and polynucleotides encoding the same |
| US20030144196A1 (en) * | 2001-08-21 | 2003-07-31 | Bowen Michael A. | Activated T lymphocyte nucleic acid sequences and polypeptides encoded by same |
| US20030211522A1 (en) * | 2002-01-18 | 2003-11-13 | Landes Gregory M. | Methods for fetal DNA detection and allele quantitation |
| US7776524B2 (en) * | 2002-02-15 | 2010-08-17 | Genzyme Corporation | Methods for analysis of molecular events |
| US7217515B2 (en) * | 2002-09-30 | 2007-05-15 | Chi Mei Foundation Medical Center | HURP gene as a molecular marker for bladder cancer |
| CA2445204C (en) | 2002-10-16 | 2014-08-12 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
| EP1592809B1 (de) | 2003-02-07 | 2013-04-10 | Diagnocure Inc. | Verfahren zum nachweis von prostatakrebs in einer probe |
| EP1584923A3 (de) * | 2004-04-07 | 2006-01-04 | Roche Diagnostics GmbH | Stabilisierung von Biomolekülen in Proben |
| WO2005111244A2 (en) * | 2004-05-10 | 2005-11-24 | Exact Sciences Corporation | Methods for detecting a mutant nucleic acid |
| WO2006012522A1 (en) | 2004-07-23 | 2006-02-02 | Pacific Edge Biotechnology Ltd. | Urine markers for detection of bladder cancer |
| WO2006026654A2 (en) | 2004-08-27 | 2006-03-09 | Exact Sciences Corporation | Method for detecting a recombinant event |
| CA2584723A1 (en) | 2004-10-22 | 2006-05-04 | Redpath Integrated Pathology, Inc. | Enhanced amplifiability of minute fixative-treated tissue samples, minute stained cytology samples, and other minute sources of dna |
| US9109256B2 (en) | 2004-10-27 | 2015-08-18 | Esoterix Genetic Laboratories, Llc | Method for monitoring disease progression or recurrence |
| CA2491067A1 (en) | 2004-12-24 | 2006-06-24 | Stichting Katholieke Universiteit | Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer |
| ITRM20050067A1 (it) | 2005-02-17 | 2006-08-18 | Istituto Naz Per Le Malattie I | Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine. |
| US7914982B2 (en) | 2005-02-17 | 2011-03-29 | Trovagene, Inc. | Methods for detecting pathogen specific nucleic acids in urine |
| EP2351857B1 (de) | 2005-02-17 | 2014-10-29 | TrovaGene, Inc. | Zusammensetzungen und Verfahren zum Nachweis von für Krankheitserreger spezifischen Nukleinsäuren in Urin |
| ITRM20050068A1 (it) * | 2005-02-17 | 2006-08-18 | Istituto Naz Per Le Malattie I | Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine. |
| US7449297B2 (en) * | 2005-04-14 | 2008-11-11 | Euclid Diagnostics Llc | Methods of copying the methylation pattern of DNA during isothermal amplification and microarrays |
| US9777314B2 (en) * | 2005-04-21 | 2017-10-03 | Esoterix Genetic Laboratories, Llc | Analysis of heterogeneous nucleic acid samples |
| NZ545243A (en) * | 2006-02-10 | 2009-07-31 | Pacific Edge Biotechnology Ltd | Urine gene expression ratios for detection of cancer |
| WO2008070862A2 (en) * | 2006-12-07 | 2008-06-12 | Biocept, Inc. | Non-invasive prenatal genetic screen |
| WO2008075790A2 (en) * | 2006-12-20 | 2008-06-26 | Olympus Corporation | Method for detecting cancer with nucleic acids in blood |
| HUE019019T5 (en) * | 2007-08-22 | 2017-04-28 | Trovagene Inc | Methods for Using miRNA for In vivo Cell Death Detection |
| WO2009049147A2 (en) * | 2007-10-10 | 2009-04-16 | Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine | Method of tumor screening by detection of tumour marker in low molecular weight nucleic acid from urine |
| JP2011511644A (ja) * | 2008-02-12 | 2011-04-14 | ノバルティス アーゲー | 無細胞のアポトーシス性核酸または胎児核酸を単離するための方法 |
| EP2271772B1 (de) * | 2008-03-11 | 2014-07-16 | Sequenom, Inc. | Tests auf nukleinsäurebasis zur pränatalen geschlechtsbestimmung |
| EP2853601B1 (de) | 2008-07-18 | 2016-09-21 | TrovaGene, Inc. | Verfahren für den PCR-basierten Nachweis ultrakurzer Nukleinsäuresequenzen |
| US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| NO2398912T3 (de) | 2009-02-18 | 2018-02-10 | ||
| US20110111410A1 (en) * | 2009-11-09 | 2011-05-12 | Streck, Inc. | Stabilization of rna in intact cells within a blood sample |
| ES2577017T3 (es) | 2009-12-22 | 2016-07-12 | Sequenom, Inc. | Procedimientos y kits para identificar la aneuploidia |
| AU2012249531B2 (en) | 2011-04-29 | 2017-06-29 | Sequenom, Inc. | Quantification of a minority nucleic acid species |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| PL2561103T3 (pl) | 2011-06-29 | 2015-02-27 | Bgi Diagnosis Co Ltd | Nieinwazyjna detekcja anomalii genetycznych płodu |
| EP2820129A1 (de) | 2012-03-02 | 2015-01-07 | Sequenom, Inc. | Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen |
| US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
| US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US20140093873A1 (en) | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US9341628B2 (en) | 2012-11-30 | 2016-05-17 | Interpace Diagnostics Corporation | Methods for measuring carcinoembryonic antigen |
| US11060145B2 (en) | 2013-03-13 | 2021-07-13 | Sequenom, Inc. | Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus |
| US10091984B2 (en) | 2013-07-24 | 2018-10-09 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
| EP3736344A1 (de) | 2014-03-13 | 2020-11-11 | Sequenom, Inc. | Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen |
| WO2016001411A1 (en) | 2014-07-03 | 2016-01-07 | Multiplicom N.V. | Methods for non-invasive detection of transplant health or rejection |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| WO2018022991A1 (en) | 2016-07-29 | 2018-02-01 | Streck, Inc. | Suspension composition for hematology analysis control |
| WO2018064486A1 (en) | 2016-09-29 | 2018-04-05 | Counsyl, Inc. | Noninvasive prenatal screening using dynamic iterative depth optimization |
| CN115119829B (zh) | 2017-10-19 | 2024-07-12 | 斯特雷克股份有限公司 | 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物 |
| EP3802857A4 (de) * | 2018-06-07 | 2022-03-09 | BioFire Diagnostics, LLC | Schnelle thermocycling-verfahren |
| US11965217B2 (en) * | 2020-07-21 | 2024-04-23 | Delta Electronics, Inc. | Method and kit for detecting Mycobacterium tuberculosis |
| US20240018585A1 (en) * | 2020-12-15 | 2024-01-18 | Gateway Genomics, Llc | Methods, compositions, and devices for the rapid determination of fetal sex |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5541331A (en) | 1991-04-30 | 1996-07-30 | Reilly Industries, Inc. | Processes for producing α-pyridyl carbinols |
| US6020124A (en) * | 1992-04-27 | 2000-02-01 | Trustees Of Dartmouth College | Detection of soluble gene sequences in biological fluids |
| ATE198358T1 (de) | 1992-04-27 | 2001-01-15 | Dartmouth College | Detektion von gensequenzen in biologischen flüssigkeiten |
| US5614402A (en) | 1992-12-07 | 1997-03-25 | Third Wave Technologies, Inc. | 5' nucleases derived from thermostable DNA polymerase |
| US5541311A (en) | 1992-12-07 | 1996-07-30 | Third Wave Technologies, Inc. | Nucleic acid encoding synthesis-deficient thermostable DNA polymerase |
| WO1997006819A1 (en) * | 1995-08-15 | 1997-02-27 | Alteon Inc. | Compositions and methods for elmination of advanced glycosylation endproducts (in vivo) |
| DE19540222A1 (de) * | 1995-10-18 | 1997-04-24 | Horst Dr Schlechte | Verfahren und Vorrichtung zur Gewinnung Personen- und Krankheits-spezifischer Nucleinsäure-Sequenz-Daten |
| ATE414793T1 (de) | 1996-01-24 | 2008-12-15 | Third Wave Tech Inc | Invasive spaltung von nukleinsäuren |
-
1998
- 1998-05-29 US US09/230,704 patent/US6251638B1/en not_active Expired - Lifetime
- 1998-05-29 DK DK05077010.6T patent/DK1634966T3/da active
- 1998-05-29 EP EP98924998A patent/EP0920539B9/de not_active Expired - Lifetime
- 1998-05-29 DE DE69833856T patent/DE69833856T2/de not_active Expired - Lifetime
- 1998-05-29 AU AU77039/98A patent/AU7703998A/en not_active Abandoned
- 1998-05-29 WO PCT/US1998/010965 patent/WO1998054364A1/en not_active Ceased
- 1998-05-29 ES ES10161334T patent/ES2389055T3/es not_active Expired - Lifetime
- 1998-05-29 AT AT10161334T patent/ATE557103T1/de active
- 1998-05-29 DE DE69841989T patent/DE69841989D1/de not_active Expired - Lifetime
- 1998-05-29 DK DK10161334.7T patent/DK2216416T3/da active
- 1998-05-29 EP EP10161334A patent/EP2216416B1/de not_active Expired - Lifetime
- 1998-05-29 AT AT05077010T patent/ATE486958T1/de active
- 1998-05-29 ES ES98924998T patent/ES2260837T3/es not_active Expired - Lifetime
- 1998-05-29 DK DK98924998T patent/DK0920539T3/da active
- 1998-05-29 PT PT10161334T patent/PT2216416E/pt unknown
- 1998-05-29 AT AT98924998T patent/ATE320505T1/de active
- 1998-05-29 ES ES05077010T patent/ES2355631T3/es not_active Expired - Lifetime
- 1998-05-29 EP EP05077010A patent/EP1634966B1/de not_active Expired - Lifetime
-
2000
- 2000-07-03 US US09/609,162 patent/US6287820B1/en not_active Expired - Lifetime
-
2012
- 2012-08-08 CY CY20121100714T patent/CY1113124T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1634966T3 (da) | 2011-02-07 |
| EP1634966B1 (de) | 2010-11-03 |
| ATE557103T1 (de) | 2012-05-15 |
| ES2260837T3 (es) | 2006-11-01 |
| ES2389055T3 (es) | 2012-10-22 |
| EP0920539A1 (de) | 1999-06-09 |
| AU7703998A (en) | 1998-12-30 |
| EP2216416B1 (de) | 2012-05-09 |
| US6251638B1 (en) | 2001-06-26 |
| HK1088363A1 (en) | 2006-11-03 |
| DE69833856T2 (de) | 2006-11-23 |
| US6287820B1 (en) | 2001-09-11 |
| DK2216416T3 (da) | 2012-08-27 |
| EP1634966A2 (de) | 2006-03-15 |
| EP0920539B9 (de) | 2006-08-02 |
| ATE320505T1 (de) | 2006-04-15 |
| PT2216416E (pt) | 2012-08-16 |
| EP2216416A1 (de) | 2010-08-11 |
| EP1634966A3 (de) | 2006-06-21 |
| ES2355631T3 (es) | 2011-03-29 |
| EP0920539A4 (de) | 2004-06-09 |
| WO1998054364A1 (en) | 1998-12-03 |
| EP0920539B1 (de) | 2006-03-15 |
| CY1113124T1 (el) | 2016-04-13 |
| DE69833856D1 (de) | 2006-05-11 |
| DE69841989D1 (de) | 2010-12-16 |
| DK0920539T3 (da) | 2006-07-24 |
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