ATE48850T1 - Spezifische jodierung von nukleinsaeure. - Google Patents

Spezifische jodierung von nukleinsaeure.

Info

Publication number
ATE48850T1
ATE48850T1 AT86103106T AT86103106T ATE48850T1 AT E48850 T1 ATE48850 T1 AT E48850T1 AT 86103106 T AT86103106 T AT 86103106T AT 86103106 T AT86103106 T AT 86103106T AT E48850 T1 ATE48850 T1 AT E48850T1
Authority
AT
Austria
Prior art keywords
nucleic acid
iodation
specific
iodinatable
residue
Prior art date
Application number
AT86103106T
Other languages
English (en)
Inventor
Nanibhushan Dattagupta
William Dr Knowles
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Application granted granted Critical
Publication of ATE48850T1 publication Critical patent/ATE48850T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT86103106T 1985-03-21 1986-03-08 Spezifische jodierung von nukleinsaeure. ATE48850T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71430685A 1985-03-21 1985-03-21
EP86103106A EP0198207B1 (de) 1985-03-21 1986-03-08 Spezifische Jodierung von Nukleinsäure

Publications (1)

Publication Number Publication Date
ATE48850T1 true ATE48850T1 (de) 1990-01-15

Family

ID=24869509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86103106T ATE48850T1 (de) 1985-03-21 1986-03-08 Spezifische jodierung von nukleinsaeure.

Country Status (4)

Country Link
EP (1) EP0198207B1 (de)
JP (1) JPS61240162A (de)
AT (1) ATE48850T1 (de)
DE (1) DE3667669D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948882A (en) * 1983-02-22 1990-08-14 Syngene, Inc. Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
WO1989006701A1 (en) * 1988-01-25 1989-07-27 Microprobe Corporation Thiol-reactive oligonucleotide intermediates and processes for conjugation of oligonucleotides with enzymes
US5849482A (en) * 1988-09-28 1998-12-15 Epoch Pharmaceuticals, Inc. Crosslinking oligonucleotides
USRE38416E1 (en) 1988-09-28 2004-02-03 Epoch Biosciences, Inc. Cross-linking oligonucleotides
US5824796A (en) * 1988-09-28 1998-10-20 Epoch Pharmaceuticals, Inc. Cross-linking oligonucleotides
WO1990014353A1 (en) * 1989-05-18 1990-11-29 Microprobe Corporation Crosslinking oligonucleotides
JP3124969B2 (ja) * 1989-08-19 2001-01-15 キアゲン・ゲーエムベーハー 温度勾配ゲル電気泳動による混合物成分の分離・検出方法および装置
US5795720A (en) * 1989-08-19 1998-08-18 Qiagen Gmbh Process and device for the separation and detection of components of a mixture of materials by temperature gradient gel electrophoresis
US6136601A (en) * 1991-08-21 2000-10-24 Epoch Pharmaceuticals, Inc. Targeted mutagenesis in living cells using modified oligonucleotides
DE19534046A1 (de) * 1995-09-14 1997-03-20 Biotez Berlin Buch Gmbh Verfahren zur direkten Radiojodierung von Oligonukleotidketten und indirekten Radiojodmarkierung von Peptiden
US5746997A (en) * 1996-10-02 1998-05-05 Epoch Pharmaceuticals, Inc. Radiohalogenation of oligonucleotides via trialkylstannylaryl conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310675A (en) * 1976-09-29 1982-01-12 Becton Dickinson & Company Monoradioiodinated imidazole derivatives
US4397779A (en) * 1978-08-09 1983-08-09 Baxter Travenol Laboratories, Inc. Preparation of xanthine tracers
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
AU596068B2 (en) * 1983-02-22 1990-04-26 Syngene, Inc. Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis

Also Published As

Publication number Publication date
DE3667669D1 (de) 1990-01-25
JPS61240162A (ja) 1986-10-25
EP0198207A1 (de) 1986-10-22
EP0198207B1 (de) 1989-12-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee