ATE488772T1 - Biomarker zur beurteilung der leberfunktion - Google Patents

Biomarker zur beurteilung der leberfunktion

Info

Publication number: ATE488772T1
Authority: AT; Austria
Prior art keywords: liver function; biomarrkers; assessing liver; individual; assessing
Prior art date: 2006-09-07

Application number

AT07804163T

Other languages

English (en)

Inventor

Rajiv Jalan

Rajeshwar P Mookerjee

Nathan Davies

Original Assignee

Ucl Business Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-07

Filing date

2007-09-07

Publication date

2010-12-15

2007-09-07 Application filed by Ucl Business Plc filed Critical Ucl Business Plc

2010-12-15 Application granted granted Critical

2010-12-15 Publication of ATE488772T1 publication Critical patent/ATE488772T1/de

Links

230000003908 liver function Effects 0.000 title abstract 3
108010023015 ischemia-modified albumin Proteins 0.000 abstract 2
NTNWOCRCBQPEKQ-UHFFFAOYSA-N 2-azaniumyl-5-[(n'-methylcarbamimidoyl)amino]pentanoate Chemical compound CN=C(N)NCCCC(N)C(O)=O NTNWOCRCBQPEKQ-UHFFFAOYSA-N 0.000 abstract 1
108010088751 Albumins Proteins 0.000 abstract 1
102000009027 Albumins Human genes 0.000 abstract 1
YDGMGEXADBMOMJ-LURJTMIESA-N N(g)-dimethylarginine Chemical compound CN(C)C(\N)=N\CCC[C@H](N)C(O)=O YDGMGEXADBMOMJ-LURJTMIESA-N 0.000 abstract 1
YDGMGEXADBMOMJ-UHFFFAOYSA-N asymmetrical dimethylarginine Natural products CN(C)C(N)=NCCCC(N)C(O)=O YDGMGEXADBMOMJ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
- G01N2333/765—Serum albumin, e.g. HSA
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
- G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Immunology (AREA)
Cell Biology (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring And Recording Apparatus For Diagnosis (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

AT07804163T 2006-09-07 2007-09-07 Biomarker zur beurteilung der leberfunktion ATE488772T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0617581.4A GB0617581D0 (en)	2006-09-07	2006-09-07	Biomarkers for assessing liver function
PCT/GB2007/003362 WO2008029145A1 (en)	2006-09-07	2007-09-07	Biqmarkers for assessing liver function

Publications (1)

Publication Number	Publication Date
ATE488772T1 true ATE488772T1 (de)	2010-12-15

Family

ID=37232490

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07804163T ATE488772T1 (de)	2006-09-07	2007-09-07	Biomarker zur beurteilung der leberfunktion

Country Status (16)

Country	Link
US (1)	US8455220B2 (de)
EP (1)	EP2059817B1 (de)
JP (1)	JP4949473B2 (de)
KR (1)	KR20090083335A (de)
AT (1)	ATE488772T1 (de)
AU (1)	AU2007293302A1 (de)
CA (1)	CA2662597A1 (de)
DE (1)	DE602007010644D1 (de)
EA (1)	EA200970256A1 (de)
ES (1)	ES2353835T3 (de)
GB (1)	GB0617581D0 (de)
IL (1)	IL197271A0 (de)
MX (1)	MX2009002378A (de)
NO (1)	NO20090993L (de)
WO (1)	WO2008029145A1 (de)
ZA (1)	ZA200901432B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2823349T3 (es)	2011-05-31	2021-05-06	Univ Colorado Regents	Procedimiento para evaluación de la función hepática y el flujo sanguíneo portal
CA2891281C (en)	2012-11-12	2023-11-28	The Regents Of The University Of Colorado, A Body Corporate	Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis
WO2014190170A1 (en) *	2013-05-22	2014-11-27	The Regents Of The University Of California	Biomarker composite test for hepatic vein pressure gradient and cirrhosis treatment
US10335452B2 (en) *	2014-10-24	2019-07-02	Mallinckrodt Hospital Products IP Limited	Method of treating patients with hepatorenal syndrome type 1
CN105181692A (zh) *	2015-09-30	2015-12-23	山东博科生物产业有限公司	一种缺血修饰白蛋白比色法检测试剂盒
ES2761266T3 (es) *	2015-11-10	2020-05-19	Inst Nat Sante Rech Med	Métodos para predicción del tiempo de supervivencia de los pacientes con cirrosis alcohólica descompensada
US20220018852A1 (en) *	2018-11-20	2022-01-20	Inserm (Institute National De Ka Santé Et De La Recherche Médicale)	Methods and kits for detecting liver dysfunction in a subject
CN121331222B (zh) *	2025-12-15	2026-03-10	北京大学	基于蛋白质组的慢性肝脏疾病发病预测的蛋白组合、预测模型及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997034605A1 (en) *	1996-03-21	1997-09-25	Mayo Foundation For Medical Education And Research	Use of nicotine to treat liver disease
CA2415174A1 (en) *	2000-07-06	2002-01-17	Thomas W. Bell	Methods and kits for the detection of arginine compounds
WO2003046538A1 (en) *	2001-11-26	2003-06-05	Ischemia Technologies, Inc.	Electrochemical detection of ischemia
AU2003261424A1 (en) *	2002-08-06	2004-02-23	Nitromed, Inc.	Nitrosated and/or nitrosylated ursodeoxycholic acid compounds, compositions and methods of use
AU2003290784A1 (en)	2002-11-15	2004-06-15	The Board Of Trustees Of The Leland Stanford Junior University	Methods for detecting asymmetric dimethylarginine in a biological sample
WO2005039598A1 (en)	2003-10-24	2005-05-06	Intermune, Inc.	Method of treating alcoholic liver disease
DE10351238A1 (de) *	2003-11-03	2005-06-02	Roche Diagnostics Gmbh	Diagnosestellung von akuten myokardialen, ischämischen Erkrankungen durch Kombination von Markern

2006
- 2006-09-07 GB GBGB0617581.4A patent/GB0617581D0/en not_active Ceased
2007
- 2007-09-07 US US12/440,170 patent/US8455220B2/en active Active
- 2007-09-07 AT AT07804163T patent/ATE488772T1/de not_active IP Right Cessation
- 2007-09-07 WO PCT/GB2007/003362 patent/WO2008029145A1/en not_active Ceased
- 2007-09-07 CA CA002662597A patent/CA2662597A1/en not_active Abandoned
- 2007-09-07 ZA ZA200901432A patent/ZA200901432B/xx unknown
- 2007-09-07 JP JP2009527200A patent/JP4949473B2/ja active Active
- 2007-09-07 MX MX2009002378A patent/MX2009002378A/es not_active Application Discontinuation
- 2007-09-07 EP EP07804163A patent/EP2059817B1/de active Active
- 2007-09-07 EA EA200970256A patent/EA200970256A1/ru unknown
- 2007-09-07 KR KR1020097007160A patent/KR20090083335A/ko not_active Ceased
- 2007-09-07 DE DE602007010644T patent/DE602007010644D1/de active Active
- 2007-09-07 ES ES07804163T patent/ES2353835T3/es active Active
- 2007-09-07 AU AU2007293302A patent/AU2007293302A1/en not_active Abandoned
2009
- 2009-02-26 IL IL197271A patent/IL197271A0/en unknown
- 2009-03-05 NO NO20090993A patent/NO20090993L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2008029145A1 (en)	2008-03-13
EP2059817B1 (de)	2010-11-17
JP2010502979A (ja)	2010-01-28
GB0617581D0 (en)	2006-10-18
ZA200901432B (en)	2010-06-30
JP4949473B2 (ja)	2012-06-06
US8455220B2 (en)	2013-06-04
AU2007293302A1 (en)	2008-03-13
DE602007010644D1 (de)	2010-12-30
EP2059817A1 (de)	2009-05-20
US20090280519A1 (en)	2009-11-12
EA200970256A1 (ru)	2009-08-28
CA2662597A1 (en)	2008-03-13
KR20090083335A (ko)	2009-08-03
NO20090993L (no)	2009-04-03
ES2353835T3 (es)	2011-03-07
IL197271A0 (en)	2009-12-24
MX2009002378A (es)	2009-03-20

Legal Events

Date	Code	Title	Description
2011-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE488772T1 (de)	2010-12-15	Biomarker zur beurteilung der leberfunktion
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