ATE489380T1 - Hydratformen von amg706 - Google Patents
Hydratformen von amg706Info
- Publication number
- ATE489380T1 ATE489380T1 AT07717053T AT07717053T ATE489380T1 AT E489380 T1 ATE489380 T1 AT E489380T1 AT 07717053 T AT07717053 T AT 07717053T AT 07717053 T AT07717053 T AT 07717053T AT E489380 T1 ATE489380 T1 AT E489380T1
- Authority
- AT
- Austria
- Prior art keywords
- amg
- amg706
- angiogenic
- hydrate forms
- drug substance
- Prior art date
Links
- RAHBGWKEPAQNFF-UHFFFAOYSA-N motesanib Chemical compound C=1C=C2C(C)(C)CNC2=CC=1NC(=O)C1=CC=CN=C1NCC1=CC=NC=C1 RAHBGWKEPAQNFF-UHFFFAOYSA-N 0.000 title abstract 7
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 2
- 229940088679 drug related substance Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- CKRORYDHXIRZCH-UHFFFAOYSA-N phosphoric acid;dihydrate Chemical compound O.O.OP(O)(O)=O CKRORYDHXIRZCH-UHFFFAOYSA-N 0.000 abstract 2
- 239000004037 angiogenesis inhibitor Substances 0.000 abstract 1
- 230000001772 anti-angiogenic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- TWHXWYVOWJCXSI-UHFFFAOYSA-N phosphoric acid;hydrate Chemical group O.OP(O)(O)=O TWHXWYVOWJCXSI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Lubricants (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77239706P | 2006-02-10 | 2006-02-10 | |
| PCT/US2007/002182 WO2007092178A1 (en) | 2006-02-10 | 2007-01-26 | Hydrate forms of amg706 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489380T1 true ATE489380T1 (de) | 2010-12-15 |
Family
ID=38003498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07717053T ATE489380T1 (de) | 2006-02-10 | 2007-01-26 | Hydratformen von amg706 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7989631B2 (de) |
| EP (1) | EP1987023B1 (de) |
| JP (2) | JP2009526050A (de) |
| AT (1) | ATE489380T1 (de) |
| AU (1) | AU2007212696B2 (de) |
| CA (1) | CA2641713C (de) |
| DE (1) | DE602007010734D1 (de) |
| ES (1) | ES2353482T3 (de) |
| WO (1) | WO2007092178A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2353482T3 (es) * | 2006-02-10 | 2011-03-02 | Amgen, Inc | Formas hidrato de amg706. |
| MX2010012290A (es) * | 2008-05-14 | 2011-02-21 | Amgen Inc | Combinaciones de inhibidores del receptor del factor de crecimiento endotelial vascular e inhibidores del factor de crecimiento de hepatocito para el tratamiento de cancer. |
| WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| EP2968113B8 (de) | 2013-03-14 | 2020-10-28 | Forsight Vision4, Inc. | Systeme zur verzögerten intraokularen abgabe schwerlöslicher verbindungen aus einem implantat mit einem portabgabesystem |
| MX2017001818A (es) | 2014-08-08 | 2017-05-30 | Forsight Vision4 Inc | Formulaciones estables y solubles de inhibidores de receptor de quinasa tirosina y metodos de preparacion de los mismos. |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797388A (en) * | 1984-05-21 | 1989-01-10 | Cetus Corporation | Pharmaceutical compositions with galactitol as carrier |
| JP2762522B2 (ja) | 1989-03-06 | 1998-06-04 | 藤沢薬品工業株式会社 | 血管新生阻害剤 |
| US5112946A (en) | 1989-07-06 | 1992-05-12 | Repligen Corporation | Modified pf4 compositions and methods of use |
| CA2101571A1 (en) * | 1992-09-08 | 1994-03-09 | Elizabeth A. Garofalo | Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof |
| USRE39706E1 (en) * | 1993-01-15 | 2007-06-26 | Leo Pharma A/S | Crystalline form of a vitamin D analogue |
| US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
| DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| CO4950519A1 (es) | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
| JP2002505330A (ja) | 1998-03-04 | 2002-02-19 | ブリストル−マイヤーズ スクイブ カンパニー | ヘテロシクロ−置換イミダゾピラジン・たんぱくチロシンキナーゼ抑制剤 |
| IL139934A (en) | 1998-05-29 | 2007-10-31 | Sugen Inc | History 2 - Indulinone converted to pyrrole and pharmaceutical preparations containing them |
| UA60365C2 (uk) * | 1998-06-04 | 2003-10-15 | Пфайзер Продактс Інк. | Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця |
| WO2000002871A1 (en) | 1998-07-10 | 2000-01-20 | Merck & Co., Inc. | Novel angiogenesis inhibitors |
| CA2341409A1 (en) | 1998-08-31 | 2000-03-09 | Merck And Co., Inc. | Novel angiogenesis inhibitors |
| PT1165085E (pt) | 1999-03-30 | 2006-10-31 | Novartis Ag | Derivados de ftalazina para tratar doencas inflamatorias |
| PL203782B1 (pl) | 1999-11-05 | 2009-11-30 | Astrazeneca Ab | Pochodne chinazoliny,sposoby ich wytwarzania,ich kompozycje farmaceutyczne oraz ich zastosowania |
| PT1233943E (pt) | 1999-11-24 | 2011-09-01 | Sugen Inc | Formulações para agentes farmacêuticos ionizáveis como ácidos livres ou bases livres |
| ATE430742T1 (de) | 2000-12-21 | 2009-05-15 | Smithkline Beecham Corp | Pyrimidinamine als angiogenesemodulatoren |
| US6878714B2 (en) * | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| US7105682B2 (en) | 2001-01-12 | 2006-09-12 | Amgen Inc. | Substituted amine derivatives and methods of use |
| US7102009B2 (en) | 2001-01-12 | 2006-09-05 | Amgen Inc. | Substituted amine derivatives and methods of use |
| US20020147198A1 (en) | 2001-01-12 | 2002-10-10 | Guoqing Chen | Substituted arylamine derivatives and methods of use |
| US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
| US7307088B2 (en) | 2002-07-09 | 2007-12-11 | Amgen Inc. | Substituted anthranilic amide derivatives and methods of use |
| TWI329112B (en) | 2002-07-19 | 2010-08-21 | Bristol Myers Squibb Co | Novel inhibitors of kinases |
| ES2353482T3 (es) * | 2006-02-10 | 2011-03-02 | Amgen, Inc | Formas hidrato de amg706. |
-
2007
- 2007-01-26 ES ES07717053T patent/ES2353482T3/es active Active
- 2007-01-26 CA CA2641713A patent/CA2641713C/en not_active Expired - Fee Related
- 2007-01-26 AT AT07717053T patent/ATE489380T1/de not_active IP Right Cessation
- 2007-01-26 AU AU2007212696A patent/AU2007212696B2/en not_active Ceased
- 2007-01-26 EP EP07717053A patent/EP1987023B1/de active Active
- 2007-01-26 WO PCT/US2007/002182 patent/WO2007092178A1/en not_active Ceased
- 2007-01-26 US US11/627,803 patent/US7989631B2/en not_active Expired - Fee Related
- 2007-01-26 JP JP2008554256A patent/JP2009526050A/ja active Pending
- 2007-01-26 DE DE602007010734T patent/DE602007010734D1/de active Active
-
2013
- 2013-10-17 JP JP2013216046A patent/JP2014055143A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007092178A1 (en) | 2007-08-16 |
| JP2009526050A (ja) | 2009-07-16 |
| US20080039501A1 (en) | 2008-02-14 |
| EP1987023A1 (de) | 2008-11-05 |
| AU2007212696A1 (en) | 2007-08-16 |
| AU2007212696B2 (en) | 2011-05-19 |
| US7989631B2 (en) | 2011-08-02 |
| CA2641713A1 (en) | 2007-08-16 |
| CA2641713C (en) | 2011-11-22 |
| ES2353482T3 (es) | 2011-03-02 |
| JP2014055143A (ja) | 2014-03-27 |
| DE602007010734D1 (de) | 2011-01-05 |
| EP1987023B1 (de) | 2010-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |