ATE48991T1 - 11-substituierte-16-phenoxy und 16phenoxysubstituierte prostatriensaeurederivate. - Google Patents

11-substituierte-16-phenoxy und 16phenoxysubstituierte prostatriensaeurederivate.

Info

Publication number: ATE48991T1
Authority: AT; Austria
Prior art keywords: substituted; hydrogen; prostatric; 16phenoxy; phenoxy
Prior art date: 1984-07-31

Application number

AT85109580T

Other languages

English (en)

Inventor

Gary F Cooper

John H Fried

David Waterbury

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-31

Filing date

1985-07-30

Publication date

1990-01-15

1985-07-30 Application filed by Syntex Inc filed Critical Syntex Inc

1990-01-15 Application granted granted Critical

1990-01-15 Publication of ATE48991T1 publication Critical patent/ATE48991T1/de

Links

239000002253 acid Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
125000001475 halogen functional group Chemical group 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Ophthalmology & Optometry (AREA)
Pulmonology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT85109580T 1984-07-31 1985-07-30 11-substituierte-16-phenoxy und 16phenoxysubstituierte prostatriensaeurederivate. ATE48991T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US63597084A	1984-07-31	1984-07-31
EP85109580A EP0170258B1 (de)	1984-07-31	1985-07-30	11-Substituierte-16-phenoxy und 16-phenoxysubstituierte Prostatriensäurederivate

Publications (1)

Publication Number	Publication Date
ATE48991T1 true ATE48991T1 (de)	1990-01-15

Family

ID=24549856

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85109580T ATE48991T1 (de)	1984-07-31	1985-07-30	11-substituierte-16-phenoxy und 16phenoxysubstituierte prostatriensaeurederivate.

Country Status (10)

Country	Link
EP (1)	EP0170258B1 (de)
JP (1)	JPS6147459A (de)
AT (1)	ATE48991T1 (de)
AU (1)	AU573018B2 (de)
DE (1)	DE3574968D1 (de)
DK (1)	DK346085A (de)
ES (1)	ES8607921A1 (de)
HU (1)	HU196174B (de)
NZ (1)	NZ212914A (de)
ZA (1)	ZA855740B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4600785A (en) *	1983-12-22	1986-07-15	Syntex (U.S.A.) Inc.	Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4912235A (en) *	1983-12-22	1990-03-27	Syntex (U.S.A.) Inc.	Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers
US4804787A (en) *	1983-12-22	1989-02-14	Syntex (U.S.A.) Inc.	Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4618696A (en) *	1984-07-31	1986-10-21	Syntex (U.S.A.) Inc.	9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
US5057621A (en) *	1984-07-31	1991-10-15	Syntex (U.S.A.) Inc.	11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
NO163485C (no) *	1984-10-09	1990-06-06	Syntex Inc	Mellomprodukter for fremstilling av 16-fenoksy- og 16-substituerte fenoksy-prostatriensyrederivater og fremgangsmaate ved fremstilling av mellomproduktene.
EP0186181A3 (de) *	1984-12-24	1986-08-13	Syntex (U.S.A.) Inc.	Anwendungen für Enprostil
US5236907A (en) *	1988-10-01	1993-08-17	R-Tech Ueno Ltd.	Ocular hypotensive agents
US6420422B1 (en)	1987-09-18	2002-07-16	Sucampo Pharmaceuticals, Inc.	Ocular hypotensive agents
ES2317964T5 (es) *	1988-09-06	2015-02-20	Pfizer Health Ab	Derivado de prostaglandina-F2alfa para el tratamiento de glaucoma o hipertensión ocular
US6187813B1 (en)	1990-04-10	2001-02-13	Pharmacia & Upjohn Aktiebolag	Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5321128A (en) *	1988-09-06	1994-06-14	Kabi Pharmacia Ab	Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
EP1300150A3 (de) *	1988-09-06	2003-05-14	Pharmacia Aktiebolag	Prostaglandin-Derivate zur Behandlung von Glaukom oder Augenüberdruck
US5296504A (en) *	1988-09-06	1994-03-22	Kabi Pharmacia	Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
KR100224951B1 (ko) *	1990-03-08	1999-10-15	시오노 요시히코	15-데옥시프로스타글란딘유도체
CA2138181A1 (en) *	1993-12-15	1995-06-16	Verney L. Sallee	Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
DE69823852T2 (de)	1997-02-04	2005-05-19	Johnstone, Murray A., Seattle	Verfahren zur förderung des haarwuchses und entwicklung des haarsystems
AU2211700A (en) *	1998-12-24	2000-07-31	Alcon Laboratories, Inc.	Prostaglandin e agonists for treatment of glaucoma
WO2000051980A1 (en)	1999-03-05	2000-09-08	The Procter & Gamble Company	C16 unsaturated fp-selective prostaglandins analogs
US20020013294A1 (en)	2000-03-31	2002-01-31	Delong Mitchell Anthony	Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en)	2000-03-31	2002-03-28	Delong Mitchell Anthony	Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en)	2000-03-31	2002-11-21	Delong Michell Anthony	Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US8758733B2 (en)	2002-02-04	2014-06-24	Allergan, Inc.	Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US7351404B2 (en)	2002-02-04	2008-04-01	Allergan, Inc.	Method of enhancing hair growth
US9216183B2 (en)	2002-02-04	2015-12-22	Allergan, Inc.	Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
DE60334905D1 (de) *	2002-06-06	2010-12-23	Merck Frosst Canada Ltd	1,5-disubstituierte pyrrolid-2-on-derivate zur verwendung als ep4 rezeptor agonisten zur behandlung von augenkrankheiten wie z.b. glaukom
US7642370B2 (en)	2006-08-07	2010-01-05	Daiichi Fine Chemical Co., Ltd.	Method for preparing prostaglandin derivative
US8623918B2 (en)	2008-10-29	2014-01-07	Novaer Holdings, Inc.	Amino acid salts of prostaglandins
US8722739B2 (en)	2008-10-29	2014-05-13	Novaer Holdings, Inc.	Amino acid salts of prostaglandins
US9149484B2 (en)	2009-11-09	2015-10-06	Allergan, Inc.	Compositions and methods for stimulating hair growth
NZ628266A (en)	2009-11-09	2016-02-26	Allergan Inc	Compositions and methods for stimulating hair growth
US8859616B2 (en)	2011-01-21	2014-10-14	Allergan, Inc.	Compounds and methods for enhancing hair growth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3989744A (en) *	1973-07-30	1976-11-02	Miles Laboratories, Inc.	11-Substitute d-11-desoxy-pge analogues
US4178457A (en) *	1978-07-10	1979-12-11	Syntex (U.S.A.) Inc.	(dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof
US4618696A (en) *	1984-07-31	1986-10-21	Syntex (U.S.A.) Inc.	9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates

1985
- 1985-07-30 AU AU45620/85A patent/AU573018B2/en not_active Ceased
- 1985-07-30 HU HU852917A patent/HU196174B/hu not_active IP Right Cessation
- 1985-07-30 AT AT85109580T patent/ATE48991T1/de not_active IP Right Cessation
- 1985-07-30 EP EP85109580A patent/EP0170258B1/de not_active Expired
- 1985-07-30 ZA ZA855740A patent/ZA855740B/xx unknown
- 1985-07-30 NZ NZ212914A patent/NZ212914A/xx unknown
- 1985-07-30 JP JP60169653A patent/JPS6147459A/ja active Pending
- 1985-07-30 DK DK346085A patent/DK346085A/da not_active Application Discontinuation
- 1985-07-30 DE DE8585109580T patent/DE3574968D1/de not_active Expired - Lifetime
- 1985-07-30 ES ES545700A patent/ES8607921A1/es not_active Expired

Also Published As

Publication number	Publication date
DK346085D0 (da)	1985-07-30
HU196174B (en)	1988-10-28
AU4562085A (en)	1986-02-06
AU573018B2 (en)	1988-05-26
ZA855740B (en)	1987-03-25
EP0170258A3 (en)	1986-09-10
HUT38309A (en)	1986-05-28
DK346085A (da)	1986-02-01
DE3574968D1 (de)	1990-02-01
EP0170258A2 (de)	1986-02-05
EP0170258B1 (de)	1989-12-27
ES8607921A1 (es)	1986-06-16
JPS6147459A (ja)	1986-03-07
ES545700A0 (es)	1986-06-16
NZ212914A (en)	1988-08-30

Legal Events

Date	Code	Title	Description
1990-05-15	UEP	Publication of translation of european patent specification
1991-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3574968D1 (de)	1990-02-01	11-substituierte-16-phenoxy und 16-phenoxysubstituierte prostatriensaeurederivate.
ATE45354T1 (de)	1989-08-15	Chinoloncarbonsaeurederivate.
PH23448A (en)	1989-08-07	Quinoline compounds
ES8504718A1 (es)	1985-05-01	Un metodo para preparar derivados de 4-hidroxi-2-quinolona.
FI872555A0 (fi)	1987-06-08	Antiallergiska och antiinflammatoriska aemnen.
ES2046229T3 (es)	1994-02-01	Composicion antiulcerosa.
GR3003776T3 (de)	1993-03-16
NZ220338A (en)	1989-09-27	2-benzoyl-1,3,5-cyclohexanetrione derivatives and herbicidal compositions
NO903514D0 (no)	1990-08-09	Imidazolderivat og fremgangsmaate til dets fremstilling.
ATE53833T1 (de)	1990-06-15	Derivate des phenylacetanilids.
SG136194G (en)	1995-04-28	Novel benzoxazolone compounds and the use thereof as microbicides
ES2077697T3 (es)	1995-12-01	Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
ATE52514T1 (de)	1990-05-15	S-aralkyltrithiophosphonat-insektizide.