ATE491032T1 - Polypeptide mit nukleinsäurebindender aktivität - Google Patents

Polypeptide mit nukleinsäurebindender aktivität

Info

Publication number
ATE491032T1
ATE491032T1 AT06717485T AT06717485T ATE491032T1 AT E491032 T1 ATE491032 T1 AT E491032T1 AT 06717485 T AT06717485 T AT 06717485T AT 06717485 T AT06717485 T AT 06717485T AT E491032 T1 ATE491032 T1 AT E491032T1
Authority
AT
Austria
Prior art keywords
nucleic acid
methods
binding activity
acid binding
polypeptides
Prior art date
Application number
AT06717485T
Other languages
English (en)
Inventor
Patrick Martin
David Simpson
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Application granted granted Critical
Publication of ATE491032T1 publication Critical patent/ATE491032T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT06717485T 2005-01-06 2006-01-06 Polypeptide mit nukleinsäurebindender aktivität ATE491032T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64198705P 2005-01-06 2005-01-06
PCT/US2006/000292 WO2006074288A2 (en) 2005-01-06 2006-01-06 Polypeptides having nucleic acid binding activity

Publications (1)

Publication Number Publication Date
ATE491032T1 true ATE491032T1 (de) 2010-12-15

Family

ID=36648169

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06717485T ATE491032T1 (de) 2005-01-06 2006-01-06 Polypeptide mit nukleinsäurebindender aktivität

Country Status (6)

Country Link
US (3) US8349600B2 (de)
EP (1) EP1833969B1 (de)
AT (1) ATE491032T1 (de)
AU (1) AU2006203970A1 (de)
DE (1) DE602006018701D1 (de)
WO (1) WO2006074288A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8349600B2 (en) 2005-01-06 2013-01-08 Applied Biosystems, Llc Polypeptides having nucleic acid binding activity
EP2393933A4 (de) * 2009-02-04 2013-05-01 Lucigen Corp Rna und dna kopierende enzyme
CN102392000A (zh) * 2011-11-07 2012-03-28 李志茹 一种耐高温Pyrolobus聚合酶及其高效表达质粒和应用
WO2017121836A1 (en) 2016-01-15 2017-07-20 Thermo Fisher Scientific Baltics Uab Thermophilic dna polymerase mutants
WO2017121843A1 (en) 2016-01-15 2017-07-20 Thermo Fisher Scientific Baltics Uab Antibodies that bind thermophilic dna polymerases
EP3580351A1 (de) 2017-02-13 2019-12-18 Qiagen Sciences, LLC Polymeraseenzym aus 9°n
EP3645710A1 (de) 2017-06-26 2020-05-06 Thermo Fisher Scientific Baltics Uab Thermophile dna-polymerase-mutanten
CN114574464B (zh) * 2022-05-05 2022-10-14 南京巨匠生物科技有限公司 高保真dna聚合酶突变体及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030228616A1 (en) * 1999-10-29 2003-12-11 Stratagene DNA polymerase mutants with reverse transcriptase activity
US6627424B1 (en) * 2000-05-26 2003-09-30 Mj Bioworks, Inc. Nucleic acid modifying enzymes
EP1456394B2 (de) 2001-11-28 2011-04-27 Bio-Rad Laboratories, Inc. Verfahren zur verwendung verbesserter polymerasen
EP1558757A4 (de) 2002-11-01 2006-06-07 Megabase Res Products Gasstrahl-verfahren und gerät für dna-hochgeschwindigkeitsamplifikation
US8349600B2 (en) 2005-01-06 2013-01-08 Applied Biosystems, Llc Polypeptides having nucleic acid binding activity

Also Published As

Publication number Publication date
US20060223157A1 (en) 2006-10-05
EP1833969A2 (de) 2007-09-19
WO2006074288A2 (en) 2006-07-13
US20130164817A1 (en) 2013-06-27
US9212352B2 (en) 2015-12-15
EP1833969B1 (de) 2010-12-08
WO2006074288A3 (en) 2007-03-08
DE602006018701D1 (de) 2011-01-20
US20160122393A1 (en) 2016-05-05
US8349600B2 (en) 2013-01-08
AU2006203970A1 (en) 2006-07-13

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