ATE491478T1 - Gelenkeoberflächematerialen zur herstellung von medizinische implantate - Google Patents

Gelenkeoberflächematerialen zur herstellung von medizinische implantate

Info

Publication number
ATE491478T1
ATE491478T1 AT06255075T AT06255075T ATE491478T1 AT E491478 T1 ATE491478 T1 AT E491478T1 AT 06255075 T AT06255075 T AT 06255075T AT 06255075 T AT06255075 T AT 06255075T AT E491478 T1 ATE491478 T1 AT E491478T1
Authority
AT
Austria
Prior art keywords
joint surface
surface materials
medical implants
producing medical
agent
Prior art date
Application number
AT06255075T
Other languages
English (en)
Inventor
Richard S King
Mark D Hanes
Original Assignee
Depuy Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Products Inc filed Critical Depuy Products Inc
Application granted granted Critical
Publication of ATE491478T1 publication Critical patent/ATE491478T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethylene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking
    • C08L2312/06—Crosslinking by radiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • External Artificial Organs (AREA)
AT06255075T 2005-09-30 2006-09-29 Gelenkeoberflächematerialen zur herstellung von medizinische implantate ATE491478T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/241,136 US20070077268A1 (en) 2005-09-30 2005-09-30 Hydrophobic carrier modified implants for beneficial agent delivery

Publications (1)

Publication Number Publication Date
ATE491478T1 true ATE491478T1 (de) 2011-01-15

Family

ID=37808480

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06255075T ATE491478T1 (de) 2005-09-30 2006-09-29 Gelenkeoberflächematerialen zur herstellung von medizinische implantate

Country Status (6)

Country Link
US (1) US20070077268A1 (de)
EP (1) EP1779877B1 (de)
AT (1) ATE491478T1 (de)
DE (1) DE602006018845D1 (de)
DK (1) DK1779877T3 (de)
ES (1) ES2356253T3 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2277560B1 (de) * 2005-08-18 2013-10-09 Zimmer GmbH Ultrahochmolekulare Polyethylen-Artikel und Verfahren zur Herstellung von ultrahochmolekularen Polyethylen-Artikeln
EP2150285B1 (de) * 2007-04-10 2012-02-08 Zimmer, Inc. Antioxidans-stabilisiertes vernetztes ultrahochmolekulares polyethylen für anwendungen in medizinprodukten
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
CA2712559C (en) 2008-01-30 2015-03-31 Zimmer, Inc. Orthopedic component of low stiffness
US8133436B2 (en) 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
WO2010057644A1 (en) * 2008-11-20 2010-05-27 Zimmer Gmbh Polyethylene materials
EP2398515B1 (de) * 2009-02-19 2018-09-05 Smith & Nephew Orthopaedics AG Verschleisspartikel mit gutartiger körperreaktion erzeugendes medizinisches implantat
US8933145B2 (en) 2009-02-20 2015-01-13 The General Hospital Corporation High temperature melting
BRPI1013940A2 (pt) 2009-05-04 2016-04-05 Smith & Nephew Inc efeitos sinérgicos da mistura de aditivos múltiplos em uhmwpe
EP2289575B1 (de) * 2009-08-06 2017-07-05 Biotronik VI Patent AG Medizinisches Implantat enthaltend eine antioxidative Substanz
US20110034990A1 (en) * 2009-08-06 2011-02-10 Alexander Borck Biocorrodible implant with active coating
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
WO2015050851A1 (en) 2013-10-01 2015-04-09 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
JP2016536391A (ja) 2013-10-17 2016-11-24 ザ ジェネラル ホスピタル コーポレイション 過酸化物架橋および高温溶融
US10184031B2 (en) 2014-03-12 2019-01-22 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
JP2015006444A (ja) * 2014-09-19 2015-01-15 スミス・アンド・ネフュー・オルソペディクス・アーゲー 良好な身体応答を示す磨耗粒子を生じる医療用インプラント
CA2969751C (en) 2014-12-03 2020-09-22 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
GB201503583D0 (en) * 2015-03-03 2015-04-15 Isis Innovation A method of providing a radio-opaque polymer element
WO2017015571A1 (en) 2015-07-23 2017-01-26 Novaflux, Inc. Implants and constructs including hollow fibers
EP3373990A1 (de) 2015-11-12 2018-09-19 The General Hospital Corporation Verfahren zur herstellung eines therapeutischen polymermaterials
EP3411422A1 (de) 2016-02-05 2018-12-12 The General Hospital Corporation Medikamenteneluierendes polymer aus biologisch abbaubaren polymeren zum auftragen auf die oberfläche von medizinprodukten
AU2017261160A1 (en) * 2016-05-02 2018-11-22 The General Hospital Corporation Implant surfaces for pain control
WO2019046243A2 (en) 2017-08-29 2019-03-07 The General Hospital Corporation UV-INITIATED REACTIONS IN POLYMERIC MATERIALS
CN113289060A (zh) * 2020-05-03 2021-08-24 深圳海思医疗有限公司 组合物及应用、关节植入物型材、关节植入物及制备方法
US11970600B2 (en) 2021-03-31 2024-04-30 The General Hospital Corporation Di-cumyl peroxide crosslinking of UHMWPE

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL262650A (de) * 1960-03-23
US3954927A (en) * 1973-02-05 1976-05-04 Sun Ventures, Inc. Method of making porous objects of ultra high molecular weight polyethylene
US4454612A (en) * 1980-05-07 1984-06-19 Biomet, Inc. Prosthesis formation having solid and porous polymeric components
US4670508A (en) * 1984-01-06 1987-06-02 Mitsui Petrochemical Industries Ltd. Thermoplastic resin composition
US4778601A (en) * 1984-10-09 1988-10-18 Millipore Corporation Microporous membranes of ultrahigh molecular weight polyethylene
US4880843A (en) * 1988-03-28 1989-11-14 Hoechst Celanese Corporation Composition and process for making porous articles from ultra high molecular weight polyethylene
US5275838A (en) * 1990-02-28 1994-01-04 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
JP2957021B2 (ja) * 1991-01-25 1999-10-04 テルモ株式会社 医療用材料および医療用器具ならびに医療用材料の製造方法
US5288818A (en) * 1991-08-20 1994-02-22 Exxon Chemical Patents Inc. Method for separating a water soluble noble metal catalyst from a noble metal catalyzed hydroformylation reaction
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
CH686306A5 (de) * 1993-09-17 1996-02-29 Ciba Geigy Ag 3-Aryl-benzofuranone als Stabilisatoren.
US5593719A (en) * 1994-03-29 1997-01-14 Southwest Research Institute Treatments to reduce frictional wear between components made of ultra-high molecular weight polyethylene and metal alloys
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5594055A (en) * 1995-02-22 1997-01-14 Hoffmann-La Roche Inc. Antioxidant system for polyolefins
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US5721334A (en) * 1996-02-16 1998-02-24 Newyork Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Process for producing ultra-high molecular weight low modulus polyethylene shaped articles via controlled pressure and temperature and compositions and articles produced therefrom
US5844027A (en) * 1996-05-03 1998-12-01 Ciba Specialty Chemicals Corporation Stabilizer composition for thermoplastic materials
EP0935446B1 (de) * 1996-07-09 2007-02-07 Orthopaedic Hospital Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
US6228900B1 (en) * 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5827904A (en) * 1996-09-27 1998-10-27 Hahn; David Medical implant composition
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
EP1028760B1 (de) * 1996-10-15 2004-04-14 Orthopaedic Hospital Verschleissfestes vernetztes polyethylen mit oberflächengradienten
EP0995449A1 (de) * 1998-10-21 2000-04-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
WO2000032248A1 (en) * 1998-11-30 2000-06-08 The Regents Of The University Of California Plasma-assisted surface modification of polymers for medical device applications
SE9900519D0 (sv) * 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6365089B1 (en) * 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant
US6395799B1 (en) * 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
JP4256096B2 (ja) * 2000-04-27 2009-04-22 ザ オーソピーディック ホスピタル 人工関節用の耐酸化性及び耐摩耗性ポリエチレン及び該ポリエチレンの製造方法
US6818172B2 (en) * 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
US7662954B2 (en) * 2001-10-30 2010-02-16 Colorado State University Research Foundation Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest
US7160492B2 (en) * 2001-12-12 2007-01-09 Depuy Products, Inc. Orthopaedic device for implantation in the body of an animal and method for making the same
AU2002334649B2 (en) * 2002-01-04 2007-12-06 Cambridge Polymer Group Inc. A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
US7186364B2 (en) * 2002-01-28 2007-03-06 Depuy Products, Inc. Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same
US7238744B2 (en) * 2002-04-12 2007-07-03 Daramic, Inc. Ultrahigh molecular weight polyethylene articles and method of manufacture
US20050019366A1 (en) * 2002-12-31 2005-01-27 Zeldis Jerome B. Drug-coated stents and methods of use therefor
AU2004206826B8 (en) * 2003-01-16 2009-03-26 Cambridge Polymer Group, Inc. Methods for making oxidation resistant polymeric material
US7938861B2 (en) * 2003-04-15 2011-05-10 Depuy Products, Inc. Implantable orthopaedic device and method for making the same
US7214764B2 (en) * 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20040265165A1 (en) * 2003-06-30 2004-12-30 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20040262809A1 (en) * 2003-06-30 2004-12-30 Smith Todd S. Crosslinked polymeric composite for orthopaedic implants
US20050065307A1 (en) * 2003-09-19 2005-03-24 Depuy Products, Inc. Medical implant or medical implant part comprising porous UHMWPE and process for producing the same
US7205051B2 (en) * 2003-09-30 2007-04-17 Depuy Products, Inc. Medical implant or medical implant part
US20060062825A1 (en) * 2004-04-19 2006-03-23 Maria Maccecchini Method of implanting a sterile, active agent-coated material and composition made according to same
US7384430B2 (en) * 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
CA2583911A1 (en) * 2004-10-28 2006-05-11 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
US7335697B2 (en) * 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
US7879275B2 (en) * 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7896921B2 (en) * 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same

Also Published As

Publication number Publication date
US20070077268A1 (en) 2007-04-05
EP1779877B1 (de) 2010-12-15
DK1779877T3 (da) 2011-03-14
DE602006018845D1 (de) 2011-01-27
ES2356253T3 (es) 2011-04-06
EP1779877A1 (de) 2007-05-02

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