ATE491719T1 - Peptidinhibitoren gegen den eintritt von hiv in zellen - Google Patents

Peptidinhibitoren gegen den eintritt von hiv in zellen

Info

Publication number
ATE491719T1
ATE491719T1 AT01973355T AT01973355T ATE491719T1 AT E491719 T1 ATE491719 T1 AT E491719T1 AT 01973355 T AT01973355 T AT 01973355T AT 01973355 T AT01973355 T AT 01973355T AT E491719 T1 ATE491719 T1 AT E491719T1
Authority
AT
Austria
Prior art keywords
cells
hiv entry
against hiv
peptide inhibitors
inhibitors against
Prior art date
Application number
AT01973355T
Other languages
English (en)
Inventor
Debra Eckert
Tara Suntoke
Peter Kim
Original Assignee
Whitehead Biomedical Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/668,072 external-priority patent/US6747126B1/en
Application filed by Whitehead Biomedical Inst filed Critical Whitehead Biomedical Inst
Application granted granted Critical
Publication of ATE491719T1 publication Critical patent/ATE491719T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01973355T 2000-09-22 2001-09-21 Peptidinhibitoren gegen den eintritt von hiv in zellen ATE491719T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/668,072 US6747126B1 (en) 1998-07-30 2000-09-22 Peptide inhibitors of HIV entry
PCT/US2001/029637 WO2002024735A2 (en) 2000-09-22 2001-09-21 Peptide inhibitors of hiv entry

Publications (1)

Publication Number Publication Date
ATE491719T1 true ATE491719T1 (de) 2011-01-15

Family

ID=24680888

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01973355T ATE491719T1 (de) 2000-09-22 2001-09-21 Peptidinhibitoren gegen den eintritt von hiv in zellen

Country Status (7)

Country Link
EP (1) EP1353942B1 (de)
JP (1) JP5180422B2 (de)
AT (1) ATE491719T1 (de)
AU (3) AU2001292944B2 (de)
CA (1) CA2423004C (de)
DE (1) DE60143668D1 (de)
WO (1) WO2002024735A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7960504B2 (en) 1998-07-30 2011-06-14 Whitehead Institute For Biomedical Research Inhibitors of HIV membrane fusion
US6747126B1 (en) 1998-07-30 2004-06-08 Whitehead Institute For Biomedical Research Peptide inhibitors of HIV entry
DE60037450T2 (de) 1999-12-16 2008-12-04 Whitehead Institute For Biomedical Research, Cambridge Fünf-helix protein
EP1500662A3 (de) * 2003-05-19 2005-09-21 Cornell Research Foundation, Inc. Stabilisierende Peptide und Ihre Verwendung zur Herstellung von stabilisierten HIV-Inhibitoren
WO2004106364A1 (en) * 2003-08-05 2004-12-09 Cornell Research Foundation, Inc. Stabilizing peptides and their use in the preparation of stabilized hiv inhibitors
PL1692265T3 (pl) * 2003-11-04 2011-12-30 The Administrators Of The Tulane Educational Fund Sposób zapobiegania fuzji wirus:komórka przez hamowanie działania regionu inicjowania fuzji w wirusach RNA zawierających fuzogenne błonowe białka otoczki klasy I
EP1755667B1 (de) * 2004-06-01 2013-07-17 Merck Sharp & Dohme Corp. Stabiles peptidmimetikum des hiv gp41-fusionszwischenproduktes
EP1868652A2 (de) * 2005-04-05 2007-12-26 Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. Verfahren zur abschirmung von funktionalen stellen oder epitopen auf proteinen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010099605A (ko) * 1998-07-30 2001-11-09 존 프랫 Hiv 막융합 억제제
JP2003529319A (ja) * 1999-01-08 2003-10-07 キャロル ディ. ウエイス, HIV−1gp41を標的化する広範に中和する抗体を誘発する方法
RU2143843C1 (ru) * 1999-04-28 2000-01-10 Обабков Анатолий Иванович Способ экспресс-диагностики физиологического состояния биологического объекта и устройство для его осуществления

Also Published As

Publication number Publication date
WO2002024735A3 (en) 2003-08-14
EP1353942B1 (de) 2010-12-15
CA2423004C (en) 2012-09-11
JP5180422B2 (ja) 2013-04-10
CA2423004A1 (en) 2002-03-28
WO2002024735A2 (en) 2002-03-28
AU2005225063B2 (en) 2009-06-25
DE60143668D1 (de) 2011-01-27
JP2004509901A (ja) 2004-04-02
AU9294401A (en) 2002-04-02
EP1353942A2 (de) 2003-10-22
AU2005225063A1 (en) 2005-11-10
AU2001292944B2 (en) 2005-07-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties