ATE491719T1 - Peptidinhibitoren gegen den eintritt von hiv in zellen - Google Patents

Peptidinhibitoren gegen den eintritt von hiv in zellen

Info

Publication number
ATE491719T1
ATE491719T1 AT01973355T AT01973355T ATE491719T1 AT E491719 T1 ATE491719 T1 AT E491719T1 AT 01973355 T AT01973355 T AT 01973355T AT 01973355 T AT01973355 T AT 01973355T AT E491719 T1 ATE491719 T1 AT E491719T1
Authority
AT
Austria
Prior art keywords
cells
hiv entry
against hiv
peptide inhibitors
inhibitors against
Prior art date
Application number
AT01973355T
Other languages
English (en)
Inventor
Debra Eckert
Tara Suntoke
Peter Kim
Original Assignee
Whitehead Biomedical Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/668,072 external-priority patent/US6747126B1/en
Application filed by Whitehead Biomedical Inst filed Critical Whitehead Biomedical Inst
Application granted granted Critical
Publication of ATE491719T1 publication Critical patent/ATE491719T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT01973355T 2000-09-22 2001-09-21 Peptidinhibitoren gegen den eintritt von hiv in zellen ATE491719T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/668,072 US6747126B1 (en) 1998-07-30 2000-09-22 Peptide inhibitors of HIV entry
PCT/US2001/029637 WO2002024735A2 (en) 2000-09-22 2001-09-21 Peptide inhibitors of hiv entry

Publications (1)

Publication Number Publication Date
ATE491719T1 true ATE491719T1 (de) 2011-01-15

Family

ID=24680888

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01973355T ATE491719T1 (de) 2000-09-22 2001-09-21 Peptidinhibitoren gegen den eintritt von hiv in zellen

Country Status (7)

Country Link
EP (1) EP1353942B1 (de)
JP (1) JP5180422B2 (de)
AT (1) ATE491719T1 (de)
AU (3) AU9294401A (de)
CA (1) CA2423004C (de)
DE (1) DE60143668D1 (de)
WO (1) WO2002024735A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747126B1 (en) 1998-07-30 2004-06-08 Whitehead Institute For Biomedical Research Peptide inhibitors of HIV entry
US7960504B2 (en) 1998-07-30 2011-06-14 Whitehead Institute For Biomedical Research Inhibitors of HIV membrane fusion
CA2395291C (en) 1999-12-16 2012-09-11 Whitehead Institute For Biomedical Research Five-helix protein
EP1500662A3 (de) * 2003-05-19 2005-09-21 Cornell Research Foundation, Inc. Stabilisierende Peptide und Ihre Verwendung zur Herstellung von stabilisierten HIV-Inhibitoren
WO2004106364A1 (en) * 2003-08-05 2004-12-09 Cornell Research Foundation, Inc. Stabilizing peptides and their use in the preparation of stabilized hiv inhibitors
ES2372633T3 (es) * 2003-11-04 2012-01-25 The Administrators Of The Tulane Educational Fund Procedimiento de evitar condensación de virus: células inhibiendo la función de la región de iniciación de condensación en los virus arn que tienen proteínas de envoltura fusogénicas de membrana de clase i.
JP5069558B2 (ja) * 2004-06-01 2012-11-07 メルク・シャープ・エンド・ドーム・コーポレイション HIVgp41融合中間物質の安定したペプチド模倣薬
EP1868652A2 (de) * 2005-04-05 2007-12-26 Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. Verfahren zur abschirmung von funktionalen stellen oder epitopen auf proteinen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1100818B1 (de) * 1998-07-30 2013-01-02 Whitehead Institute For Biomedical Research Inhibitoren der membranfusion von hiv
CA2359892A1 (en) * 1999-01-08 2000-07-13 Panacos Pharmaceuticals, Inc. Methods of eliciting broadly neutralizing antibodies targeting hiv-1 gp41
RU2143843C1 (ru) * 1999-04-28 2000-01-10 Обабков Анатолий Иванович Способ экспресс-диагностики физиологического состояния биологического объекта и устройство для его осуществления

Also Published As

Publication number Publication date
WO2002024735A2 (en) 2002-03-28
JP2004509901A (ja) 2004-04-02
EP1353942B1 (de) 2010-12-15
AU2005225063B2 (en) 2009-06-25
AU2001292944B2 (en) 2005-07-21
CA2423004C (en) 2012-09-11
AU2005225063A1 (en) 2005-11-10
EP1353942A2 (de) 2003-10-22
DE60143668D1 (de) 2011-01-27
WO2002024735A3 (en) 2003-08-14
JP5180422B2 (ja) 2013-04-10
AU9294401A (en) 2002-04-02
CA2423004A1 (en) 2002-03-28

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