ATE492286T1 - Poly-epitop peptid abgeleitet aus der thymidylat- synthase mit immunologischer und anti-tumor aktivität - Google Patents

Poly-epitop peptid abgeleitet aus der thymidylat- synthase mit immunologischer und anti-tumor aktivität

Info

Publication number
ATE492286T1
ATE492286T1 AT06711432T AT06711432T ATE492286T1 AT E492286 T1 ATE492286 T1 AT E492286T1 AT 06711432 T AT06711432 T AT 06711432T AT 06711432 T AT06711432 T AT 06711432T AT E492286 T1 ATE492286 T1 AT E492286T1
Authority
AT
Austria
Prior art keywords
immunological
poly
tumor activity
peptide derived
epitope peptide
Prior art date
Application number
AT06711432T
Other languages
English (en)
Inventor
Pierpaolo Correale
Maria Cusi
Guido Francini
Giorgio Giorgi
Original Assignee
Univ Siena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Siena filed Critical Univ Siena
Application granted granted Critical
Publication of ATE492286T1 publication Critical patent/ATE492286T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06711432T 2005-02-16 2006-02-15 Poly-epitop peptid abgeleitet aus der thymidylat- synthase mit immunologischer und anti-tumor aktivität ATE492286T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000064A ITRM20050064A1 (it) 2005-02-16 2005-02-16 Peptide poliepitopico derivato dalla timidilato sintetasi avente attivita' immunologica e antitumorale e composizioni farmaceutiche relative.
PCT/IT2006/000078 WO2006087756A2 (en) 2005-02-16 2006-02-15 Poly-epitope peptide derived from thymidylate synthase having immunological and anti-tumour activity

Publications (1)

Publication Number Publication Date
ATE492286T1 true ATE492286T1 (de) 2011-01-15

Family

ID=36604211

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06711432T ATE492286T1 (de) 2005-02-16 2006-02-15 Poly-epitop peptid abgeleitet aus der thymidylat- synthase mit immunologischer und anti-tumor aktivität

Country Status (15)

Country Link
US (1) US8344100B2 (de)
EP (1) EP1848456B1 (de)
JP (1) JP4943348B2 (de)
CN (1) CN101137392A (de)
AT (1) ATE492286T1 (de)
AU (1) AU2006215260B2 (de)
CA (1) CA2598292C (de)
DE (1) DE602006019057D1 (de)
ES (1) ES2357548T3 (de)
IL (1) IL185101A0 (de)
IT (1) ITRM20050064A1 (de)
MX (1) MX2007009896A (de)
NZ (1) NZ560511A (de)
RU (1) RU2007134338A (de)
WO (1) WO2006087756A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20050064A1 (it) 2005-02-16 2006-08-17 Univ Siena Peptide poliepitopico derivato dalla timidilato sintetasi avente attivita' immunologica e antitumorale e composizioni farmaceutiche relative.
NZ582823A (en) * 2007-07-27 2012-04-27 Immatics Biotechnologies Gmbh Composition of tumour-associated peptides and related anti-cancer vaccine
US8501242B2 (en) 2009-05-29 2013-08-06 University Of Florida Research Foundation Methods and compositions for treating neoplasia
CN101948508B (zh) * 2010-09-09 2012-07-04 郑州大学 Piwil2抗肿瘤ctl表位肽及其应用
RU2507265C2 (ru) * 2012-05-12 2014-02-20 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт клинической иммунологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИКИ" СО РАМН) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pCI-UB-POLYEPI, СОДЕРЖАЩАЯ ЭПИТОПЫ ОПУХОЛЬ-АССОЦИИРОВАННЫХ АНТИГЕНОВ ДЛЯ КОЛОРЕКТАЛЬНОГО РАКА, И СПОСОБ ЕЕ ПРИМЕНЕНИЯ ДЛЯ СТИМУЛЯЦИИ СПЕЦИФИЧЕСКОГО ПРОТИВООПУХОЛЕВОГО ИММУННОГО ОТВЕТА ПРОТИВ КЛЕТОК КОЛОРЕКТАЛЬНОГО РАКА
CN113827740A (zh) * 2021-09-17 2021-12-24 青岛农业大学 一种水溶性复合疫苗佐剂的筛选方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593456B1 (en) * 1996-11-06 2003-07-15 The Regents Of The University Of California Tumor necrosis factor receptor releasing enzyme
US7462354B2 (en) 1999-12-28 2008-12-09 Pharmexa Inc. Method and system for optimizing minigenes and peptides encoded thereby
US7378495B2 (en) 2002-10-21 2008-05-27 Pevion Biotech, Ltd. PTH-rP related peptide cancer therapeutics
ITRM20050064A1 (it) 2005-02-16 2006-08-17 Univ Siena Peptide poliepitopico derivato dalla timidilato sintetasi avente attivita' immunologica e antitumorale e composizioni farmaceutiche relative.

Also Published As

Publication number Publication date
WO2006087756A2 (en) 2006-08-24
CN101137392A (zh) 2008-03-05
DE602006019057D1 (de) 2011-02-03
RU2007134338A (ru) 2009-03-27
EP1848456B1 (de) 2010-12-22
JP2008529522A (ja) 2008-08-07
CA2598292C (en) 2017-04-04
IL185101A0 (en) 2007-12-03
NZ560511A (en) 2010-07-30
US20080305091A1 (en) 2008-12-11
AU2006215260A1 (en) 2006-08-24
ES2357548T3 (es) 2011-04-27
US8344100B2 (en) 2013-01-01
ITRM20050064A1 (it) 2006-08-17
CA2598292A1 (en) 2006-08-24
MX2007009896A (es) 2008-02-12
EP1848456A2 (de) 2007-10-31
WO2006087756A3 (en) 2006-11-02
JP4943348B2 (ja) 2012-05-30
AU2006215260B2 (en) 2011-04-28

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Legal Events

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