ATE492804T1 - Verfahren und vorrichtung zur chromatographischen reinigung - Google Patents

Verfahren und vorrichtung zur chromatographischen reinigung

Info

Publication number
ATE492804T1
ATE492804T1 AT06721934T AT06721934T ATE492804T1 AT E492804 T1 ATE492804 T1 AT E492804T1 AT 06721934 T AT06721934 T AT 06721934T AT 06721934 T AT06721934 T AT 06721934T AT E492804 T1 ATE492804 T1 AT E492804T1
Authority
AT
Austria
Prior art keywords
section
outlet
inlet
intermediate product
impurities
Prior art date
Application number
AT06721934T
Other languages
English (en)
Inventor
Lars Aumann
Massimo Morbidelli
Original Assignee
Eidgenoess Tech Hochschule
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eidgenoess Tech Hochschule filed Critical Eidgenoess Tech Hochschule
Application granted granted Critical
Publication of ATE492804T1 publication Critical patent/ATE492804T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/1828—Simulated moving beds characterised by process features
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
AT06721934T 2005-04-29 2006-04-27 Verfahren und vorrichtung zur chromatographischen reinigung ATE492804T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05405327 2005-04-29
EP05405421A EP1716900A1 (de) 2005-04-29 2005-07-01 Verfahren und Vorrichtung zur chromatographischen Reinigung
PCT/CH2006/000232 WO2006116886A1 (en) 2005-04-29 2006-04-27 Method and device for chromatographic purification

Publications (1)

Publication Number Publication Date
ATE492804T1 true ATE492804T1 (de) 2011-01-15

Family

ID=36602964

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06721934T ATE492804T1 (de) 2005-04-29 2006-04-27 Verfahren und vorrichtung zur chromatographischen reinigung

Country Status (8)

Country Link
US (2) US7837881B2 (de)
EP (2) EP1716900A1 (de)
JP (1) JP5133872B2 (de)
CN (1) CN101166564B (de)
AT (1) ATE492804T1 (de)
DE (1) DE602006019082D1 (de)
DK (1) DK1877769T3 (de)
WO (1) WO2006116886A1 (de)

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FR2889665B1 (fr) 2005-08-12 2007-11-09 Pic Solution Soc Par Actions S Procede et installation pour la regulation du taux de modificateur dans une chromatographie ou extraction supercritique avec recyclage
JP5140721B2 (ja) 2007-04-17 2013-02-13 イクスエンド、ホールディング、ベスローテン、フェンノートシャップ 連続メンブレン吸着方法および装置
WO2008153472A1 (en) * 2007-06-15 2008-12-18 Ge Healthcare Bio-Sciences Ab Chromatography method
FR2929533B1 (fr) * 2008-04-03 2010-04-30 Novasep Procede de separation multicolonnes a gradient.
CN102271776B (zh) * 2009-01-06 2014-06-11 克罗麦肯公司 多级分纯化方法和用于所述方法的设备
PL3702775T3 (pl) 2009-06-26 2026-03-30 Cytiva Sweden Ab Sposób oznaczania zdolności wiązania w układzie chromatograficznym
US9527010B2 (en) * 2009-09-25 2016-12-27 Ge Healthcare Bio-Sciences Corp. Separation system and method
JP2013544524A (ja) * 2010-12-06 2013-12-19 ターポン バイオシステムズ，インコーポレイテッド 生物学的生成物の連続プロセス法
EP2500073A1 (de) 2011-03-17 2012-09-19 ChromaCon AG Verfahren zur Identifizierung und Reinigung von mehrfach spezifischen Polypeptiden
WO2013083482A1 (en) 2011-12-05 2013-06-13 Chromacon Ag Chromatographic method for the separation of fatty acid mixtures
CN102728102B (zh) * 2012-07-18 2014-06-18 成都欧林生物科技股份有限公司 一种大型凝胶层析柱纯化有机大分子物质的工艺
DK2772289T3 (en) 2013-03-01 2015-08-10 Chromacon Ag Chromatographic method for the enrichment and isolation
US10948483B2 (en) 2013-04-08 2021-03-16 Chromacon Ag Method for control, monitoring and/or optimization of a chromatographic process
US10099156B2 (en) * 2013-04-08 2018-10-16 Chromacon Ag Chromatographic purification method
US10226719B2 (en) 2014-09-30 2019-03-12 Exxonmobil Chemical Patents Inc. Adsorptive separation of multi-component fluid mixtures
WO2016127330A1 (zh) * 2015-02-11 2016-08-18 王峰 一种二维液相色谱仪
EP3037513A1 (de) * 2015-05-13 2016-06-29 Bayer Technology Services GmbH Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen
GB201710130D0 (en) * 2017-06-26 2017-08-09 Ge Healthcare Bioprocess R & D Ab A Method of seperation
PL3512616T5 (pl) 2017-11-16 2022-12-19 Chromacon Ag Sposób monitorowania, oceny i sterowania cyklicznym procesem oczyszczania techniką chromatograficzną
WO2020076818A1 (en) * 2018-10-09 2020-04-16 C Technologies, Inc. Mass control system for chromatography
DK3839497T3 (da) 2018-11-16 2023-05-22 Organo Corp Kromatografisk separationsfremgangsmåde ved hjælp af simuleret moving-bed-teknik, og kromatografisk separationssystem ved hjælp af simuleret moving-bed-teknik
GB201902743D0 (en) * 2019-02-28 2019-04-17 Ge Healthcare Bio Sciences Ab Improvements in and relating to optimizing the operation of a chromatography system
EP4110492B1 (de) * 2020-02-28 2025-04-23 Waters Technologies Corporation Steuerbare probeneinführung
KR102949589B1 (ko) * 2020-09-15 2026-04-06 주식회사 엘지화학 유기 발광 소자용 유기물의 정제 방법 및 정제 장치
WO2022201002A1 (en) * 2021-03-25 2022-09-29 Waters Technologies Corporation Automated semi-preparative gradient recycling liquid chromatography
US12292422B2 (en) * 2021-09-18 2025-05-06 Shimadzu Corporation Liquid chromatograph and flow path cleaning method in liquid chromatograph
IL310482A (en) * 2021-09-28 2024-03-01 Chromacon Ag Purification method and uses thereof
WO2023165947A1 (en) 2022-03-03 2023-09-07 Chromacon Ag Chromatographic purification method and uses thereof
JPWO2024262581A1 (de) * 2023-06-22 2024-12-26

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US5560827A (en) * 1995-02-02 1996-10-01 Tennessee Valley Authority Exclusion chromatographic separation of ionic from nonionic solutes
JP3554808B2 (ja) * 1996-12-11 2004-08-18 株式会社 日立インダストリイズ 擬似移動床方式のクロマト分離法
JP3453516B2 (ja) * 1998-05-29 2003-10-06 オルガノ株式会社 クロマト分離方法
JP4627841B2 (ja) * 2000-06-08 2011-02-09 国立大学法人 香川大学 プシコースの分離方法
US6740243B2 (en) * 2000-11-15 2004-05-25 Purdue Research Foundation Systems and processes for performing separations using a simulated moving bed apparatus
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JP2004077329A (ja) * 2002-08-20 2004-03-11 Japan Organo Co Ltd クロマト分離装置
JP2006507249A (ja) * 2002-09-13 2006-03-02 バイオジェン アイデック インコーポレイテッド 疑似移動床式クロマトグラフィーによる、ポリペプチドを精製する方法
FR2846252B1 (fr) 2002-10-29 2005-07-01 Novasep Procede et dispositif de chromatographie integrant une etape de concentration

Also Published As

Publication number Publication date
CN101166564A (zh) 2008-04-23
US20090050567A1 (en) 2009-02-26
US20110042310A1 (en) 2011-02-24
EP1877769B1 (de) 2010-12-22
WO2006116886A1 (en) 2006-11-09
JP2008539395A (ja) 2008-11-13
EP1877769A1 (de) 2008-01-16
JP5133872B2 (ja) 2013-01-30
US7837881B2 (en) 2010-11-23
DK1877769T3 (da) 2011-03-28
US8496836B2 (en) 2013-07-30
DE602006019082D1 (de) 2011-02-03
CN101166564B (zh) 2010-12-08
EP1716900A1 (de) 2006-11-02

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