ATE493652T1 - Quantitative assays für pdgfr-beta- in körperflüssigkeiten - Google Patents

Quantitative assays für pdgfr-beta- in körperflüssigkeiten

Info

Publication number
ATE493652T1
ATE493652T1 AT06801170T AT06801170T ATE493652T1 AT E493652 T1 ATE493652 T1 AT E493652T1 AT 06801170 T AT06801170 T AT 06801170T AT 06801170 T AT06801170 T AT 06801170T AT E493652 T1 ATE493652 T1 AT E493652T1
Authority
AT
Austria
Prior art keywords
beta
diseases
body fluid
patient
monitor
Prior art date
Application number
AT06801170T
Other languages
English (en)
Inventor
Peter Hamer
Walter Carney
Leticia Morris
James Elting
Original Assignee
Siemens Healthcare Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics filed Critical Siemens Healthcare Diagnostics
Application granted granted Critical
Publication of ATE493652T1 publication Critical patent/ATE493652T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57545—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/49—Platelet-derived growth factor [PDGF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Steroid Compounds (AREA)
AT06801170T 2005-08-11 2006-08-10 Quantitative assays für pdgfr-beta- in körperflüssigkeiten ATE493652T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70780605P 2005-08-11 2005-08-11
PCT/US2006/031245 WO2007021860A2 (en) 2005-08-11 2006-08-10 QUANTITATIVE ASSAYS FOR PDGFR-β IN BODY FLUIDS

Publications (1)

Publication Number Publication Date
ATE493652T1 true ATE493652T1 (de) 2011-01-15

Family

ID=37758168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06801170T ATE493652T1 (de) 2005-08-11 2006-08-10 Quantitative assays für pdgfr-beta- in körperflüssigkeiten

Country Status (5)

Country Link
US (1) US20070037224A1 (de)
EP (1) EP1913391B1 (de)
AT (1) ATE493652T1 (de)
DE (1) DE602006019262D1 (de)
WO (1) WO2007021860A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124630B2 (en) * 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
EP2298311B1 (de) * 1999-01-13 2012-05-09 Bayer HealthCare LLC Omega-carboxyarylsubstituierte-Diphenyl-Harnstoffe als p38-Kinasehemmer
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
DK1478358T3 (da) * 2002-02-11 2013-10-07 Bayer Healthcare Llc Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese
US7874293B2 (en) * 2003-02-21 2011-01-25 Resmed Limited Nasal assembly
UY28213A1 (es) * 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
US8068990B2 (en) * 2003-03-25 2011-11-29 Hologic, Inc. Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
US7191068B2 (en) * 2003-03-25 2007-03-13 Proteogenix, Inc. Proteomic analysis of biological fluids
EP1636585B2 (de) * 2003-05-20 2012-06-13 Bayer HealthCare LLC Diaryl-harnstoffe mit kinasehemmender wirkung
CN101506351A (zh) * 2005-10-21 2009-08-12 拜尔健康护理有限责任公司 用于癌症预测和预后及监测癌症治疗的方法
JP5967861B2 (ja) * 2007-04-03 2016-08-10 オキシレイン ユーケー リミテッド 分子のグリコシル化
US20110124965A1 (en) * 2008-05-08 2011-05-26 Park Jason Y Chemiluminescence enhanced detection
US20100004306A1 (en) * 2008-06-18 2010-01-07 Abbott Laboratories PIGF-1 Assay and kits and components thereof
US8741287B2 (en) * 2008-06-18 2014-06-03 Abbott Laboratories PlGF-1 assay and kits and components thereof
CA2728449A1 (en) * 2008-06-18 2009-12-23 Abbott Laboratories P/gf-1 companion diagnostic methods and products
EP2324111B1 (de) * 2008-09-10 2013-07-03 Life & Brain GmbH Peripherbereichs-tumorzellen sowie verfahren zu ihrer herstellung und verwendung
CN107014996A (zh) * 2009-03-19 2017-08-04 昂热大学 用于评估肝纤维化进展的非侵入方法
CN102445543B (zh) * 2010-10-08 2014-03-12 中国医学科学院肿瘤研究所 辅助诊断肺癌淋巴结转移的试剂
GB201204014D0 (en) * 2012-03-07 2012-04-18 Univ Leeds Diagnostic marker compounds and their use
JP6417602B2 (ja) 2013-03-15 2018-11-07 エーザイ インコーポレイテッド 大腸直腸癌の予後を判定する方法
CN105074467B (zh) 2013-04-25 2018-06-15 株式会社Cbs生物科学 提高分子靶向治疗肝细胞癌的敏感性的分析方法
EP3491388B1 (de) 2016-08-01 2021-09-01 Centre Hospitalier Universitaire d'Angers Multi-zielgerichteten fibrosetests
WO2020099487A1 (en) * 2018-11-14 2020-05-22 Vrije Universiteit Brussel Soluble pdgfrbeta as a biomarker for fibrosis
KR102363980B1 (ko) * 2020-04-13 2022-02-15 전남대학교산학협력단 전이성 뇌종양의 진단 또는 예후 분석용 바이오마커 및 이를 이용한 진단방법
US20230392209A1 (en) * 2020-10-21 2023-12-07 Prelude Corporation Methods for treating a subject with local invasive breast cancer based on pdgfrb levels
CN116997566A (zh) * 2021-03-19 2023-11-03 伊莱利利公司 用PDGFRα抑制剂治疗癌症的方法
CN118440214B (zh) * 2024-04-02 2025-01-28 山东大学 一种靶向PDGFRβ的嵌合抗原受体、CAR-T细胞及应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4745181A (en) 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US6110737A (en) * 1988-02-02 2000-08-29 The Regents Of The University Of California Human platelet-derived growth factor receptor, type A
US6642022B1 (en) * 1988-02-02 2003-11-04 The Regents Of The University Of California Platelet-derived growth factor receptors
DK0456766T3 (da) * 1989-02-09 1999-11-08 Us Health Gen for receptor for type alfa-blodplade-afledt vækstfaktor
US5468468A (en) * 1989-02-09 1995-11-21 The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services Method for making a monoclonal antibody, monoclonal antibodies to α PD
US6228600B1 (en) * 1992-07-20 2001-05-08 The United States Of America As Represented By The Department Of Health And Human Services Immunoassays for the alpha platelet-derived growth factor receptor
EP0474744B1 (de) * 1989-05-22 1994-08-03 Zymogenetics, Inc. Pdgf-alpha-rezeptor
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
DE69233528T2 (de) 1991-11-25 2006-03-16 Enzon, Inc. Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
US5817310A (en) * 1991-12-02 1998-10-06 Cor Therapeutics, Inc. Inhibitory immunoglobulin polypeptides to human PDGF beta receptor
US5395752A (en) 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
US6264949B1 (en) * 1998-09-29 2001-07-24 Mount Sinai School Of Medicine Of New York University Noninvasive agents for diagnosis and prognosis of the progression of fibrosis
ATE441107T1 (de) * 2002-03-01 2009-09-15 Siemens Healthcare Diagnostics Assays zur überwachung von krebspatienten auf grundlage der spiegel des analyten für die extrazelluläre domäne (ecd) des epidermalen wachstumsfaktor-rezeptors (egfr), allein oder in kombination mit anderen analyten, in proben von kírperflüssigkeiten
EP1636585B2 (de) * 2003-05-20 2012-06-13 Bayer HealthCare LLC Diaryl-harnstoffe mit kinasehemmender wirkung
WO2005015236A2 (en) * 2003-07-18 2005-02-17 Roche Diagnostics Gmbh A method for predicting the progression of adenocarcinoma

Also Published As

Publication number Publication date
US20070037224A1 (en) 2007-02-15
WO2007021860B1 (en) 2008-02-28
EP1913391A2 (de) 2008-04-23
WO2007021860A2 (en) 2007-02-22
EP1913391B1 (de) 2010-12-29
DE602006019262D1 (de) 2011-02-10
WO2007021860A3 (en) 2007-10-04
EP1913391A4 (de) 2009-02-18

Similar Documents

Publication Publication Date Title
DE602006019262D1 (de) QUANTITATIVE ASSAYS FÜR PDGFR-beta- IN KÖRPERFLÜSSIGKEITEN
Pin et al. The role of proteomics in prostate cancer research: biomarker discovery and validation
DE602006018578D1 (de) Diagnose- und prognoseverfahren von blasenkrebs.
WO2009019230A3 (en) Use of procalcitonin (pct) in risk stratification and prognosis of patients with a primary, non-infectious disease
RU2017126701A (ru) Способ детекции нуклеосом, содержащих нуклеотиды
ATE554386T1 (de) Verbesserte immunoassayverfahren
WO2004058044A3 (en) Diagnostic method for diseases by screening for hepcidin in human or animal tissues, blood or body fluids and therapeutic uses therefor
JP2017215338A5 (de)
DE602006011896D1 (de) Diagnoseverfahren für erkrankungen im zusammenhang mit hirnschäden
Leung et al. Ovarian cancer biomarkers: current state and future implications from high-throughput technologies
WO2008069975A3 (en) Methods of using f-spondin as a biomarker for cartilage degenerative conditions
BRPI0412725A (pt) marcadores para detecção de cáncer gástrico
NZ609493A (en) Diagnosis and treatments relating to th2 inhibition
EP3708682A3 (de) Verwendung von mikrovesikeln bei der diagnose und prognose von medizinischen krankheiten und leiden
RU2018101257A (ru) Способ детекции нуклеосом, содержащих гистоновые варианты
WO2004046729A3 (en) Bodily fluid markers of tissue hypoxia
TR201900083T4 (tr) İnsan idrarının toplanmasına ve analizine yönelik aparat.
WO2007146668A3 (en) Use of imp3 as a prognostic marker for cancer
CN101449163A (zh) S100a12蛋白作为结肠直肠癌标记的用途
WO2007080597A3 (en) Polynucleotide and polypeptide sequences and methods for diagnosis
Dalirsani et al. Comparison of matrix metalloproteinases 2 and 9 levels in saliva and serum of patients with head and neck squamous cell carcinoma and healthy subjects
WO2025031524A3 (zh) 用于预测甲状腺癌转移的标志物组合及其应用
ATE476652T1 (de) Quantitative assays für ras p21 in körperflüssigkeiten
BR112013030646A2 (pt) uso diagnóstico de pró-somatostatina
Nagasen et al. Molecular warriors: Proteases as sentinels in the war against cancer diagnosis and prognosis

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties