ATE493986T1 - Diarylharnstoffe zur behandlung von pulmonaler hypertonie - Google Patents

Diarylharnstoffe zur behandlung von pulmonaler hypertonie

Info

Publication number
ATE493986T1
ATE493986T1 AT06828882T AT06828882T ATE493986T1 AT E493986 T1 ATE493986 T1 AT E493986T1 AT 06828882 T AT06828882 T AT 06828882T AT 06828882 T AT06828882 T AT 06828882T AT E493986 T1 ATE493986 T1 AT E493986T1
Authority
AT
Austria
Prior art keywords
diarylureas
treatment
pulmonary hypertension
hypertension
pulmonary
Prior art date
Application number
AT06828882T
Other languages
English (en)
Inventor
Peter Sandner
Hanna Tinel
Joachim Huetter
Bernd Riedl
Martina Klein
Ralph Schermuly
Friedrich Grimminger
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of ATE493986T1 publication Critical patent/ATE493986T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06828882T 2005-11-10 2006-10-30 Diarylharnstoffe zur behandlung von pulmonaler hypertonie ATE493986T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05024508 2005-11-10
EP05027449 2005-12-15
EP06007775 2006-04-13
PCT/EP2006/010405 WO2007054215A1 (en) 2005-11-10 2006-10-30 Diaryl ureas for treating pulmonary hypertension

Publications (1)

Publication Number Publication Date
ATE493986T1 true ATE493986T1 (de) 2011-01-15

Family

ID=37651281

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06828882T ATE493986T1 (de) 2005-11-10 2006-10-30 Diarylharnstoffe zur behandlung von pulmonaler hypertonie

Country Status (23)

Country Link
US (1) US20090176791A1 (de)
EP (1) EP1948176B1 (de)
JP (1) JP5075832B2 (de)
KR (1) KR20080066030A (de)
AR (1) AR057848A1 (de)
AT (1) ATE493986T1 (de)
AU (1) AU2006312713A1 (de)
BR (1) BRPI0618524A2 (de)
CA (1) CA2628847A1 (de)
CU (1) CU23815A3 (de)
DE (1) DE602006019468D1 (de)
DK (1) DK1948176T3 (de)
EC (1) ECSP088429A (de)
IL (1) IL191010A0 (de)
MY (1) MY144860A (de)
NO (1) NO20082497L (de)
NZ (1) NZ568031A (de)
PL (1) PL1948176T3 (de)
PT (1) PT1948176E (de)
SV (1) SV2009002899A (de)
TW (1) TW200735869A (de)
UY (1) UY29902A1 (de)
WO (1) WO2007054215A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
ATE538794T1 (de) 1999-01-13 2012-01-15 Bayer Healthcare Llc Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
US7838541B2 (en) 2002-02-11 2010-11-23 Bayer Healthcare, Llc Aryl ureas with angiogenesis inhibiting activity
UY28213A1 (es) 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
WO2004113274A2 (en) * 2003-05-20 2004-12-29 Bayer Pharmaceuticals Corporation Diaryl ureas with kinase inhibiting activity
RS52625B (sr) 2003-07-23 2013-06-28 Bayer Healthcare Llc Fluoro supstituisana omega-karboksiaril difenil urea za lečenje i prevenciju bolesti i stanja bolesti
KR101335932B1 (ko) 2005-03-07 2013-12-04 바이엘 헬스케어 엘엘씨 암의 치료를 위한 오메가-카르복시아릴 치환된 디페닐우레아를 포함하는 제약 조성물
US20090197922A1 (en) * 2006-01-24 2009-08-06 The University Of Chicago Compositions and methods for treating pulmonary hypertension
AR062927A1 (es) * 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
EP2129376B1 (de) 2007-01-19 2013-07-24 Bayer HealthCare LLC Behandlung von Tumoren mit erworbener Resistenz gegen KIT-Hemmer
EP2296641A1 (de) * 2008-06-25 2011-03-23 Bayer Schering Pharma Aktiengesellschaft Diarylharnstoff zur behandlung von herzinsuffizienz
EA201300420A1 (ru) 2010-10-01 2013-09-30 Байер Интеллектчуал Проперти Гмбх Комбинации, которые содержат замещенный n-(2-ариламино) арилсульфонамид
EP2723717A2 (de) 2011-06-24 2014-04-30 Amgen Inc. Trpm8-antagonisten und ihre verwendung bei behandlungen
AU2012272898A1 (en) 2011-06-24 2013-04-11 Amgen Inc. TRPM8 antagonists and their use in treatments
US8586527B2 (en) * 2011-10-20 2013-11-19 Jaipal Singh Cerivastatin to treat pulmonary disorders
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
EP3007689B1 (de) 2013-01-10 2018-03-07 Pulmokine, Inc. Nicht-selektive kinasehemmer
EP3054937B1 (de) 2013-10-11 2023-07-26 Pulmokine, Inc. Sprühtrocknungsformulierungen
WO2015089105A1 (en) 2013-12-09 2015-06-18 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
US11057446B2 (en) 2015-05-14 2021-07-06 Bright Data Ltd. System and method for streaming content from multiple servers
KR20230093341A (ko) 2016-10-27 2023-06-27 풀모킨 인코포레이티드 폐고혈압을 치료하기 위한 병용 요법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020065296A1 (en) * 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
US7928239B2 (en) * 1999-01-13 2011-04-19 Bayer Healthcare Llc Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
US7838541B2 (en) * 2002-02-11 2010-11-23 Bayer Healthcare, Llc Aryl ureas with angiogenesis inhibiting activity
WO2004113274A2 (en) * 2003-05-20 2004-12-29 Bayer Pharmaceuticals Corporation Diaryl ureas with kinase inhibiting activity

Also Published As

Publication number Publication date
WO2007054215A1 (en) 2007-05-18
PL1948176T3 (pl) 2011-05-31
EP1948176B1 (de) 2011-01-05
NZ568031A (en) 2011-06-30
AR057848A1 (es) 2007-12-19
US20090176791A1 (en) 2009-07-09
DK1948176T3 (da) 2011-04-18
CA2628847A1 (en) 2007-05-18
CU20080082A7 (es) 2011-07-11
NO20082497L (no) 2008-06-03
MY144860A (en) 2011-11-30
DE602006019468D1 (de) 2011-02-17
TW200735869A (en) 2007-10-01
AU2006312713A1 (en) 2007-05-18
IL191010A0 (en) 2009-08-03
KR20080066030A (ko) 2008-07-15
UY29902A1 (es) 2007-06-29
PT1948176E (pt) 2011-03-07
JP2009514909A (ja) 2009-04-09
EP1948176A1 (de) 2008-07-30
JP5075832B2 (ja) 2012-11-21
CU23815A3 (es) 2012-06-21
SV2009002899A (es) 2009-04-28
ECSP088429A (es) 2008-07-30
BRPI0618524A2 (pt) 2011-09-06

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