ATE494588T1 - Verfahren zur mikrorna-identifikation und ihrer anwendungen bei der forschung und menschlichen gesundheit - Google Patents

Verfahren zur mikrorna-identifikation und ihrer anwendungen bei der forschung und menschlichen gesundheit

Info

Publication number
ATE494588T1
ATE494588T1 AT06829959T AT06829959T ATE494588T1 AT E494588 T1 ATE494588 T1 AT E494588T1 AT 06829959 T AT06829959 T AT 06829959T AT 06829959 T AT06829959 T AT 06829959T AT E494588 T1 ATE494588 T1 AT E494588T1
Authority
AT
Austria
Prior art keywords
microrna
molecules
research
applications
human health
Prior art date
Application number
AT06829959T
Other languages
English (en)
Inventor
Olivier Delfour
Jerome Ciuti
Florent Denoual
David Vilanova
Bernard Michot
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Application granted granted Critical
Publication of ATE494588T1 publication Critical patent/ATE494588T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/50—Mutagenesis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/20—Sequence assembly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/10—Production naturally occurring
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06829959T 2005-11-08 2006-11-08 Verfahren zur mikrorna-identifikation und ihrer anwendungen bei der forschung und menschlichen gesundheit ATE494588T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05292359A EP1783645A1 (de) 2005-11-08 2005-11-08 Verfahren zur Identifizierung von MikroRNA Molekülen und deren Anwendungen in der Forschung und in der menschlichen Gesundheit
PCT/EP2006/068246 WO2007054520A2 (en) 2005-11-08 2006-11-08 Methods for the identification of microrna and their applications in research and human health

Publications (1)

Publication Number Publication Date
ATE494588T1 true ATE494588T1 (de) 2011-01-15

Family

ID=35840555

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06829959T ATE494588T1 (de) 2005-11-08 2006-11-08 Verfahren zur mikrorna-identifikation und ihrer anwendungen bei der forschung und menschlichen gesundheit

Country Status (7)

Country Link
US (2) US8116987B2 (de)
EP (3) EP1783645A1 (de)
AT (1) ATE494588T1 (de)
AU (1) AU2006311003B2 (de)
CA (1) CA2628941A1 (de)
DE (1) DE602006019475D1 (de)
WO (1) WO2007054520A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006039293A2 (en) * 2004-09-29 2006-04-13 University Of Virginia Patent Foundation Localized control of thermal properties on microdevices and applications thereof
WO2006044458A2 (en) 2004-10-13 2006-04-27 University Of Virginia Patent Foundation Electrostatic actuation for management of flow
CA2594277A1 (en) * 2004-12-22 2006-06-29 University Of Virginia Patent Foundation The use of microwaves for thermal and non-thermal applications in micro and nanoscale devices
WO2007030240A2 (en) * 2005-08-01 2007-03-15 University Of Virginia Patent Foundation Microdevices for chemical sensing and chemical actuation
AU2006283177B2 (en) * 2005-08-23 2011-11-17 University Of Virginia Patent Foundation Passive components for micro-fluidic flow profile shaping and related method thereof
WO2007041671A2 (en) * 2005-10-04 2007-04-12 University Of Virginia Patent Foundation Microchip-based acoustic trapping or capture of cells for forensic analysis and related method thereof
US8916375B2 (en) * 2005-10-12 2014-12-23 University Of Virginia Patent Foundation Integrated microfluidic analysis systems
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
US20100240057A1 (en) * 2007-11-08 2010-09-23 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of chronic myeloid leukemia and acute lymphoblastic leukemia
US20100240049A1 (en) 2009-01-16 2010-09-23 Cepheid Methods of Detecting Cervical Cancer
US9493832B2 (en) 2009-02-02 2016-11-15 Cepheid Methods of detecting sepsis
EP2401406A4 (de) * 2009-02-25 2012-09-19 Cepheid Verfahren für den nachweis von lungenkrebs
CN102482677B (zh) * 2009-03-16 2017-10-17 库尔纳公司 通过抑制nrf2的天然反义转录物治疗核因子(红细胞衍生2)‑样2(nrf2)相关疾病
CA2825522A1 (en) 2011-01-26 2012-08-02 Cepheid Methods of detecting lung cancer
AU2013323586B2 (en) 2012-09-28 2019-07-11 Cepheid Methods for DNA and RNA extraction from fixed paraffin-embedded tissue samples
WO2014093360A1 (en) 2012-12-10 2014-06-19 Landers James P Frequency-based filtering of mechanical actuation using fluidic device
US9458458B2 (en) 2013-11-11 2016-10-04 Emory University Manipulating microRNA for the management of neurological diseases or conditions and compositions related thereto
US10030263B1 (en) 2014-08-25 2018-07-24 University Of South Florida Multiplexed RNA qPCR assay
WO2017019293A1 (en) 2015-07-24 2017-02-02 Cepheid Compositions and methods for dna and rna extraction from tissue samples
JP7233149B2 (ja) * 2016-12-14 2023-03-06 ベニテック アイピー ホールディングス インコーポレーテッド 眼咽頭型筋ジストロフィー（ｏｐｍｄ）を治療するための試薬及びその使用
WO2018209024A1 (en) * 2017-05-10 2018-11-15 The Children's Hospital Of Philadelphia Methods of identifying mirnas and applications thereof
AU2018269050A1 (en) * 2017-05-19 2020-01-16 Encoded Therapeutics, Inc. High activity regulatory elements
EP3717505A4 (de) 2017-12-01 2021-12-01 Encoded Therapeutics, Inc. Gentechnisch veränderte dna-bindende proteine
PH12020551219A1 (en) * 2018-02-14 2021-04-19 Deep Genomics Incorporated Oligonucleotide therapy for wilson disease
WO2023196814A2 (en) * 2022-04-04 2023-10-12 Cornell University Reduction of iron levels by iron responsive protein sequestration with short rnas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
JP2003135075A (ja) * 2001-11-05 2003-05-13 Research Association For Biotechnology 新規な全長ｃＤＮＡ

Also Published As

Publication number Publication date
US20120171686A1 (en) 2012-07-05
EP2369517A2 (de) 2011-09-28
EP1783645A1 (de) 2007-05-09
AU2006311003B2 (en) 2012-11-08
DE602006019475D1 (de) 2011-02-17
WO2007054520A3 (en) 2007-08-09
US8116987B2 (en) 2012-02-14
AU2006311003A1 (en) 2007-05-18
US20090062135A1 (en) 2009-03-05
EP1952293B1 (de) 2011-01-05
CA2628941A1 (en) 2007-05-18
EP2369517A3 (de) 2012-01-11
WO2007054520A2 (en) 2007-05-18
EP1952293A2 (de) 2008-08-06

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