ATE494627T1 - Massenspektrometer mit doppelter ionenleiterschnittstelle und vorrichtung zur verwendung desselben - Google Patents

Massenspektrometer mit doppelter ionenleiterschnittstelle und vorrichtung zur verwendung desselben

Info

Publication number
ATE494627T1
ATE494627T1 AT00310626T AT00310626T ATE494627T1 AT E494627 T1 ATE494627 T1 AT E494627T1 AT 00310626 T AT00310626 T AT 00310626T AT 00310626 T AT00310626 T AT 00310626T AT E494627 T1 ATE494627 T1 AT E494627T1
Authority
AT
Austria
Prior art keywords
interface
same
mass spectrometer
ion conductor
mass analyzer
Prior art date
Application number
AT00310626T
Other languages
English (en)
Inventor
Keqi Tang
Alan E Schoen
Jean-Jacques Dunyach
Original Assignee
Thermo Finnigan Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Finnigan Llc filed Critical Thermo Finnigan Llc
Application granted granted Critical
Publication of ATE494627T1 publication Critical patent/ATE494627T1/de

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/044—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for preventing droplets from entering the analyzer; Desolvation of droplets
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/067—Ion lenses, apertures, skimmers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
AT00310626T 1999-12-03 2000-11-30 Massenspektrometer mit doppelter ionenleiterschnittstelle und vorrichtung zur verwendung desselben ATE494627T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45427399A 1999-12-03 1999-12-03
US09/715,815 US6528784B1 (en) 1999-12-03 2000-11-16 Mass spectrometer system including a double ion guide interface and method of operation

Publications (1)

Publication Number Publication Date
ATE494627T1 true ATE494627T1 (de) 2011-01-15

Family

ID=27037405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00310626T ATE494627T1 (de) 1999-12-03 2000-11-30 Massenspektrometer mit doppelter ionenleiterschnittstelle und vorrichtung zur verwendung desselben

Country Status (6)

Country Link
US (2) US6528784B1 (de)
EP (2) EP2302660A1 (de)
JP (1) JP4467786B2 (de)
AT (1) ATE494627T1 (de)
CA (1) CA2327135C (de)
DE (1) DE60045470D1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9820210D0 (en) 1998-09-16 1998-11-11 Vg Elemental Limited Means for removing unwanted ions from an ion transport system and mass spectrometer
US6528784B1 (en) * 1999-12-03 2003-03-04 Thermo Finnigan Llc Mass spectrometer system including a double ion guide interface and method of operation
US6720554B2 (en) * 2000-07-21 2004-04-13 Mds Inc. Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps
US7060972B2 (en) * 2000-07-21 2006-06-13 Mds Inc. Triple quadrupole mass spectrometer with capability to perform multiple mass analysis steps
US6700120B2 (en) * 2000-11-30 2004-03-02 Mds Inc. Method for improving signal-to-noise ratios for atmospheric pressure ionization mass spectrometry
US6451089B1 (en) * 2001-07-25 2002-09-17 Phelps Dodge Corporation Process for direct electrowinning of copper
GB0201914D0 (en) * 2002-01-29 2002-03-13 Univ Liverpool Improvements in and relating to quadrupole mass spectrometers
GB0210930D0 (en) 2002-05-13 2002-06-19 Thermo Electron Corp Improved mass spectrometer and mass filters therefor
US7041968B2 (en) * 2003-03-20 2006-05-09 Science & Technology Corporation @ Unm Distance of flight spectrometer for MS and simultaneous scanless MS/MS
US7947950B2 (en) * 2003-03-20 2011-05-24 Stc.Unm Energy focus for distance of flight mass spectometry with constant momentum acceleration and an ion mirror
US7019290B2 (en) * 2003-05-30 2006-03-28 Applera Corporation System and method for modifying the fringing fields of a radio frequency multipole
US6998622B1 (en) * 2004-11-17 2006-02-14 Agilent Technologies, Inc. On-axis electron impact ion source
US7256395B2 (en) * 2005-01-10 2007-08-14 Applera Corporation Method and apparatus for improved sensitivity in a mass spectrometer
US7259371B2 (en) * 2005-01-10 2007-08-21 Applera Corporation Method and apparatus for improved sensitivity in a mass spectrometer
WO2007030948A1 (en) * 2005-09-15 2007-03-22 Phenomenome Discoveries Inc. Method and apparatus for fourier transform ion cyclotron resonance mass spectrometry
CA2632251C (en) * 2005-12-22 2011-06-21 Thermo Finnigan Llc Apparatus and method for pumping in an ion optical device
EP1984934A4 (de) * 2006-02-08 2015-01-14 Dh Technologies Dev Pte Ltd Hochfrequenzionenführung
US7459678B2 (en) * 2006-05-12 2008-12-02 Thermo Finnigan Llc Switchable branched ion guide
US7391019B2 (en) * 2006-07-21 2008-06-24 Thermo Finnigan Llc Electrospray ion source
GB2489623B (en) * 2007-09-07 2013-03-06 Ionics Mass Spectrometry Group Multi-pressure stage mass spectrometer and methods
US8288716B2 (en) * 2009-04-06 2012-10-16 Ut-Battelle, Llc Real-time airborne particle analyzer
US8324565B2 (en) * 2009-12-17 2012-12-04 Agilent Technologies, Inc. Ion funnel for mass spectrometry
JP5726205B2 (ja) * 2009-12-18 2015-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド イオンを処理する方法
EP2498273A1 (de) 2011-03-07 2012-09-12 Tofwerk AG Massenspektrometer
US8829435B2 (en) * 2011-08-01 2014-09-09 Thermo Finnigan Llc Moldable ceramics for mass spectrometry applications
CA2849453C (en) 2011-09-22 2020-10-27 Purdue Research Foundation Differentially pumped dual linear quadrupole ion trap mass spectrometer
JP5673848B2 (ja) 2011-10-20 2015-02-18 株式会社島津製作所 質量分析装置
US10229824B2 (en) * 2013-03-11 2019-03-12 1St Detect Corporation Chemical analysis instrument with multi-purpose pump
CN205984893U (zh) 2013-05-30 2017-02-22 珀金埃尔默健康科学股份有限公司 反射器、透镜及包括透镜的套件
WO2014194172A2 (en) 2013-05-31 2014-12-04 Perkinelmer Health Sciences, Inc. Time of flight tubes and methods of using them
US10090138B2 (en) 2013-05-31 2018-10-02 Micromass Uk Limited Compact mass spectrometer
WO2014191746A1 (en) 2013-05-31 2014-12-04 Micromass Uk Limited Compact mass spectrometer
WO2014191750A1 (en) 2013-05-31 2014-12-04 Micromass Uk Limited Compact mass spectrometer
WO2014191748A1 (en) 2013-05-31 2014-12-04 Micromass Uk Limited Compact mass spectrometer
WO2014197341A2 (en) * 2013-06-02 2014-12-11 Perkinelmer Health Sciences, Inc. Collision cells and methods using them
EP3005401B1 (de) 2013-06-03 2022-04-06 PerkinElmer Health Sciences, Inc. Ionenleiter oder -filter mit ausgewählter gasleitfähigkeit
CN105655224B (zh) * 2016-03-09 2018-02-09 清华大学 一种小型化的二级真空矩型离子阱质谱仪及其检测方法
US10804088B1 (en) 2019-05-30 2020-10-13 Thermo Finnigan Llc Methods and system for optimizing ion transmission through a mass spectrometer
EP4128316A1 (de) * 2020-03-24 2023-02-08 DH Technologies Development PTE. Ltd. Dreistufige atmosphäre für vakuum-massenspektrometereinlass mit zusätzlicher clusterbildung in der dritten stufe
GB202004961D0 (en) 2020-04-03 2020-05-20 Micromass Ltd De-clustering guide
CN111933512B (zh) * 2020-07-08 2022-04-05 中国计量科学研究院 一种新型四极杆-离子阱串联质谱离子存储系统及方法

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA585694A (en) 1959-10-27 Van Antwerpen Martin Slitting machine
US1969399A (en) 1930-03-03 1934-08-07 Television Lab Inc Electron multiplier
US3555273A (en) 1968-07-18 1971-01-12 Varian Associates Mass filter apparatus having an electric field the equipotentials of which are three dimensionally hyperbolic
US4023398A (en) 1975-03-03 1977-05-17 John Barry French Apparatus for analyzing trace components
US4423324A (en) 1977-04-22 1983-12-27 Finnigan Corporation Apparatus for detecting negative ions
US4148196A (en) 1977-04-25 1979-04-10 Sciex Inc. Multiple stage cryogenic pump and method of pumping
CA1134957A (en) 1979-08-03 1982-11-02 Mds Health Group Limited Tandem mass spectrometer with synchronized rf fields
US4328420A (en) 1980-07-28 1982-05-04 French John B Tandem mass spectrometer with open structure AC-only rod sections, and method of operating a mass spectrometer system
US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
GB8305228D0 (en) 1983-02-25 1983-03-30 Vg Instr Ltd Operating quadrupole mass spectrometers
EP0409362B1 (de) 1985-05-24 1995-04-19 Finnigan Corporation Betriebsverfahren für eine Ionenfalle
US5107109A (en) 1986-03-07 1992-04-21 Finnigan Corporation Method of increasing the dynamic range and sensitivity of a quadrupole ion trap mass spectrometer
US4791292A (en) 1986-04-24 1988-12-13 The Dow Chemical Company Capillary membrane interface for a mass spectrometer
US4755670A (en) 1986-10-01 1988-07-05 Finnigan Corporation Fourtier transform quadrupole mass spectrometer and method
US4842701A (en) 1987-04-06 1989-06-27 Battelle Memorial Institute Combined electrophoretic-separation and electrospray method and system
US5026987A (en) 1988-06-02 1991-06-25 Purdue Research Foundation Mass spectrometer with in-line collision surface means
JP2765890B2 (ja) 1988-12-09 1998-06-18 株式会社日立製作所 プラズマイオン源微量元素質量分析装置
CA1307859C (en) 1988-12-12 1992-09-22 Donald James Douglas Mass spectrometer and method with improved ion transmission
US4977320A (en) 1990-01-22 1990-12-11 The Rockefeller University Electrospray ionization mass spectrometer with new features
JPH04171650A (ja) 1990-11-02 1992-06-18 Hitachi Ltd 質量分析計
US5162650A (en) 1991-01-25 1992-11-10 Finnigan Corporation Method and apparatus for multi-stage particle separation with gas addition for a mass spectrometer
US5206506A (en) 1991-02-12 1993-04-27 Kirchner Nicholas J Ion processing: control and analysis
US5182451A (en) 1991-04-30 1993-01-26 Finnigan Corporation Method of operating an ion trap mass spectrometer in a high resolution mode
US5089703A (en) 1991-05-16 1992-02-18 Finnigan Corporation Method and apparatus for mass analysis in a multipole mass spectrometer
US5157260A (en) 1991-05-17 1992-10-20 Finnian Corporation Method and apparatus for focusing ions in viscous flow jet expansion region of an electrospray apparatus
US5179278A (en) 1991-08-23 1993-01-12 Mds Health Group Limited Multipole inlet system for ion traps
JP2913924B2 (ja) * 1991-09-12 1999-06-28 株式会社日立製作所 質量分析の方法および装置
US5304798A (en) * 1992-04-10 1994-04-19 Millipore Corporation Housing for converting an electrospray to an ion stream
US5432343A (en) 1993-06-03 1995-07-11 Gulcicek; Erol E. Ion focusing lensing system for a mass spectrometer interfaced to an atmospheric pressure ion source
US5412208A (en) 1994-01-13 1995-05-02 Mds Health Group Limited Ion spray with intersecting flow
US6011259A (en) * 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
AU1932095A (en) * 1994-02-28 1995-09-11 Analytica Of Branford, Inc. Multipole ion guide for mass spectrometry
US5538897A (en) 1994-03-14 1996-07-23 University Of Washington Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases
US5420425A (en) 1994-05-27 1995-05-30 Finnigan Corporation Ion trap mass spectrometer system and method
US5670378A (en) 1995-02-23 1997-09-23 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for trace oxygen detection
US5572022A (en) 1995-03-03 1996-11-05 Finnigan Corporation Method and apparatus of increasing dynamic range and sensitivity of a mass spectrometer
JP2953344B2 (ja) 1995-04-28 1999-09-27 株式会社島津製作所 液体クロマトグラフ質量分析装置
DE19520319A1 (de) 1995-06-02 1996-12-12 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für die Einführung von Ionen in Quadrupol-Ionenfallen
DE19520276C2 (de) 1995-06-02 1999-08-26 Bruker Daltonik Gmbh Vorrichtung für die Einführung von Ionen in ein Massenspektrometer
AU6653296A (en) 1995-08-11 1997-03-12 Mds Health Group Limited Spectrometer with axial field
US5811800A (en) 1995-09-14 1998-09-22 Bruker-Franzen Analytik Gmbh Temporary storage of ions for mass spectrometric analyses
US6259091B1 (en) 1996-01-05 2001-07-10 Battelle Memorial Institute Apparatus for reduction of selected ion intensities in confined ion beams
US5767512A (en) 1996-01-05 1998-06-16 Battelle Memorial Institute Method for reduction of selected ion intensities in confined ion beams
US5750993A (en) 1996-05-09 1998-05-12 Finnigan Corporation Method of reducing noise in an ion trap mass spectrometer coupled to an atmospheric pressure ionization source
GB9612070D0 (en) 1996-06-10 1996-08-14 Micromass Ltd Plasma mass spectrometer
US5852294A (en) 1996-07-03 1998-12-22 Analytica Of Branford, Inc. Multiple rod construction for ion guides and mass spectrometers
US5756996A (en) 1996-07-05 1998-05-26 Finnigan Corporation Ion source assembly for an ion trap mass spectrometer and method
US6140638A (en) * 1997-06-04 2000-10-31 Mds Inc. Bandpass reactive collision cell
GB9717926D0 (en) * 1997-08-22 1997-10-29 Micromass Ltd Methods and apparatus for tandem mass spectrometry
US6015972A (en) 1998-01-12 2000-01-18 Mds Inc. Boundary activated dissociation in rod-type mass spectrometer
US6331702B1 (en) 1999-01-25 2001-12-18 University Of Manitoba Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use
US6987264B1 (en) 1998-01-23 2006-01-17 Analytica Of Branford, Inc. Mass spectrometry with multipole ion guides
US6753523B1 (en) 1998-01-23 2004-06-22 Analytica Of Branford, Inc. Mass spectrometry with multipole ion guides
JP3052929B2 (ja) 1998-04-24 2000-06-19 株式会社日立製作所 質量分析装置
US6124591A (en) 1998-10-16 2000-09-26 Finnigan Corporation Method of ion fragmentation in a quadrupole ion trap
US6528784B1 (en) * 1999-12-03 2003-03-04 Thermo Finnigan Llc Mass spectrometer system including a double ion guide interface and method of operation
US6700120B2 (en) 2000-11-30 2004-03-02 Mds Inc. Method for improving signal-to-noise ratios for atmospheric pressure ionization mass spectrometry

Also Published As

Publication number Publication date
USRE40632E1 (en) 2009-02-03
EP1109198A3 (de) 2005-11-16
US6528784B1 (en) 2003-03-04
EP2302660A1 (de) 2011-03-30
JP2002083565A (ja) 2002-03-22
EP1109198B1 (de) 2011-01-05
JP4467786B2 (ja) 2010-05-26
DE60045470D1 (de) 2011-02-17
CA2327135A1 (en) 2001-06-03
CA2327135C (en) 2004-01-27
EP1109198A2 (de) 2001-06-20

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