ATE494908T1 - Pflanzen lektine als mukosale adjuvantien - Google Patents

Pflanzen lektine als mukosale adjuvantien

Info

Publication number
ATE494908T1
ATE494908T1 AT00988507T AT00988507T ATE494908T1 AT E494908 T1 ATE494908 T1 AT E494908T1 AT 00988507 T AT00988507 T AT 00988507T AT 00988507 T AT00988507 T AT 00988507T AT E494908 T1 ATE494908 T1 AT E494908T1
Authority
AT
Austria
Prior art keywords
lectins
plants
mucosal adjuvants
immunogen
mammal
Prior art date
Application number
AT00988507T
Other languages
English (en)
Inventor
Edward Lavelle
Derek O'hagan
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE494908T1 publication Critical patent/ATE494908T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT00988507T 1999-10-26 2000-10-26 Pflanzen lektine als mukosale adjuvantien ATE494908T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16137199P 1999-10-26 1999-10-26
PCT/US2000/041539 WO2001034193A1 (en) 1999-10-26 2000-10-26 Plant lectins as mucosal adjuvants

Publications (1)

Publication Number Publication Date
ATE494908T1 true ATE494908T1 (de) 2011-01-15

Family

ID=22580920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00988507T ATE494908T1 (de) 1999-10-26 2000-10-26 Pflanzen lektine als mukosale adjuvantien

Country Status (8)

Country Link
EP (1) EP1221972B1 (de)
JP (2) JP5072159B2 (de)
AT (1) ATE494908T1 (de)
AU (1) AU2471201A (de)
CA (1) CA2389080C (de)
DE (1) DE60045516D1 (de)
ES (1) ES2356890T3 (de)
WO (1) WO2001034193A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1341811E (pt) * 2000-11-14 2008-06-04 Ian Pryme Preparação de lectinas do visco ingerível por via oral e método
AU2004268497A1 (en) * 2003-02-28 2005-03-10 Antigenics Inc. Use of lectins to promote oligomerization of glycoproteins and antigenic molecules
DE102011003478A1 (de) 2011-02-01 2012-08-02 Cytavis Biopharma Gmbh Antivirales Mittel enthaltend rekombinante Mistellektine
CA2840335C (en) * 2011-06-27 2021-02-16 Cytavis Biopharma Gmbh Recombinant mistletoe lectin and use thereof as an adjuvant

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5668614A (en) * 1979-11-09 1981-06-09 Eisai Co Ltd Abrin-containing agent for immunological enhancement
JPS60197628A (ja) * 1984-03-22 1985-10-07 Eisai Co Ltd マイコプラズマ性肺炎予防治療剤
IL78775A (en) * 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
US5707644A (en) 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
IT1253009B (it) 1991-12-31 1995-07-10 Sclavo Ricerca S R L Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
DE4221836A1 (de) * 1992-07-03 1994-01-05 Gabius Hans Joachim Prof Dr Das biochemisch aufgereinigte Mistel-Lektin (ML-1) als therapeutisch anwendbarer Immunmodulator
US5603960A (en) 1993-05-25 1997-02-18 O'hagan; Derek T. Preparation of microparticles and method of immunization
US5744155A (en) 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
GB9603314D0 (en) 1996-02-16 1996-04-17 Biocine Spa Immunogenic detoxified mutant toxins
US5955097A (en) 1996-10-18 1999-09-21 Virotex Corporation Pharmaceutical preparation applicable to mucosal surfaces and body tissues
US5800832A (en) 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
US5814329A (en) 1996-11-12 1998-09-29 Polytherapeutics, Inc. Hydrophilic polystyrene graft copolymer vehicle for intravaginal administration of pharmacologically active agents
US6876761B1 (en) 1997-08-08 2005-04-05 Matsushita Electric Industrial Co., Ltd. Jig for calibrating component recognition apparatus, component recognition calibrating method using the jig, and component mounting apparatus using the jig
US5968554A (en) 1998-07-07 1999-10-19 Cascade Development, Inc. A Subsidiary Of Cardinal Health, Inc. Sustained release pharmaceutical preparation
CN102847538B (zh) 2007-07-06 2016-07-06 M技术株式会社 由球碳形成的结晶的制造方法及制造装置
US9287659B2 (en) 2012-10-16 2016-03-15 Corning Optical Communications Rf Llc Coaxial cable connector with integral RFI protection
KR102344533B1 (ko) 2015-02-12 2021-12-29 엘지이노텍 주식회사 발광소자 패키지

Also Published As

Publication number Publication date
WO2001034193A9 (en) 2002-12-05
CA2389080A1 (en) 2001-05-17
ES2356890T3 (es) 2011-04-14
AU2471201A (en) 2001-06-06
DE60045516D1 (de) 2011-02-24
EP1221972B1 (de) 2011-01-12
WO2001034193A1 (en) 2001-05-17
CA2389080C (en) 2012-02-21
EP1221972A1 (de) 2002-07-17
JP2011098986A (ja) 2011-05-19
JP5072159B2 (ja) 2012-11-14
JP2003513936A (ja) 2003-04-15

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