ATE496627T1 - Mischzell-populationen für die gewebereparatur und trenntechnik für die zellaufbereitung - Google Patents

Mischzell-populationen für die gewebereparatur und trenntechnik für die zellaufbereitung

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Publication number
ATE496627T1
ATE496627T1 AT07867360T AT07867360T ATE496627T1 AT E496627 T1 ATE496627 T1 AT E496627T1 AT 07867360 T AT07867360 T AT 07867360T AT 07867360 T AT07867360 T AT 07867360T AT E496627 T1 ATE496627 T1 AT E496627T1
Authority
AT
Austria
Prior art keywords
biochamber
cells
enzyme
tissue repair
rinse solution
Prior art date
Application number
AT07867360T
Other languages
English (en)
Inventor
Brian Hampson
Kristin Goltry
Douglas M Smith
Jonathan A Rowley
Naia Venturi
Original Assignee
Aastrom Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aastrom Biosciences Inc filed Critical Aastrom Biosciences Inc
Application granted granted Critical
Publication of ATE496627T1 publication Critical patent/ATE496627T1/de

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61P13/12Drugs for disorders of the urinary system of the kidneys
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    • A61P19/00Drugs for skeletal disorders
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0645Macrophages, e.g. Kuepfer cells in the liver; Monocytes
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0669Bone marrow stromal cells; Whole bone marrow
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/80Undefined extracts from animals
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    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes

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  • Vascular Medicine (AREA)
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  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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AT07867360T 2006-11-03 2007-11-05 Mischzell-populationen für die gewebereparatur und trenntechnik für die zellaufbereitung ATE496627T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85650406P 2006-11-03 2006-11-03
US93270207P 2007-06-01 2007-06-01
PCT/US2007/023302 WO2008054825A2 (en) 2006-11-03 2007-11-05 Mixed cell populations for tissue repair and separation technique for cell processing

Publications (1)

Publication Number Publication Date
ATE496627T1 true ATE496627T1 (de) 2011-02-15

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Country Link
US (5) US7871605B2 (de)
EP (3) EP2086556B1 (de)
JP (4) JP5537153B2 (de)
AT (1) ATE496627T1 (de)
AU (1) AU2007314299B2 (de)
CA (2) CA2913024A1 (de)
DE (1) DE602007012290D1 (de)
DK (2) DK2086556T3 (de)
ES (2) ES2441560T3 (de)
WO (1) WO2008054825A2 (de)

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DK2086556T3 (da) 2011-05-09
JP5767672B2 (ja) 2015-08-19
US8394631B2 (en) 2013-03-12
US20110124105A1 (en) 2011-05-26
US7871605B2 (en) 2011-01-18
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WO2008054825A2 (en) 2008-05-08
DE602007012290D1 (de) 2011-03-10
CA2668330A1 (en) 2008-05-08
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US20160317584A1 (en) 2016-11-03
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US8158122B2 (en) 2012-04-17
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US20130209420A1 (en) 2013-08-15
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EP2086556B1 (de) 2011-01-26
JP2015110652A (ja) 2015-06-18
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