ATE496891T1 - ARYLPIPERAZINE DERIVATIVES SUITABLE FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS - Google Patents
ARYLPIPERAZINE DERIVATIVES SUITABLE FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERSInfo
- Publication number
- ATE496891T1 ATE496891T1 AT07821255T AT07821255T ATE496891T1 AT E496891 T1 ATE496891 T1 AT E496891T1 AT 07821255 T AT07821255 T AT 07821255T AT 07821255 T AT07821255 T AT 07821255T AT E496891 T1 ATE496891 T1 AT E496891T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- neuropsychiatric disorders
- derivatives suitable
- arylpiperazine derivatives
- arylpiperazine
- Prior art date
Links
- -1 aryl piperazine derivatives Chemical class 0.000 abstract 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- 102000049773 5-HT2A Serotonin Receptor Human genes 0.000 abstract 1
- 108010072564 5-HT2A Serotonin Receptor Proteins 0.000 abstract 1
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
- 102000040125 5-hydroxytryptamine receptor family Human genes 0.000 abstract 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 1
- 102000015554 Dopamine receptor Human genes 0.000 abstract 1
- 108050004812 Dopamine receptor Proteins 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention provides novel aryl piperazine derivatives represented by Formula (I) having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, 5HT1A and 5-HT2A receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders, incl. schizophrenia.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85131006P | 2006-10-13 | 2006-10-13 | |
| DKPA200601328 | 2006-10-13 | ||
| PCT/EP2007/060888 WO2008043839A1 (en) | 2006-10-13 | 2007-10-12 | Aryl piperazine derivatives useful for the treatment of neuropsychiatry disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496891T1 true ATE496891T1 (en) | 2011-02-15 |
Family
ID=41284131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07821255T ATE496891T1 (en) | 2006-10-13 | 2007-10-12 | ARYLPIPERAZINE DERIVATIVES SUITABLE FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101568524A (en) |
| AT (1) | ATE496891T1 (en) |
| DE (1) | DE602007012285D1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12319659B2 (en) | 2017-02-24 | 2025-06-03 | Shenzhen Linglan Bio-Pharmaceutical Technology Co., Ltd | Selective ligand for dopamine D3 receptor, preparation method therefor, and pharmaceutical application thereof |
-
2007
- 2007-10-12 AT AT07821255T patent/ATE496891T1/en not_active IP Right Cessation
- 2007-10-12 DE DE602007012285T patent/DE602007012285D1/en active Active
- 2007-10-12 CN CNA200780038217XA patent/CN101568524A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE602007012285D1 (en) | 2011-03-10 |
| CN101568524A (en) | 2009-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |