ATE496903T1 - Thiophenderivate als medikamente zur behandlung von okularer hypertonie - Google Patents

Thiophenderivate als medikamente zur behandlung von okularer hypertonie

Info

Publication number
ATE496903T1
ATE496903T1 AT08728492T AT08728492T ATE496903T1 AT E496903 T1 ATE496903 T1 AT E496903T1 AT 08728492 T AT08728492 T AT 08728492T AT 08728492 T AT08728492 T AT 08728492T AT E496903 T1 ATE496903 T1 AT E496903T1
Authority
AT
Austria
Prior art keywords
treatment
medications
thiophene derivatives
occular hypertension
hypertension
Prior art date
Application number
AT08728492T
Other languages
English (en)
Inventor
Brent Johnson
David Old
Yariv Donde
Robert Burk
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of ATE496903T1 publication Critical patent/ATE496903T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT08728492T 2007-02-01 2008-01-30 Thiophenderivate als medikamente zur behandlung von okularer hypertonie ATE496903T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88775907P 2007-02-01 2007-02-01
PCT/US2008/052375 WO2008094958A1 (en) 2007-02-01 2008-01-30 Thiophene derivatives useful as medicaments for treating ocular hypertension

Publications (1)

Publication Number Publication Date
ATE496903T1 true ATE496903T1 (de) 2011-02-15

Family

ID=39430728

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08728492T ATE496903T1 (de) 2007-02-01 2008-01-30 Thiophenderivate als medikamente zur behandlung von okularer hypertonie

Country Status (6)

Country Link
US (1) US7960431B2 (de)
EP (1) EP2125773B1 (de)
AT (1) ATE496903T1 (de)
DE (1) DE602008004741D1 (de)
ES (1) ES2358558T3 (de)
WO (1) WO2008094958A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010005105A (es) 2007-11-09 2010-05-27 Allergan Inc Ciclopentanos substituidos que comprenden actividad de prostaglandina.
US9090584B2 (en) 2010-01-26 2015-07-28 Allergan, Inc. Therapeutic agents for treatment of ocular hypertension
US8299068B2 (en) 2010-01-29 2012-10-30 Allergan, Inc. Therapeutically active cyclopentanes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688819A (en) * 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
WO2000051977A1 (en) * 1999-03-05 2000-09-08 The Procter & Gamble Company Aldehyde intermediates for the preparation of prostaglandin derivatives
ATE281432T1 (de) * 1999-03-05 2004-11-15 Univ Duke C-16 ungesätigte fp-selektive prostaglandin analoge
IL143477A (en) 2001-05-31 2009-07-20 Finetech Pharmaceutical Ltd Process for the preparation of 17-phenyl-18,19,20-trinor-pgf2?? and its derivatives
US7166730B2 (en) 2000-01-27 2007-01-23 Fine Tech Laboratories, Ltd Process for the preparation of prostaglandin derivatives
US7183310B2 (en) * 2004-08-10 2007-02-27 Allergan, Inc. Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US7101904B2 (en) * 2004-08-10 2006-09-05 Allergan, Inc. Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents
WO2007149829A2 (en) * 2006-06-20 2007-12-27 Allergan, Inc. Therapeutic compounds

Also Published As

Publication number Publication date
WO2008094958A1 (en) 2008-08-07
EP2125773A1 (de) 2009-12-02
EP2125773B1 (de) 2011-01-26
US7960431B2 (en) 2011-06-14
DE602008004741D1 (de) 2011-03-10
ES2358558T3 (es) 2011-05-11
US20100173981A1 (en) 2010-07-08

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties