ATE496993T1 - Transformierte saccharomyces cerevisiae sowie verfahren zur massenproduktion des proteins lk8 damit - Google Patents
Transformierte saccharomyces cerevisiae sowie verfahren zur massenproduktion des proteins lk8 damitInfo
- Publication number
- ATE496993T1 ATE496993T1 AT05726252T AT05726252T ATE496993T1 AT E496993 T1 ATE496993 T1 AT E496993T1 AT 05726252 T AT05726252 T AT 05726252T AT 05726252 T AT05726252 T AT 05726252T AT E496993 T1 ATE496993 T1 AT E496993T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- saccharomyces cerevisiae
- mass production
- transformed saccharomyces
- transformed
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 title abstract 2
- VEEGZPWAAPPXRB-BJMVGYQFSA-N (3e)-3-(1h-imidazol-5-ylmethylidene)-1h-indol-2-one Chemical compound O=C1NC2=CC=CC=C2\C1=C/C1=CN=CN1 VEEGZPWAAPPXRB-BJMVGYQFSA-N 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 229940121369 angiogenesis inhibitor Drugs 0.000 abstract 1
- 239000004037 angiogenesis inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020040005033A KR100595864B1 (ko) | 2004-01-27 | 2004-01-27 | 형질전환 사카로마이세스 세레비지애 균주 및 이를 이용한lk8 단백질의 생산방법 |
| PCT/KR2005/000214 WO2005071074A1 (en) | 2004-01-27 | 2005-01-26 | Transformed saccharomyces cerevisiae and method for mass-production of lk8 protein using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496993T1 true ATE496993T1 (de) | 2011-02-15 |
Family
ID=36968296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05726252T ATE496993T1 (de) | 2004-01-27 | 2005-01-26 | Transformierte saccharomyces cerevisiae sowie verfahren zur massenproduktion des proteins lk8 damit |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7858361B2 (de) |
| EP (1) | EP1711603B1 (de) |
| JP (1) | JP4465363B2 (de) |
| KR (1) | KR100595864B1 (de) |
| CN (1) | CN1914317B (de) |
| AT (1) | ATE496993T1 (de) |
| DE (1) | DE602005026099D1 (de) |
| ES (1) | ES2356641T3 (de) |
| WO (1) | WO2005071074A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100649102B1 (ko) * | 2004-08-23 | 2006-11-24 | 이재화 | 루코신a의 생산방법 |
| KR100764839B1 (ko) * | 2006-04-25 | 2007-10-09 | 재단법인 목암생명공학연구소 | Lk8 단백질 생산용 사카로마이세스 세레비지애 |
| US8298787B2 (en) | 2006-06-20 | 2012-10-30 | Mogam Biotechnology Research Institute | Methods for enhancing a secretion efficiency of recombinant foreign protein in yeast expression system |
| KR100888022B1 (ko) * | 2006-12-21 | 2009-03-09 | 재단법인 목암생명공학연구소 | 면역글로불린 Fc와 인간 아포리포단백질(a)크링글절편의 융합단백질 LK8Fc |
| EP2722389B1 (de) | 2011-06-15 | 2018-03-07 | Hong Jin Kim | Verfahren zur steigerung der produktionsausbeute des menschlichen papillomavirus-proteins l1 |
| EP3184639B1 (de) * | 2014-08-21 | 2019-06-12 | Chung-Ang University Industry-Academy Cooperation Foundation | Auf rdna-nts basiertes einsatzkassettenset mit mehreren genen und rekombinanter hefestamm von gras-qualität |
| EP3368549B1 (de) | 2015-10-26 | 2022-11-30 | Council of Scientific and Industrial Research | Genetisch modifizierte hefezelle und verbessertes verfahren zur herstellung von gerinnselspezifischer streptokinase |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7270969B2 (en) * | 1999-05-05 | 2007-09-18 | Phylogica Limited | Methods of constructing and screening diverse expression libraries |
| CA2384929C (en) * | 1999-09-15 | 2006-12-05 | Mogam Biotechnology Research Institute | A novel angiogenesis inhibitor |
| EP1343903B1 (de) * | 2000-12-21 | 2007-11-14 | Thromb-X N.V. | Hefeexpressionsvektor und verfahren zur herstellung eines rekombinanten proteins durch expression in einer hefezelle |
| CA2455558A1 (en) * | 2001-07-25 | 2003-02-06 | Intier Automotive Inc. | Sliding sun visor |
| KR100681762B1 (ko) * | 2004-01-09 | 2007-02-15 | 재단법인 목암생명공학연구소 | 인간 아포리포단백질(a) 크링글 LK68 또는 LK8유전자를 유효성분으로 함유하는 항암 치료제 및 그를이용한 암 치료방법 |
-
2004
- 2004-01-27 KR KR1020040005033A patent/KR100595864B1/ko not_active Expired - Fee Related
-
2005
- 2005-01-26 AT AT05726252T patent/ATE496993T1/de not_active IP Right Cessation
- 2005-01-26 ES ES05726252T patent/ES2356641T3/es not_active Expired - Lifetime
- 2005-01-26 JP JP2006550943A patent/JP4465363B2/ja not_active Expired - Fee Related
- 2005-01-26 EP EP05726252A patent/EP1711603B1/de not_active Expired - Lifetime
- 2005-01-26 US US10/587,155 patent/US7858361B2/en not_active Expired - Fee Related
- 2005-01-26 CN CN2005800032815A patent/CN1914317B/zh not_active Expired - Fee Related
- 2005-01-26 WO PCT/KR2005/000214 patent/WO2005071074A1/en not_active Ceased
- 2005-01-26 DE DE602005026099T patent/DE602005026099D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005071074A1 (en) | 2005-08-04 |
| DE602005026099D1 (de) | 2011-03-10 |
| EP1711603A4 (de) | 2007-07-25 |
| EP1711603A1 (de) | 2006-10-18 |
| CN1914317A (zh) | 2007-02-14 |
| JP4465363B2 (ja) | 2010-05-19 |
| ES2356641T3 (es) | 2011-04-11 |
| EP1711603B1 (de) | 2011-01-26 |
| KR20050077399A (ko) | 2005-08-02 |
| US20080187940A1 (en) | 2008-08-07 |
| US7858361B2 (en) | 2010-12-28 |
| CN1914317B (zh) | 2011-10-05 |
| KR100595864B1 (ko) | 2006-06-30 |
| JP2007519417A (ja) | 2007-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |