ATE497004T1 - Moraxella catarrhalis antigene uspa1 und uspa2 - Google Patents

Moraxella catarrhalis antigene uspa1 und uspa2

Info

Publication number
ATE497004T1
ATE497004T1 AT97953461T AT97953461T ATE497004T1 AT E497004 T1 ATE497004 T1 AT E497004T1 AT 97953461 T AT97953461 T AT 97953461T AT 97953461 T AT97953461 T AT 97953461T AT E497004 T1 ATE497004 T1 AT E497004T1
Authority
AT
Austria
Prior art keywords
uspa2
uspa1
moraxella catarrhalis
catarrhalis antigens
proteins
Prior art date
Application number
AT97953461T
Other languages
English (en)
Inventor
Eric Hansen
Christoph Aebi
Leslie Cope
Isobel Maciver
Michael Fiske
Ross Fredenburg
Original Assignee
Univ Texas
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Wyeth Corp filed Critical Univ Texas
Application granted granted Critical
Publication of ATE497004T1 publication Critical patent/ATE497004T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C07K14/212Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Gram-negative bacteria
    • C07K16/1217Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97953461T 1996-12-20 1997-12-19 Moraxella catarrhalis antigene uspa1 und uspa2 ATE497004T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3359896P 1996-12-20 1996-12-20
PCT/US1997/023930 WO1998028333A2 (en) 1996-12-20 1997-12-19 USPA1 AND USPA2 ANTIGENS OF $i(MORAXELLA CATARRHALIS)

Publications (1)

Publication Number Publication Date
ATE497004T1 true ATE497004T1 (de) 2011-02-15

Family

ID=21871324

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97953461T ATE497004T1 (de) 1996-12-20 1997-12-19 Moraxella catarrhalis antigene uspa1 und uspa2

Country Status (11)

Country Link
US (6) US6310190B1 (de)
EP (1) EP0948625B1 (de)
JP (2) JP2001515467A (de)
KR (1) KR100615109B1 (de)
CN (1) CN1159441C (de)
AT (1) ATE497004T1 (de)
AU (2) AU746442B2 (de)
BR (1) BR9714160A (de)
CA (1) CA2274495C (de)
DE (1) DE69740108D1 (de)
WO (1) WO1998028333A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6440425B1 (en) * 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
CN100379757C (zh) * 1998-05-01 2008-04-09 希龙公司 脑膜炎奈瑟球菌抗原和组合物
GB9817824D0 (en) * 1998-08-14 1998-10-14 Smithkline Beecham Biolog Novel compounds
GB9820002D0 (en) * 1998-09-14 1998-11-04 Smithkline Beecham Biolog Novel compounds
GB9904559D0 (en) 1999-02-26 1999-04-21 Smithkline Beecham Biolog Novel compounds
WO2000061165A1 (en) * 1999-04-13 2000-10-19 Smithkline Beecham Corporation Conserved adhesin motif and methods of use thereof
EP1185658B1 (de) * 1999-05-24 2008-06-04 GlaxoSmithKline Biologicals S.A. Neue verbindungen aus moraxella catarrhalis
ES2281409T3 (es) 2000-02-28 2007-10-01 Novartis Vaccines And Diagnostics S.R.L. Expresion heterologa de proteinas de neisseria.
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
WO2002083710A2 (en) * 2001-04-13 2002-10-24 Wyeth Holdings Corporation Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
GB0222764D0 (en) * 2002-10-02 2002-11-06 Univ Bristol Therapeutic peptide
US7449302B2 (en) 2002-10-02 2008-11-11 The University Of Bristol, University Walk Therapeutic peptides
US7407672B2 (en) * 2002-11-04 2008-08-05 National Heart Center Composition derived from biological materials and method of use and preparation
EP1735446A2 (de) * 2004-04-15 2006-12-27 University Of Bristol Therapeutische peptide
KR102378962B1 (ko) 2005-04-08 2022-03-28 와이어쓰 엘엘씨 다가 폐렴구균 다당류-단백질 접합체 조성물
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US8092811B2 (en) * 2005-08-10 2012-01-10 Arne Forsgren Ab Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system
WO2008029271A2 (en) 2006-02-27 2008-03-13 Gal Markel Ceacam based antibacterial agents
US20090317834A1 (en) * 2006-03-08 2009-12-24 Jarmo Laine Novel cellular glycan compositions
EP2221062B1 (de) * 2007-11-02 2014-05-21 Nippon Zenyaku Kogyo Co., Ltd. Neues adjuvans
TW201302779A (zh) 2011-04-13 2013-01-16 Glaxosmithkline Biolog Sa 融合蛋白質及組合疫苗
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
TW201620927A (zh) 2014-02-24 2016-06-16 葛蘭素史密斯克藍生物品公司 Uspa2蛋白質構築體及其用途
CN105203754B (zh) * 2014-08-18 2017-02-01 董俊 基于磁性分离和量子点标记的卡他莫拉菌快速检测方法和试剂盒
CA3072018A1 (en) 2017-08-14 2019-02-21 Glaxosmithkline Biologicals Sa Methods of boosting immune responses
GB201803692D0 (en) * 2018-03-08 2018-04-25 Glaxosmithkline Biologicals Sa Immunogenic composition
CN110540594B (zh) * 2018-12-20 2021-05-11 湖北工业大学 基于卡他莫拉菌表面蛋白的乳胶微球免疫层析试纸的制备方法
CN110540964A (zh) * 2018-12-20 2019-12-06 湖北诺美华抗体药物技术有限公司 人卡他莫拉菌表面蛋白单克隆抗体及应用
US20230266317A1 (en) * 2019-09-11 2023-08-24 Glaxosmithkline Biologicals Sa Antigen binding protein and assays

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US5552146A (en) * 1991-08-15 1996-09-03 Board Of Regents, The University Of Texas System Methods and compositions relating to useful antigens of Moraxella catarrhalis
US5279721A (en) 1993-04-22 1994-01-18 Peter Schmid Apparatus and method for an automated electrophoresis system
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6440425B1 (en) 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella

Also Published As

Publication number Publication date
US6310190B1 (en) 2001-10-30
KR20000057575A (ko) 2000-09-25
JP2001515467A (ja) 2001-09-18
US7576194B2 (en) 2009-08-18
CN1159441C (zh) 2004-07-28
DE69740108D1 (de) 2011-03-10
US20050131221A1 (en) 2005-06-16
US7569683B2 (en) 2009-08-04
US20050137131A1 (en) 2005-06-23
CA2274495C (en) 2009-06-02
CN1251611A (zh) 2000-04-26
AU746442B2 (en) 2002-05-02
US20090118486A1 (en) 2009-05-07
BR9714160A (pt) 2000-05-02
EP0948625B1 (de) 2011-01-26
CA2274495A1 (en) 1998-07-02
US20030032772A1 (en) 2003-02-13
AU5720198A (en) 1998-07-17
KR100615109B1 (ko) 2006-08-22
EP0948625A2 (de) 1999-10-13
US7344724B2 (en) 2008-03-18
WO1998028333A3 (en) 1999-01-07
JP2009142276A (ja) 2009-07-02
US7288646B2 (en) 2007-10-30
AU2011201228A1 (en) 2011-04-14
US20090137788A1 (en) 2009-05-28
WO1998028333A2 (en) 1998-07-02
US6753417B2 (en) 2004-06-22

Similar Documents

Publication Publication Date Title
ATE497004T1 (de) Moraxella catarrhalis antigene uspa1 und uspa2
FI940681A0 (fi) Menetelmä ja koostumuksia, jotka liittyvät Moraxella catarrhalisin käyttökelpoisiin antigeeneihin
DE69526339D1 (de) Monoklonale antikörper, die an den vorläufer des tumorabstossantigen mage-1 anbinden, rekombinantes mage-1, und von mage-1 abgebieteteimmunogene peptide
EA199800973A1 (ru) Полипептид белка-106 наружной мембраны moraxella catarrhalis, последовательность гена и их применение
EA199700248A1 (ru) Выделенный по существу очищенный поверхностный антиген белковой природы neisseria и фрагмент этого антигена
MX9708438A (es) Proteina principal de la membrana externa de moraxella, de alto peso molecular.
EA200601715A1 (ru) Получение гуманизированных антител в [организме] трансгенных животных
BR9610872A (pt) Proteìna receptora de transferrina de moraxella
DE69330643D1 (de) Monoklonaler antikörper, welcher spezifisch an vaskularisiertes tumorendothelium bindet und verwendungen davon
SE9500418L (sv) Nya försvagade Pseudomonas aerugionos stammar
NO996514L (no) Overflateantigener og proteiner nyttige i sammensetninger for diagnose og forebygging av Lymesykdom
GB9016315D0 (en) Medicaments
RU2004108115A (ru) Рекомбинантные антитела и композиции, а также способы их создания и использования
DK0493446T3 (da) Behandling af autoimmunsygdom.
ATE133708T1 (de) Immunogenisches peptid von echinococcus granulosis, dafür kodierende dns sowie diagnostische und therapeutische verwendungen
SE9600434L (sv) Fusionsprotein, bakteriofag uttryckande proteinet, dessas användning samt hybridoma celler och monoklonaler producerade av cellerna
CA2137280A1 (fr) Clonage du gene codant pour la proteine gp28.5 de toxoplasma gondii; fragments peptidiques de cette proteine et leurs applications
NZ309172A (en) Neutralizing conformational epitopes of chicken anemia virus
Muthukkaruppan et al. Monoclonal antibodies against Salmonella porins: generation and characterization
DK0472706T3 (da) Induktion af beskyttelse mod viral infektion
DE69629304D1 (de) Membranproteine von leptospira
ES2316576T3 (es) Nueva proteina de union a inmunoglobulina d expuesta sobre la superficie procedente de moraxella catarrhalis.
VAN LEUVEN et al. A mouse monoclonal antibody to human α2-macroglobulin (α2M) crossreacts with α2M from mouse: Epitope mapping and characterization of subunit structure of murine α2M
DK0470989T3 (da) Anvendelse af monoklonale anti-beta2 mikroglobulin antistoffer
ATE549348T1 (de) Therapeutische, sich von uspa1 ableitende peptide

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties