ATE497497T1 - 1,2,4-triazolderivat, verfahren zu dessenherstellung, und dieses enthaltende pharmazeutische zusammensetzung - Google Patents
1,2,4-triazolderivat, verfahren zu dessenherstellung, und dieses enthaltende pharmazeutische zusammensetzungInfo
- Publication number
- ATE497497T1 ATE497497T1 AT03811548T AT03811548T ATE497497T1 AT E497497 T1 ATE497497 T1 AT E497497T1 AT 03811548 T AT03811548 T AT 03811548T AT 03811548 T AT03811548 T AT 03811548T AT E497497 T1 ATE497497 T1 AT E497497T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical composition
- composition containing
- production
- triazole derivative
- containing same
- Prior art date
Links
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical class C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- -1 3,4-methylenedioxyphenyl Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2002-0072688A KR100470075B1 (ko) | 2002-11-21 | 2002-11-21 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
| PCT/KR2003/001514 WO2004046121A1 (en) | 2002-11-21 | 2003-07-29 | 1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE497497T1 true ATE497497T1 (de) | 2011-02-15 |
Family
ID=36539274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03811548T ATE497497T1 (de) | 2002-11-21 | 2003-07-29 | 1,2,4-triazolderivat, verfahren zu dessenherstellung, und dieses enthaltende pharmazeutische zusammensetzung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6849652B1 (de) |
| EP (1) | EP1567508B1 (de) |
| JP (1) | JP4348300B2 (de) |
| KR (1) | KR100470075B1 (de) |
| CN (1) | CN100355738C (de) |
| AT (1) | ATE497497T1 (de) |
| AU (1) | AU2003256091A1 (de) |
| DE (1) | DE60335960D1 (de) |
| ES (1) | ES2357834T3 (de) |
| WO (1) | WO2004046121A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100491317B1 (ko) * | 2002-11-26 | 2005-05-24 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
| KR100470076B1 (ko) * | 2002-11-27 | 2005-02-05 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
| AR044503A1 (es) * | 2003-03-18 | 2005-09-14 | Merck & Co Inc | Triazoles sustituidos con biarilo como bloqueantes del canal de sodio |
| KR100576343B1 (ko) * | 2004-07-22 | 2006-05-03 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
| US20080161324A1 (en) * | 2006-09-14 | 2008-07-03 | Johansen Lisa M | Compositions and methods for treatment of viral diseases |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4075341A (en) * | 1974-05-24 | 1978-02-21 | Gruppo Lepetit S.P.A. | 2-Substituted phenyl-5-triazols [5,1-a] isoquinoline compounds |
| US4259504A (en) * | 1979-08-27 | 1981-03-31 | American Cyanamid Company | Substituted 1H-1,2,4-triazoles |
| EP0051084A1 (de) * | 1980-11-04 | 1982-05-12 | American Cyanamid Company | Substituierte 1H-1,2,4-Triazole |
| DE4240587A1 (de) * | 1992-12-03 | 1994-06-09 | Bayer Ag | Verfahren zur Herstellung von Polycarbonaten |
| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5434178A (en) * | 1993-11-30 | 1995-07-18 | G.D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| US5466823A (en) | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| US5908852A (en) * | 1994-11-14 | 1999-06-01 | G. D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| US5633272A (en) | 1995-02-13 | 1997-05-27 | Talley; John J. | Substituted isoxazoles for the treatment of inflammation |
| EP1109551A4 (de) * | 1998-08-21 | 2004-10-20 | Competitive Tech Inc | 4-amino-3-mescapto-1,2,4-triazole |
| EP1099695A1 (de) * | 1999-11-09 | 2001-05-16 | Laboratoire Theramex S.A. | 5-Aryl-1H-1,2,4-triazolverbindungen als Cyclooxygenase-2 Inhibitoren und diese enthaltende pharmazeutische Zusammensetzungen |
| US6451820B1 (en) * | 2000-03-23 | 2002-09-17 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenly)triazoles and their use as anti-inflammatory agents |
| DE10123586A1 (de) * | 2001-05-08 | 2002-11-28 | Schering Ag | 3,5-Diamino-1,2,4-triazole als Kinase Inhibitoren |
-
2002
- 2002-11-21 KR KR10-2002-0072688A patent/KR100470075B1/ko not_active Expired - Fee Related
-
2003
- 2003-07-29 CN CNB038256940A patent/CN100355738C/zh not_active Expired - Fee Related
- 2003-07-29 DE DE60335960T patent/DE60335960D1/de not_active Expired - Lifetime
- 2003-07-29 JP JP2004553243A patent/JP4348300B2/ja not_active Expired - Fee Related
- 2003-07-29 EP EP03811548A patent/EP1567508B1/de not_active Expired - Lifetime
- 2003-07-29 AT AT03811548T patent/ATE497497T1/de not_active IP Right Cessation
- 2003-07-29 ES ES03811548T patent/ES2357834T3/es not_active Expired - Lifetime
- 2003-07-29 AU AU2003256091A patent/AU2003256091A1/en not_active Abandoned
- 2003-07-29 WO PCT/KR2003/001514 patent/WO2004046121A1/en not_active Ceased
- 2003-07-31 US US10/631,594 patent/US6849652B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1567508A4 (de) | 2008-12-10 |
| CN1717397A (zh) | 2006-01-04 |
| WO2004046121A1 (en) | 2004-06-03 |
| CN100355738C (zh) | 2007-12-19 |
| JP4348300B2 (ja) | 2009-10-21 |
| EP1567508B1 (de) | 2011-02-02 |
| KR100470075B1 (ko) | 2005-02-05 |
| US6849652B1 (en) | 2005-02-01 |
| DE60335960D1 (de) | 2011-03-17 |
| AU2003256091A1 (en) | 2004-06-15 |
| JP2006514631A (ja) | 2006-05-11 |
| ES2357834T3 (es) | 2011-05-03 |
| EP1567508A1 (de) | 2005-08-31 |
| KR20040044614A (ko) | 2004-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |