ATE498011T1 - Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen - Google Patents

Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen

Info

Publication number
ATE498011T1
ATE498011T1 AT01928006T AT01928006T ATE498011T1 AT E498011 T1 ATE498011 T1 AT E498011T1 AT 01928006 T AT01928006 T AT 01928006T AT 01928006 T AT01928006 T AT 01928006T AT E498011 T1 ATE498011 T1 AT E498011T1
Authority
AT
Austria
Prior art keywords
embryonal stem
modified
specific gene
cells
stem cells
Prior art date
Application number
AT01928006T
Other languages
English (en)
Inventor
Herve Acloque
Anne-Marie Birot
Valerie Risson
Bertrand Pain
Jacques Samarut
Original Assignee
Agronomique Inst Nat Rech
Centre Nat Rech Scient
Ecole Norm Superieure Lyon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agronomique Inst Nat Rech, Centre Nat Rech Scient, Ecole Norm Superieure Lyon filed Critical Agronomique Inst Nat Rech
Application granted granted Critical
Publication of ATE498011T1 publication Critical patent/ATE498011T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01928006T 2000-05-11 2001-04-19 Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen ATE498011T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0006029A FR2808803B1 (fr) 2000-05-11 2000-05-11 Cellules es modifiees et gene specifique de cellules es
PCT/FR2001/001207 WO2001085938A1 (fr) 2000-05-11 2001-04-19 Cellules es modifiees et gene specifique de cellules es

Publications (1)

Publication Number Publication Date
ATE498011T1 true ATE498011T1 (de) 2011-02-15

Family

ID=8850125

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01928006T ATE498011T1 (de) 2000-05-11 2001-04-19 Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen

Country Status (14)

Country Link
US (2) US20040072169A1 (de)
EP (1) EP1280898B1 (de)
JP (1) JP2004515212A (de)
AT (1) ATE498011T1 (de)
AU (2) AU5488501A (de)
BR (1) BR0110764A (de)
CA (1) CA2408732A1 (de)
DE (1) DE60144015D1 (de)
DK (1) DK1280898T3 (de)
ES (1) ES2358731T3 (de)
FR (1) FR2808803B1 (de)
NO (1) NO331814B1 (de)
NZ (1) NZ522547A (de)
WO (1) WO2001085938A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2808803B1 (fr) * 2000-05-11 2004-12-10 Agronomique Inst Nat Rech Cellules es modifiees et gene specifique de cellules es
ES2633306T3 (es) * 2001-05-31 2017-09-20 Shinya Yamanaka Genes con expresión específica de células ES
ES2359214T5 (es) 2005-11-01 2014-10-08 Novartis Vaccines And Diagnostics Gmbh Vacunas virales derivadas de células con niveles reducidos de ADN celular residual por tratamiento con beta-propiolactona
CN102755645A (zh) 2005-11-04 2012-10-31 诺华疫苗和诊断有限公司 佐剂配制的包含细胞因子诱导剂的流感疫苗
BRPI0618254A2 (pt) 2005-11-04 2011-08-23 Novartis Vaccines & Diagnostic emulsões com agente tensoativo de fase aquosa livre para fornecer adjuvante às vacinas contra influenza dividido
PL1951299T3 (pl) 2005-11-04 2012-07-31 Novartis Ag Szczepionki przeciw grypie zawierające kombinacje adiuwantów cząsteczkowych i czynników wzmacniających immunogenność
US20090304742A1 (en) 2005-11-04 2009-12-10 Novartis Vaccines And Diagnostics Srl Influenza vaccines with reduced amount of emulsion adjuvant
PL1945252T3 (pl) 2005-11-04 2013-11-29 Seqirus Uk Ltd Szczepionki zawierające oczyszczone antygeny powierzchniowe otrzymane z wirusów grypy hodowanych w hodowli komórkowej i skwalen jako adiuwant
KR20080089663A (ko) 2006-01-27 2008-10-07 노바티스 백신즈 앤드 다이아그노스틱스 게엠베하 운트 콤파니 카게 적혈구응집소 및 기질 단백질을 함유한 인플루엔자 백신
FR2898909A1 (fr) 2006-03-24 2007-09-28 Agronomique Inst Nat Rech Combinaison de marqueurs de cellules aviaires
JP2009534303A (ja) 2006-03-24 2009-09-24 ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー 冷蔵しないインフルエンザワクチンの保存
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
CN101553252A (zh) 2006-12-06 2009-10-07 诺华有限公司 包含来自于四株流感病毒的抗原的疫苗
HRP20120790T1 (hr) 2007-06-27 2013-01-31 Novartis Ag Cjepiva protiv influence sa niskom koliäśinom aditiva
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
ES2535101T3 (es) 2008-03-18 2015-05-05 Novartis Ag Mejoras en la preparación de antígenos en vacuna de virus de la gripe
WO2010079081A1 (en) 2009-01-07 2010-07-15 Glaxosmithkline Biologicals S.A. Methods for recovering a virus or a viral antigen produced by cell culture
EP2393922A1 (de) 2009-02-06 2011-12-14 GlaxoSmithKline Biologicals S.A. Aufreinigung von virus oder viralen antigenen mittels dichtegradienten-ultrazentrifugation
EP2396032B1 (de) 2009-02-10 2016-09-28 Seqirus UK Limited Influenza-impfstoffe mit reduzierten squalen-mengen
WO2010092477A1 (en) 2009-02-10 2010-08-19 Novartis Ag Influenza vaccines with increased amounts of h3 antigen
WO2010092476A1 (en) 2009-02-10 2010-08-19 Novartis Ag Influenza vaccine regimens for pandemic-associated strains
CA2763816A1 (en) 2009-04-27 2010-11-04 Novartis Ag Adjuvanted vaccines for protecting against influenza
CA2773637A1 (en) 2009-09-10 2011-03-17 Novartis Ag Combination vaccines against respiratory tract diseases
US20120309056A1 (en) 2010-02-04 2012-12-06 Leon Arnaud Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
JP2013521771A (ja) 2010-03-08 2013-06-13 ノバルティス アーゲー 細胞内病原体について試験する方法
CA2797059A1 (en) 2010-05-03 2011-11-10 Glaxosmithkline Biologicals S.A. Novel method
BR112012028146A2 (pt) 2010-05-06 2015-09-15 Novartis Ag compostos de peróxido orgânico para inativação de microorganismos
JP5876036B2 (ja) 2010-05-21 2016-03-02 ノバルティス アーゲー インフルエンザウイルス再集合方法
US20130243841A1 (en) 2010-06-01 2013-09-19 Novartis Ag Concentration of vaccine antigens with lyophilization
DK2575872T3 (da) 2010-06-01 2020-10-19 Seqirus Uk Ltd Koncentrering af influenzavaccineantigener uden frysetørring
US9517205B2 (en) 2010-08-20 2016-12-13 Seqirus UK Limited Soluble needle arrays for delivery of influenza vaccines
JP2014518080A (ja) 2011-06-27 2014-07-28 バルネバ 細胞のスクリーニング方法
GB201216121D0 (en) 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
EP2768528A1 (de) 2011-10-20 2014-08-27 Novartis AG Adjuvierte influenza-b-viren-impfstoffe für kinder
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
WO2015028546A1 (en) 2013-08-30 2015-03-05 Glaxosmithkline Biologicals S.A. Large scale production of viruses in cell culture
US20170369854A1 (en) 2014-12-16 2017-12-28 Glaxosmithkline Biologicals Sa A method for a large scale virus purification
RU2745567C2 (ru) 2014-12-17 2021-03-29 Фундасион Пара Ла Инвестигасион Медика Апликада Конструкции нуклеиновой кислоты и векторы для генотерапии для применения для лечения болезни вильсона и других состояний
US11118238B2 (en) 2014-12-17 2021-09-14 Fundación Para La Investigación Mèdica Aplicada Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson's disease and other conditions
AU2016281904B2 (en) 2015-06-26 2022-08-11 Seqirus UK Limited Antigenically matched influenza vaccines
WO2017005880A1 (en) 2015-07-07 2017-01-12 Seqirus UK Limited Influenza potency assays
SG11202004926WA (en) 2017-12-01 2020-06-29 Encoded Therapeutics Inc Engineered dna binding proteins
US20210180084A1 (en) 2018-05-14 2021-06-17 Vivet Therapeutics Gene therapy vectors comprising s/mar sequences
BR112021006881A2 (pt) 2018-10-12 2021-07-13 Vivet Therapeutics transgene otimizado por códon para o tratamento de colestase intra-hepática familiar progressiva tipo 3 (pfic3)
WO2020102723A1 (en) 2018-11-16 2020-05-22 Encoded Therapeutics, Inc. Compositions and methods for treating wilson's disease
BR112021024055A2 (pt) 2019-05-29 2022-02-08 Encoded Therapeutics Inc Composições e métodos para a regulação seletiva de gene
WO2021001377A1 (en) 2019-07-02 2021-01-07 Fundacion Para La Investigacion Medica Aplicada cPLA2e INDUCING AGENTS AND USES THEREOF
US12576146B2 (en) 2019-11-18 2026-03-17 Seqirus UK Limited Method for producing reassortant influenza viruses
CA3181024A1 (en) 2020-08-06 2022-02-10 Fundacion Para La Investigacion Medica Aplicada Viral particles for use in treating tauopathies such as alzheimer's diseases by gene therapy
US20230265456A1 (en) 2020-08-10 2023-08-24 Fundacion Para La Investigacion Medica Aplicada Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis
CN116390935A (zh) 2020-10-09 2023-07-04 Ucb生物制药有限责任公司 核酸构建体、病毒载体和病毒颗粒
MX2024005171A (es) 2021-10-28 2024-05-13 UCB Biopharma SRL Constructos de acido nucleico, vectores viricos y particulas viricas.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309822B1 (en) * 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
EP1117765A2 (de) * 1998-08-31 2001-07-25 New York University Stammzellen mit einem fgf rezeptor auf der zelloberfläche
FR2808803B1 (fr) * 2000-05-11 2004-12-10 Agronomique Inst Nat Rech Cellules es modifiees et gene specifique de cellules es

Also Published As

Publication number Publication date
US20040072169A1 (en) 2004-04-15
EP1280898B1 (de) 2011-02-09
FR2808803B1 (fr) 2004-12-10
DK1280898T3 (da) 2011-05-16
NO20025402L (no) 2003-01-08
AU5488501A (en) 2001-11-20
NO331814B1 (no) 2012-04-10
BR0110764A (pt) 2003-05-06
ES2358731T3 (es) 2011-05-13
DE60144015D1 (de) 2011-03-24
FR2808803A1 (fr) 2001-11-16
JP2004515212A (ja) 2004-05-27
AU2001254885B2 (en) 2006-08-10
US20090151013A1 (en) 2009-06-11
EP1280898A1 (de) 2003-02-05
WO2001085938A1 (fr) 2001-11-15
CA2408732A1 (fr) 2001-11-15
NO20025402D0 (no) 2002-11-11
NZ522547A (en) 2006-02-24

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