ATE498622T1 - Prolinamidtetrazolderivate als nk3- rezeptorantagonisten - Google Patents

Prolinamidtetrazolderivate als nk3- rezeptorantagonisten

Info

Publication number: ATE498622T1
Authority: AT; Austria
Prior art keywords: receptor antagonists; prolinamide; tetrazole derivatives; disorders; adhd
Prior art date: 2007-06-07

Application number

AT08760179T

Other languages

English (en)

Inventor

Bo Han

Henner Knust

Matthias Nettekoven

Hasane Ratni

Xihan Wu

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-07

Filing date

2008-05-29

Publication date

2011-03-15

2008-05-29 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2011-03-15 Application granted granted Critical

2011-03-15 Publication of ATE498622T1 publication Critical patent/ATE498622T1/de

Links

239000002464 receptor antagonist Substances 0.000 title abstract 2
229940044551 receptor antagonist Drugs 0.000 title abstract 2
102000002003 Neurokinin-3 Receptors Human genes 0.000 title 1
108010040716 Neurokinin-3 Receptors Proteins 0.000 title 1
-1 PROLINAMIDE TETRAZOLE Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
208000020925 Bipolar disease Diseases 0.000 abstract 1
101001125071 Homo sapiens Neuromedin-K receptor Proteins 0.000 abstract 1
102100029409 Neuromedin-K receptor Human genes 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
208000018737 Parkinson disease Diseases 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
201000000980 schizophrenia Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT08760179T 2007-06-07 2008-05-29 Prolinamidtetrazolderivate als nk3- rezeptorantagonisten ATE498622T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07109783		2007-06-07
PCT/EP2008/056587 WO2008148688A1 (en)	2007-06-07	2008-05-29	Prolinamide-tetrazole derivatives as nk3 receptor antagonists

Publications (1)

Publication Number	Publication Date
ATE498622T1 true ATE498622T1 (de)	2011-03-15

Family

ID=39768738

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08760179T ATE498622T1 (de)	2007-06-07	2008-05-29	Prolinamidtetrazolderivate als nk3- rezeptorantagonisten

Country Status (14)

Country	Link
US (1)	US7501422B2 (de)
EP (1)	EP2155729B1 (de)
JP (1)	JP2010529068A (de)
KR (1)	KR101163294B1 (de)
CN (1)	CN101679385A (de)
AT (1)	ATE498622T1 (de)
AU (1)	AU2008258664B2 (de)
BR (1)	BRPI0812253A2 (de)
CA (1)	CA2690292A1 (de)
DE (1)	DE602008005014D1 (de)
ES (1)	ES2359598T3 (de)
IL (1)	IL202282A0 (de)
MX (1)	MX2009013116A (de)
WO (1)	WO2008148688A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2023042914A1 (en) *	2021-09-17	2023-03-23	Otsuka Pharmaceutical Co., Ltd.	Pyrrolidine compounds as histone deacetylase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040034019A1 (en)	2002-08-08	2004-02-19	Ronald Tomlinson	Piperazine and piperidine derivatives

2008
- 2008-05-29 CA CA2690292A patent/CA2690292A1/en not_active Abandoned
- 2008-05-29 DE DE602008005014T patent/DE602008005014D1/de active Active
- 2008-05-29 CN CN200880018987A patent/CN101679385A/zh active Pending
- 2008-05-29 MX MX2009013116A patent/MX2009013116A/es active IP Right Grant
- 2008-05-29 KR KR1020107000225A patent/KR101163294B1/ko not_active Expired - Fee Related
- 2008-05-29 AU AU2008258664A patent/AU2008258664B2/en not_active Ceased
- 2008-05-29 JP JP2010510746A patent/JP2010529068A/ja not_active Ceased
- 2008-05-29 ES ES08760179T patent/ES2359598T3/es active Active
- 2008-05-29 BR BRPI0812253-9A2A patent/BRPI0812253A2/pt not_active IP Right Cessation
- 2008-05-29 EP EP08760179A patent/EP2155729B1/de not_active Not-in-force
- 2008-05-29 WO PCT/EP2008/056587 patent/WO2008148688A1/en not_active Ceased
- 2008-05-29 AT AT08760179T patent/ATE498622T1/de active
- 2008-05-30 US US12/129,720 patent/US7501422B2/en not_active Expired - Fee Related
2009
- 2009-11-23 IL IL202282A patent/IL202282A0/en unknown

Also Published As

Publication number	Publication date
CA2690292A1 (en)	2008-12-11
US20080306089A1 (en)	2008-12-11
KR101163294B1 (ko)	2012-07-05
EP2155729A1 (de)	2010-02-24
EP2155729B1 (de)	2011-02-16
MX2009013116A (es)	2010-01-15
JP2010529068A (ja)	2010-08-26
AU2008258664A8 (en)	2010-01-14
ES2359598T3 (es)	2011-05-25
BRPI0812253A2 (pt)	2014-12-23
DE602008005014D1 (de)	2011-03-31
IL202282A0 (en)	2010-06-16
WO2008148688A1 (en)	2008-12-11
CN101679385A (zh)	2010-03-24
AU2008258664B2 (en)	2012-07-05
US7501422B2 (en)	2009-03-10
AU2008258664A1 (en)	2008-12-11
KR20100020026A (ko)	2010-02-19

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Legal Events

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2011-09-15

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