ATE499069T1 - LIQUID POLYMER SOLUTION FOR THE CONTROLLED RELEASE OF BIOACTIVE SUBSTANCES - Google Patents

LIQUID POLYMER SOLUTION FOR THE CONTROLLED RELEASE OF BIOACTIVE SUBSTANCES

Info

Publication number
ATE499069T1
ATE499069T1 AT04076699T AT04076699T ATE499069T1 AT E499069 T1 ATE499069 T1 AT E499069T1 AT 04076699 T AT04076699 T AT 04076699T AT 04076699 T AT04076699 T AT 04076699T AT E499069 T1 ATE499069 T1 AT E499069T1
Authority
AT
Austria
Prior art keywords
controlled release
polymer solution
liquid polymer
bioactive substances
casing
Prior art date
Application number
AT04076699T
Other languages
German (de)
Inventor
Rey T Chern
Joel R Zingerman
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE499069T1 publication Critical patent/ATE499069T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

1. Technical Result Preparing liquid composition covered with casing and/or forming incapsulated liquid in the casing. 2. Essence A composition comprises hydrophobic bioactive substance, lactide and glycolide copolymer and a mixture of hydrophilic and lipophilic solvents. 3. Field of Application Medicine.
AT04076699T 1998-03-19 1999-03-18 LIQUID POLYMER SOLUTION FOR THE CONTROLLED RELEASE OF BIOACTIVE SUBSTANCES ATE499069T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7957498P 1998-03-19 1998-03-19
GBGB9815801.7A GB9815801D0 (en) 1998-07-21 1998-07-21 Liquid polymeric compositions for controlled released bioactive substances

Publications (1)

Publication Number Publication Date
ATE499069T1 true ATE499069T1 (en) 2011-03-15

Family

ID=10835852

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04076699T ATE499069T1 (en) 1998-03-19 1999-03-18 LIQUID POLYMER SOLUTION FOR THE CONTROLLED RELEASE OF BIOACTIVE SUBSTANCES

Country Status (10)

Country Link
JP (1) JP4829405B2 (en)
AT (1) ATE499069T1 (en)
DE (1) DE69943225D1 (en)
DK (1) DK1484033T3 (en)
GB (1) GB9815801D0 (en)
GE (1) GEP20033012B (en)
PT (1) PT1484033E (en)
RS (1) RS49840B (en)
SI (1) SI1484033T1 (en)
UA (1) UA53788C2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8362086B2 (en) * 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
CN104168886A (en) * 2012-03-13 2014-11-26 拜耳新西兰有限公司 Long acting compositions
BR112016005589B8 (en) * 2013-09-16 2023-04-18 Merck Sharp & Dohme LIQUID PHARMACEUTICAL COMPOSITION, AND USE THEREOF
KR102101969B1 (en) * 2017-09-06 2020-04-22 (주)인벤티지랩 Microparticles containing moxidectin and method for manufacturing same

Also Published As

Publication number Publication date
GEP20033012B (en) 2003-07-25
JP2002506797A (en) 2002-03-05
JP4829405B2 (en) 2011-12-07
DK1484033T3 (en) 2011-06-14
YU54100A (en) 2002-11-15
SI1484033T1 (en) 2011-06-30
DE69943225D1 (en) 2011-04-07
GB9815801D0 (en) 1998-09-16
RS49840B (en) 2008-08-07
UA53788C2 (en) 2003-02-17
PT1484033E (en) 2011-04-21

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