ATE500561T1 - Proteinveränderung - Google Patents

Proteinveränderung

Info

Publication number
ATE500561T1
ATE500561T1 AT99970666T AT99970666T ATE500561T1 AT E500561 T1 ATE500561 T1 AT E500561T1 AT 99970666 T AT99970666 T AT 99970666T AT 99970666 T AT99970666 T AT 99970666T AT E500561 T1 ATE500561 T1 AT E500561T1
Authority
AT
Austria
Prior art keywords
protein
orientation
location
space
framework
Prior art date
Application number
AT99970666T
Other languages
English (en)
Inventor
Mark Smythe
Michael Dooley
Peter Andrews
Original Assignee
Univ Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Queensland filed Critical Univ Queensland
Application granted granted Critical
Publication of ATE500561T1 publication Critical patent/ATE500561T1/de

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/20—Protein or domain folding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Saccharide Compounds (AREA)
AT99970666T 1998-10-21 1999-10-21 Proteinveränderung ATE500561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPP6606A AUPP660698A0 (en) 1998-10-21 1998-10-21 A method of protein engineering
PCT/AU1999/000914 WO2000023474A1 (en) 1998-10-21 1999-10-21 Protein engineering

Publications (1)

Publication Number Publication Date
ATE500561T1 true ATE500561T1 (de) 2011-03-15

Family

ID=3810827

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99970666T ATE500561T1 (de) 1998-10-21 1999-10-21 Proteinveränderung

Country Status (8)

Country Link
US (2) US7092825B1 (de)
EP (1) EP1123316B1 (de)
JP (1) JP4633930B2 (de)
AT (1) ATE500561T1 (de)
AU (1) AUPP660698A0 (de)
CA (1) CA2347917C (de)
DE (1) DE69943242D1 (de)
WO (1) WO2000023474A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP660698A0 (en) * 1998-10-21 1998-11-12 University Of Queensland, The A method of protein engineering
WO2002005133A1 (en) * 2000-07-07 2002-01-17 Kent Ridge Digital Labs A method and apparatus for searching a database containing biological information
FR2827046B1 (fr) * 2001-07-06 2004-01-23 Commissariat Energie Atomique Procede de criblage de molecules aptes a se lier a la proteine gp120 du virus de l'immunodeficience
AU2003202324B2 (en) * 2002-02-08 2008-05-08 The University Of Queensland Common protein surface shapes and uses therefor
AUPS039702A0 (en) * 2002-02-08 2002-03-07 University Of Queensland, The Common protein surface shapes and uses therefor
US20060020396A1 (en) * 2002-09-09 2006-01-26 Rene Gantier Rational directed protein evolution using two-dimensional rational mutagenesis scanning
DE60332358D1 (de) * 2002-09-09 2010-06-10 Hanall Pharmaceutical Co Ltd Protease-resistente modifizierte interferon alpha polypeptide
JP5170630B2 (ja) * 2007-12-19 2013-03-27 独立行政法人産業技術総合研究所 タンパク質機能識別装置
US9273093B2 (en) 2012-10-11 2016-03-01 Protagonist Therapeutics, Inc. α4β7 peptide dimer antagonists
DK2923291T3 (da) * 2012-11-26 2020-08-03 Innophore Gmbh Fastlæggelse af nye enzymatiske funktionaliteter under anvendelse af tredimensionelle punktskyer, der repræsenterer fysisk-kemiske egenskaber hos proteinkaviteter
EP4091624A1 (de) 2013-03-15 2022-11-23 Protagonist Therapeutics, Inc. Hepcidin-analoga und verwendungen davon
HRP20211448T1 (hr) 2014-05-16 2021-12-24 Protagonist Therapeutics, Inc. Alfa4beta7 integrin tioeter peptidni antagonisti
CN107206254B (zh) 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
WO2016054411A1 (en) 2014-10-01 2016-04-07 Protagonist Therapeutics, Inc. NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS
US10301371B2 (en) 2014-10-01 2019-05-28 Protagonist Therapeutics, Inc. Cyclic monomer and dimer peptides having integrin antagonist activity
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
CA3017926C (en) 2016-03-23 2023-10-10 Protagonist Therapeutics, Inc. Methods for synthesizing .alpha.4.beta.7 peptide antagonists
EP3681900A4 (de) 2017-09-11 2021-09-08 Protagonist Therapeutics, Inc. Opioidagonistpeptide und verwendungen davon
CA3089868A1 (en) 2018-02-08 2019-08-15 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
WO2020014646A1 (en) 2018-07-12 2020-01-16 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
JP7112312B2 (ja) * 2018-10-26 2022-08-03 富士通株式会社 化合物探索装置、化合物探索方法、及び化合物探索プログラム
JP7579812B2 (ja) * 2019-05-31 2024-11-08 アイバイオ， インク． メソスケールペプチドを操作するための機械学習ベースの装置およびそのための方法およびシステム
JP7534382B2 (ja) 2019-07-10 2024-08-14 プロタゴニスト セラピューティクス， インコーポレイテッド インターロイキン－２３受容体のペプチド阻害剤及び炎症性疾患を治療するためのその使用
CA3167751A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
AU2021209086A1 (en) 2020-01-15 2022-08-04 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
JP7397239B2 (ja) 2020-11-20 2023-12-12 ヤンセン ファーマシューティカ エヌ．ベー． インターロイキン－２３受容体のペプチド阻害剤の組成物
EP4370146A4 (de) 2021-07-14 2025-05-21 Janssen Biotech, Inc. Lipidierte peptidinhibitoren des interleukin-23-rezeptors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704692A (en) * 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US4853871A (en) * 1987-04-06 1989-08-01 Genex Corporation Computer-based method for designing stablized proteins
WO1993001484A1 (en) * 1991-07-11 1993-01-21 The Regents Of The University Of California A method to identify protein sequences that fold into a known three-dimensional structure
JPH0673088A (ja) * 1992-08-28 1994-03-15 Fujitsu Ltd Ｓｓ結合の表示方法
TW263437B (de) * 1992-09-24 1995-11-21 Takeda Pharm Industry Co Ltd
AU6136694A (en) 1993-02-12 1994-08-29 Repligen Corporation Methods for generating broadly neutralizing anti-hiv antibodies and antigens capable of eliciting same
JP3867863B2 (ja) * 1993-07-13 2007-01-17 富士通株式会社 立体構造処理装置
US5752019A (en) * 1995-12-22 1998-05-12 International Business Machines Corporation System and method for confirmationally-flexible molecular identification
US5835382A (en) * 1996-04-26 1998-11-10 The Scripps Research Institute Small molecule mimetics of erythropoietin
US5878373A (en) * 1996-12-06 1999-03-02 Regents Of The University Of California System and method for determining three-dimensional structure of protein sequences
EP1008572A1 (de) * 1997-07-03 2000-06-14 ITAI, Akiko Verfahren zum ableiten von proteinfunktionen unter verwendung einer ligand-datenbank
EP1028317A4 (de) * 1997-10-02 2002-10-02 Akiko Itai Verfahren zum beeinflussen der dreidimensionalen struktur eines proteins
AU1283199A (en) * 1997-10-29 1999-05-17 Rutgers, The State University Of New Jersey Linking gene sequence to gene function by three-dimensional (3d) protein structure determination
JPH11232291A (ja) * 1998-02-16 1999-08-27 Seibutsu Bunshi Kogaku Kenkyusho:Kk 蛋白質立体構造データベース検索方法
AUPP660698A0 (en) * 1998-10-21 1998-11-12 University Of Queensland, The A method of protein engineering

Also Published As

Publication number Publication date
AUPP660698A0 (en) 1998-11-12
CA2347917C (en) 2018-08-21
WO2000023474A1 (en) 2000-04-27
DE69943242D1 (de) 2011-04-14
JP2002527845A (ja) 2002-08-27
EP1123316A1 (de) 2001-08-16
US20070016380A1 (en) 2007-01-18
EP1123316B1 (de) 2011-03-02
EP1123316A4 (de) 2007-10-17
JP4633930B2 (ja) 2011-02-16
US7092825B1 (en) 2006-08-15
CA2347917A1 (en) 2000-04-27

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