ATE500561T1 - Proteinveränderung - Google Patents

Proteinveränderung

Info

Publication number
ATE500561T1
ATE500561T1 AT99970666T AT99970666T ATE500561T1 AT E500561 T1 ATE500561 T1 AT E500561T1 AT 99970666 T AT99970666 T AT 99970666T AT 99970666 T AT99970666 T AT 99970666T AT E500561 T1 ATE500561 T1 AT E500561T1
Authority
AT
Austria
Prior art keywords
protein
orientation
location
space
framework
Prior art date
Application number
AT99970666T
Other languages
English (en)
Inventor
Mark Smythe
Michael Dooley
Peter Andrews
Original Assignee
Univ Queensland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Queensland filed Critical Univ Queensland
Application granted granted Critical
Publication of ATE500561T1 publication Critical patent/ATE500561T1/de

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/20—Protein or domain folding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
AT99970666T 1998-10-21 1999-10-21 Proteinveränderung ATE500561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPP6606A AUPP660698A0 (en) 1998-10-21 1998-10-21 A method of protein engineering
PCT/AU1999/000914 WO2000023474A1 (en) 1998-10-21 1999-10-21 Protein engineering

Publications (1)

Publication Number Publication Date
ATE500561T1 true ATE500561T1 (de) 2011-03-15

Family

ID=3810827

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99970666T ATE500561T1 (de) 1998-10-21 1999-10-21 Proteinveränderung

Country Status (8)

Country Link
US (2) US7092825B1 (de)
EP (1) EP1123316B1 (de)
JP (1) JP4633930B2 (de)
AT (1) ATE500561T1 (de)
AU (1) AUPP660698A0 (de)
CA (1) CA2347917C (de)
DE (1) DE69943242D1 (de)
WO (1) WO2000023474A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP660698A0 (en) * 1998-10-21 1998-11-12 University Of Queensland, The A method of protein engineering
WO2002005133A1 (en) * 2000-07-07 2002-01-17 Kent Ridge Digital Labs A method and apparatus for searching a database containing biological information
FR2827046B1 (fr) * 2001-07-06 2004-01-23 Commissariat Energie Atomique Procede de criblage de molecules aptes a se lier a la proteine gp120 du virus de l'immunodeficience
AU2003202324B2 (en) * 2002-02-08 2008-05-08 The University Of Queensland Common protein surface shapes and uses therefor
AUPS039702A0 (en) * 2002-02-08 2002-03-07 University Of Queensland, The Common protein surface shapes and uses therefor
US20060020396A1 (en) * 2002-09-09 2006-01-26 Rene Gantier Rational directed protein evolution using two-dimensional rational mutagenesis scanning
WO2004022593A2 (en) * 2002-09-09 2004-03-18 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
JP5170630B2 (ja) * 2007-12-19 2013-03-27 独立行政法人産業技術総合研究所 タンパク質機能識別装置
US9273093B2 (en) 2012-10-11 2016-03-01 Protagonist Therapeutics, Inc. α4β7 peptide dimer antagonists
SI2923291T1 (sl) * 2012-11-26 2020-09-30 Innophore Gmbh Ugotavljanje novih encimskih funkcionalnosti z uporabo oblakov tridimenzionalnih točk, ki predstavljajo fizikalno-kemijske lastnosti votlin znotraj proteina
EP4091624A1 (de) 2013-03-15 2022-11-23 Protagonist Therapeutics, Inc. Hepcidin-analoga und verwendungen davon
CA2949215C (en) 2014-05-16 2023-03-14 Protagonist Therapeutics, Inc. .alpha.4.beta.7 integrin thioether peptide antagonists
SG10201810154WA (en) 2014-07-17 2018-12-28 Protagonist Therapeutics Inc Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
WO2016054445A1 (en) 2014-10-01 2016-04-07 Protagonist Therapeutics, Inc. Novel cyclic monomer and dimer peptides having integrin antagonist activity
JP2017535527A (ja) 2014-10-01 2017-11-30 プロタゴニスト セラピューティクス， インコーポレイテッド 新規のα４β７ペプチド単量体及び二量体拮抗薬
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
CA3009834A1 (en) 2015-12-30 2017-07-06 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
CA3017926C (en) 2016-03-23 2023-10-10 Protagonist Therapeutics, Inc. Methods for synthesizing .alpha.4.beta.7 peptide antagonists
WO2018022937A1 (en) 2016-07-27 2018-02-01 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 and their use to treat inflammatory diseases
EP3681900A4 (de) 2017-09-11 2021-09-08 Protagonist Therapeutics, Inc. Opioidagonistpeptide und verwendungen davon
WO2019157268A1 (en) 2018-02-08 2019-08-15 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
CA3104418A1 (en) 2018-07-12 2020-01-16 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
JP7112312B2 (ja) * 2018-10-26 2022-08-03 富士通株式会社 化合物探索装置、化合物探索方法、及び化合物探索プログラム
CA3142339A1 (en) 2019-05-31 2020-12-03 Rubryc Therapeutics, Inc. Machine learning-based apparatus for engineering meso-scale peptides and methods and system for the same
AU2020311395A1 (en) 2019-07-10 2022-02-03 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
MX2022008740A (es) 2020-01-15 2022-09-23 Janssen Biotech Inc Peptidos inhibidores del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.
SMT202500254T1 (it) 2020-01-15 2025-09-12 Janssen Biotech Inc Inibitori peptidici del recettore dell'interleuchina-23 e loro uso per trattare malattie infiammatorie
AU2021383828A1 (en) 2020-11-20 2023-07-06 Janssen Pharmaceutica Nv Compositions of peptide inhibitors of interleukin-23 receptor
KR20240034224A (ko) 2021-07-14 2024-03-13 얀센 바이오테크 인코포레이티드 인터류킨-23 수용체의 지질화된 펩티드 억제제

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704692A (en) * 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US4853871A (en) * 1987-04-06 1989-08-01 Genex Corporation Computer-based method for designing stablized proteins
WO1993001484A1 (en) * 1991-07-11 1993-01-21 The Regents Of The University Of California A method to identify protein sequences that fold into a known three-dimensional structure
JPH0673088A (ja) * 1992-08-28 1994-03-15 Fujitsu Ltd Ｓｓ結合の表示方法
TW263437B (de) * 1992-09-24 1995-11-21 Takeda Pharm Industry Co Ltd
WO1994018232A1 (en) 1993-02-12 1994-08-18 Repligen Corporation Methods for generating broadly neutralizing anti-hiv antibodies and antigens capable of eliciting same
JP3867863B2 (ja) * 1993-07-13 2007-01-17 富士通株式会社 立体構造処理装置
US5752019A (en) 1995-12-22 1998-05-12 International Business Machines Corporation System and method for confirmationally-flexible molecular identification
US5835382A (en) * 1996-04-26 1998-11-10 The Scripps Research Institute Small molecule mimetics of erythropoietin
US5878373A (en) * 1996-12-06 1999-03-02 Regents Of The University Of California System and method for determining three-dimensional structure of protein sequences
EP1008572A1 (de) * 1997-07-03 2000-06-14 ITAI, Akiko Verfahren zum ableiten von proteinfunktionen unter verwendung einer ligand-datenbank
WO1999018440A1 (fr) * 1997-10-02 1999-04-15 Akiko Itai Procede relatif a l'inference d'une structure de proteine tridimensionnelle
AU1283199A (en) * 1997-10-29 1999-05-17 Rutgers, The State University Of New Jersey Linking gene sequence to gene function by three-dimensional (3d) protein structure determination
JPH11232291A (ja) * 1998-02-16 1999-08-27 Seibutsu Bunshi Kogaku Kenkyusho:Kk 蛋白質立体構造データベース検索方法
AUPP660698A0 (en) * 1998-10-21 1998-11-12 University Of Queensland, The A method of protein engineering

Also Published As

Publication number Publication date
US20070016380A1 (en) 2007-01-18
JP4633930B2 (ja) 2011-02-16
EP1123316B1 (de) 2011-03-02
JP2002527845A (ja) 2002-08-27
EP1123316A4 (de) 2007-10-17
WO2000023474A1 (en) 2000-04-27
AUPP660698A0 (en) 1998-11-12
US7092825B1 (en) 2006-08-15
CA2347917A1 (en) 2000-04-27
CA2347917C (en) 2018-08-21
EP1123316A1 (de) 2001-08-16
DE69943242D1 (de) 2011-04-14

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