ATE500836T1 - Adrenomedullin und adrenomedullin-bindungsprotein zur ischämie/reperfusionsbehandlung - Google Patents
Adrenomedullin und adrenomedullin-bindungsprotein zur ischämie/reperfusionsbehandlungInfo
- Publication number
- ATE500836T1 ATE500836T1 AT05732325T AT05732325T ATE500836T1 AT E500836 T1 ATE500836 T1 AT E500836T1 AT 05732325 T AT05732325 T AT 05732325T AT 05732325 T AT05732325 T AT 05732325T AT E500836 T1 ATE500836 T1 AT E500836T1
- Authority
- AT
- Austria
- Prior art keywords
- adrenomedullin
- ischemia
- binding protein
- mammal
- reperfusion treatment
- Prior art date
Links
- 102000004379 Adrenomedullin Human genes 0.000 title abstract 4
- 101800004616 Adrenomedullin Proteins 0.000 title abstract 4
- ULCUCJFASIJEOE-NPECTJMMSA-N adrenomedullin Chemical compound C([C@@H](C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)NCC(=O)N[C@@H]1C(N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)[C@@H](C)O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 ULCUCJFASIJEOE-NPECTJMMSA-N 0.000 title abstract 4
- 208000028867 ischemia Diseases 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000010410 reperfusion Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 4
- 206010063837 Reperfusion injury Diseases 0.000 abstract 2
- 208000027418 Wounds and injury Diseases 0.000 abstract 2
- 230000006378 damage Effects 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 2
- 208000012947 ischemia reperfusion injury Diseases 0.000 abstract 2
- 101000668058 Infectious salmon anemia virus (isolate Atlantic salmon/Norway/810/9/99) RNA-directed RNA polymerase catalytic subunit Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Marine Sciences & Fisheries (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55793504P | 2004-03-31 | 2004-03-31 | |
| PCT/US2005/010822 WO2005097172A2 (en) | 2004-03-31 | 2005-03-30 | Adrenomedullin and adrenomedullin binding protein for ischemia/reperfusion treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE500836T1 true ATE500836T1 (de) | 2011-03-15 |
Family
ID=35125617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05732325T ATE500836T1 (de) | 2004-03-31 | 2005-03-30 | Adrenomedullin und adrenomedullin-bindungsprotein zur ischämie/reperfusionsbehandlung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9101593B2 (de) |
| EP (1) | EP1742651B1 (de) |
| JP (1) | JP4914344B2 (de) |
| AT (1) | ATE500836T1 (de) |
| AU (1) | AU2005231395B2 (de) |
| CA (1) | CA2562957C (de) |
| DE (1) | DE602005026794D1 (de) |
| WO (1) | WO2005097172A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8703693B2 (en) | 2004-03-31 | 2014-04-22 | The Feinstein Institute For Medical Research | Adrenomedullin and adrenomedullin binding protein for ischemia/reperfusion treatment |
| ATE500836T1 (de) | 2004-03-31 | 2011-03-15 | The Feinstein Inst Medical Res | Adrenomedullin und adrenomedullin-bindungsprotein zur ischämie/reperfusionsbehandlung |
| JP4830093B2 (ja) * | 2005-04-08 | 2011-12-07 | 国立大学法人 宮崎大学 | 非細菌性の炎症性疾患の予防又は治療剤 |
| AU2012315586B2 (en) * | 2011-09-29 | 2017-07-20 | Mayo Foundation For Medical Education And Research | Aromatic-cationic peptides and methods for using same |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2774769B2 (ja) * | 1993-04-26 | 1998-07-09 | 賢治 寒川 | アドレノメデュリン |
| US5679546A (en) * | 1993-09-24 | 1997-10-21 | Cytomed, Inc. | Chimeric proteins which block complement activation |
| GB9624731D0 (en) | 1996-11-28 | 1997-01-15 | Univ Leicester | Complement inhibitor |
| US6620615B1 (en) * | 1999-04-23 | 2003-09-16 | Curagen Corporation | G-protein coupled receptor—encoding nucleic acids |
| DE60025008T2 (de) | 1999-09-10 | 2006-09-14 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Bestimmung von adrenomedullin-bindenden proteinen |
| US6864237B2 (en) * | 2002-05-17 | 2005-03-08 | Ping Wang | Treatment of shock using adrenomedullin and adrenomedullin binding protein-1 |
| US6884781B2 (en) | 2003-05-16 | 2005-04-26 | Ping Wang | Treatment of shock using adrenomedullin binding protein-1 |
| US20080051315A1 (en) | 2003-12-11 | 2008-02-28 | Eric Kandel | Grp Receptor-Related Methods for the Treating and Preventing Fear-Related Disorders |
| US8703693B2 (en) | 2004-03-31 | 2014-04-22 | The Feinstein Institute For Medical Research | Adrenomedullin and adrenomedullin binding protein for ischemia/reperfusion treatment |
| ATE500836T1 (de) | 2004-03-31 | 2011-03-15 | The Feinstein Inst Medical Res | Adrenomedullin und adrenomedullin-bindungsprotein zur ischämie/reperfusionsbehandlung |
| WO2006124770A2 (en) | 2005-05-13 | 2006-11-23 | The Feinstein Institute For Medical Research | Treatment of sepsis and inflammation with alpha2a adrenergic antagonists |
| CA2608271C (en) | 2005-05-13 | 2016-01-19 | The Feinstein Institute For Medical Research | Milk fat globule epidermal growth factor-factor viii and sepsis |
| WO2009064448A1 (en) | 2007-11-15 | 2009-05-22 | The Feinstein Institute For Medical Research | Prevention and treatment of inflammation and organ injury after ischemia/reperfusion using mfg-e8 |
| US8324151B2 (en) | 2007-11-20 | 2012-12-04 | The Feinstein Institute For Medical Research | Treatment of sepsis and septic shock using ghrelin and growth hormone |
-
2005
- 2005-03-30 AT AT05732325T patent/ATE500836T1/de not_active IP Right Cessation
- 2005-03-30 WO PCT/US2005/010822 patent/WO2005097172A2/en not_active Ceased
- 2005-03-30 JP JP2007506527A patent/JP4914344B2/ja not_active Expired - Fee Related
- 2005-03-30 CA CA2562957A patent/CA2562957C/en not_active Expired - Fee Related
- 2005-03-30 DE DE602005026794T patent/DE602005026794D1/de not_active Expired - Lifetime
- 2005-03-30 AU AU2005231395A patent/AU2005231395B2/en not_active Ceased
- 2005-03-30 EP EP05732325A patent/EP1742651B1/de not_active Expired - Lifetime
-
2014
- 2014-02-28 US US14/193,284 patent/US9101593B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007537160A (ja) | 2007-12-20 |
| EP1742651A2 (de) | 2007-01-17 |
| AU2005231395B2 (en) | 2011-06-16 |
| JP4914344B2 (ja) | 2012-04-11 |
| WO2005097172A3 (en) | 2006-03-30 |
| AU2005231395A1 (en) | 2005-10-20 |
| DE602005026794D1 (de) | 2011-04-21 |
| EP1742651B1 (de) | 2011-03-09 |
| EP1742651A4 (de) | 2009-08-05 |
| US9101593B2 (en) | 2015-08-11 |
| CA2562957A1 (en) | 2005-10-20 |
| US20140342988A1 (en) | 2014-11-20 |
| CA2562957C (en) | 2013-05-21 |
| WO2005097172A2 (en) | 2005-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |