ATE504205T1 - Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen - Google Patents

Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen

Info

Publication number
ATE504205T1
ATE504205T1 AT01986449T AT01986449T ATE504205T1 AT E504205 T1 ATE504205 T1 AT E504205T1 AT 01986449 T AT01986449 T AT 01986449T AT 01986449 T AT01986449 T AT 01986449T AT E504205 T1 ATE504205 T1 AT E504205T1
Authority
AT
Austria
Prior art keywords
produce
immunogenicity
proteins
determining
immune response
Prior art date
Application number
AT01986449T
Other languages
English (en)
Inventor
David Estell
Fiona Harding
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/677,822 external-priority patent/US6936249B1/en
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of ATE504205T1 publication Critical patent/ATE504205T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT01986449T 2000-10-02 2001-09-26 Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen ATE504205T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/677,822 US6936249B1 (en) 1998-04-15 2000-10-02 Proteins producing an altered immunogenic response and methods of making and using the same
US09/768,080 US6897049B1 (en) 1998-04-15 2001-01-23 Proteins producing an altered immunogenic response and methods of making and using the same
PCT/US2001/030062 WO2002040997A2 (en) 2000-10-02 2001-09-26 Production and use of proteins producing an altered immunogenic response

Publications (1)

Publication Number Publication Date
ATE504205T1 true ATE504205T1 (de) 2011-04-15

Family

ID=27101907

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01986449T ATE504205T1 (de) 2000-10-02 2001-09-26 Methode zur bestimmung der immunogenität von proteinen, die eine veränderte immunantwort hervorrufen

Country Status (7)

Country Link
EP (1) EP1469721B1 (de)
JP (1) JP5126761B2 (de)
AT (1) ATE504205T1 (de)
AU (1) AU2002237646A1 (de)
CA (1) CA2424720C (de)
DE (1) DE60144399D1 (de)
WO (1) WO2002040997A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL210859B1 (pl) * 2001-03-23 2012-03-30 Genencor Int Odmiana subtylizyny zawierająca zmieniony epitop limfocytów T, kwas nukleinowy kodujący tę odmianę subtylizyny, wektor ekspresyjny i komórka gospodarza zawierająca kwas nukleinowy oraz kompozycje zawierające tę odmianę subtylizyny
EP1512004B1 (de) * 2002-06-11 2006-03-15 MERCK PATENT GmbH Methode zur identifizierung und eliminierung von t-zell epitopen
WO2005119259A2 (en) * 2004-04-26 2005-12-15 Genencor International, Inc. Population based prediction methods for immune response determinations and methods for verifying immunological response data
US20100192985A1 (en) 2008-11-11 2010-08-05 Wolfgang Aehle Compositions and methods comprising serine protease variants
CN102064161B (zh) * 2010-11-12 2013-09-04 嘉兴斯达微电子有限公司 一种优化的智能功率模块的功率封装结构
GB2499180A (en) * 2011-09-08 2013-08-14 Alcyomics Ltd Method of identifying sensitizers or allergens using measurements of T-cell proliferation and/or IFN Gamma
EP4525615A2 (de) 2022-05-14 2025-03-26 Novozymes A/S Zusammensetzungen und verfahren zur prävention, behandlung, unterdrückung und/oder beseitigung von phytopathogenen befällen und infektionen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
IE65767B1 (en) 1986-04-30 1995-11-15 Genencor Int Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors
US5470560A (en) * 1987-01-20 1995-11-28 Genentech, Inc. Method for evaluating immunogenicity
FI932561L (fi) * 1990-12-05 1993-06-04 Novo Nordisk As Proteiner med foeraendrade epitoper och foerfaranden foer deras framstaellning
WO1999006061A1 (en) * 1997-07-29 1999-02-11 The Administrators Of The Tulane Educational Fund Prediction, detection, and design of t cell epitopes
US6642011B2 (en) * 1998-04-15 2003-11-04 Genencor International, Inc. Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
AU776910B2 (en) * 1998-12-08 2004-09-23 Merck Patent Gesellschaft Mit Beschrankter Haftung Modifying protein immunogenicity

Also Published As

Publication number Publication date
CA2424720C (en) 2012-04-03
WO2002040997A2 (en) 2002-05-23
DE60144399D1 (de) 2011-05-19
EP1469721B1 (de) 2011-04-06
WO2002040997A3 (en) 2004-08-12
JP2004528013A (ja) 2004-09-16
AU2002237646A1 (en) 2002-05-27
CA2424720A1 (en) 2002-05-23
EP1469721A2 (de) 2004-10-27
WO2002040997A9 (en) 2002-07-25
JP5126761B2 (ja) 2013-01-23

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