ATE505263T1 - METHOD FOR CRYOGRANULATION AND STORAGE OF ALLERGENS - Google Patents

METHOD FOR CRYOGRANULATION AND STORAGE OF ALLERGENS

Info

Publication number
ATE505263T1
ATE505263T1 AT04803030T AT04803030T ATE505263T1 AT E505263 T1 ATE505263 T1 AT E505263T1 AT 04803030 T AT04803030 T AT 04803030T AT 04803030 T AT04803030 T AT 04803030T AT E505263 T1 ATE505263 T1 AT E505263T1
Authority
AT
Austria
Prior art keywords
low temperature
temperature particles
relates
particles
storing
Prior art date
Application number
AT04803030T
Other languages
German (de)
Inventor
Martin Richter-Friis
Signe Andersen
Original Assignee
Alk Abello As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alk Abello As filed Critical Alk Abello As
Priority claimed from PCT/DK2004/000878 external-priority patent/WO2005058474A1/en
Application granted granted Critical
Publication of ATE505263T1 publication Critical patent/ATE505263T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Glanulating (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a volume production method for preparing active medicament components such as allergenic products. The present invention also relates to a container containing low temperature particles of liquid combinations of the allergenic products, and further relates to low temperature particles of the allergenic products. The method for preparing and storing low temperature particles for an active medicament is characterized by using a container containing low temperature medium (such as liquid nitrogen), and storing the low temperature particles in a same container. The low temperature particles do not undergo freeze-drying before storage and processing.
AT04803030T 2003-12-19 2004-12-17 METHOD FOR CRYOGRANULATION AND STORAGE OF ALLERGENS ATE505263T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200301896 2003-12-19
US53167903P 2003-12-23 2003-12-23
PCT/DK2004/000878 WO2005058474A1 (en) 2003-12-19 2004-12-17 Cryogranulation and storage method for active pharmaceutical agents

Publications (1)

Publication Number Publication Date
ATE505263T1 true ATE505263T1 (en) 2011-04-15

Family

ID=34973435

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04803030T ATE505263T1 (en) 2003-12-19 2004-12-17 METHOD FOR CRYOGRANULATION AND STORAGE OF ALLERGENS

Country Status (6)

Country Link
JP (1) JP4755992B2 (en)
CN (2) CN102657863A (en)
AT (1) ATE505263T1 (en)
DE (1) DE602004032262D1 (en)
DK (1) DK1697033T3 (en)
ES (1) ES2363342T3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127173B (en) * 2013-03-06 2015-01-21 苏州市红冠庄国药饮片有限公司 Atomizing multi-layer covering and crystallizing process for producing beer blood crystal
CN114160040B (en) * 2021-12-09 2022-07-12 广州风行乳业股份有限公司 Liquid nitrogen cryogenic granulation equipment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5242846B2 (en) * 1974-04-03 1977-10-27
CA2338766A1 (en) * 1998-07-31 2000-02-10 Eli Lilly And Company Cryogranulation of activated protein c
CA2397404C (en) * 2000-01-14 2008-12-02 Brown University Research Foundation Micronized freeze-dried particles
ATE414773T1 (en) * 2000-11-16 2008-12-15 Alk Abello As MUTANT ALLERGENS
AUPR750501A0 (en) * 2001-09-05 2001-09-27 Gauci, Mark Products comprising quantum of bioparticles and method for production thereof

Also Published As

Publication number Publication date
CN1894026A (en) 2007-01-10
CN1894026B (en) 2012-01-25
DK1697033T3 (en) 2011-06-27
JP4755992B2 (en) 2011-08-24
ES2363342T3 (en) 2011-08-01
JP2007514490A (en) 2007-06-07
DE602004032262D1 (en) 2011-05-26
CN102657863A (en) 2012-09-12

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties