ATE506965T1 - Verfahren zur identifikation von polypeptid- antigenen im zusammenhang mit störungen durch aberrante zellproliferation - Google Patents

Verfahren zur identifikation von polypeptid- antigenen im zusammenhang mit störungen durch aberrante zellproliferation

Info

Publication number
ATE506965T1
ATE506965T1 AT02797854T AT02797854T ATE506965T1 AT E506965 T1 ATE506965 T1 AT E506965T1 AT 02797854 T AT02797854 T AT 02797854T AT 02797854 T AT02797854 T AT 02797854T AT E506965 T1 ATE506965 T1 AT E506965T1
Authority
AT
Austria
Prior art keywords
antibodies
mitotic
polypeptide antigens
cdc
cell
Prior art date
Application number
AT02797854T
Other languages
English (en)
Inventor
Arthur D Levinson
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE506965T1 publication Critical patent/ATE506965T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT02797854T 2001-09-05 2002-09-04 Verfahren zur identifikation von polypeptid- antigenen im zusammenhang mit störungen durch aberrante zellproliferation ATE506965T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31750401P 2001-09-05 2001-09-05
PCT/US2002/028176 WO2003020909A2 (en) 2001-09-05 2002-09-04 Methods for the identification of polypeptide antigens associated with disorders involving aberrant cell proliferation and compositions useful for the treatment of such disorders

Publications (1)

Publication Number Publication Date
ATE506965T1 true ATE506965T1 (de) 2011-05-15

Family

ID=23233944

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02797854T ATE506965T1 (de) 2001-09-05 2002-09-04 Verfahren zur identifikation von polypeptid- antigenen im zusammenhang mit störungen durch aberrante zellproliferation

Country Status (17)

Country Link
EP (1) EP1432446B1 (de)
JP (2) JP5224632B2 (de)
KR (3) KR20100061863A (de)
CN (2) CN1578673A (de)
AT (1) ATE506965T1 (de)
AU (1) AU2002332838B2 (de)
BR (1) BR0212641A (de)
CA (1) CA2457541C (de)
DE (1) DE60239881D1 (de)
DK (1) DK1432446T3 (de)
HU (1) HUP0500617A3 (de)
IL (2) IL160659A0 (de)
MX (1) MXPA04002084A (de)
NZ (1) NZ531515A (de)
PL (1) PL374363A1 (de)
WO (1) WO2003020909A2 (de)
ZA (1) ZA200401751B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088387B2 (en) * 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
KR101145506B1 (ko) * 2003-05-20 2012-05-15 이뮤노젠 아이엔씨 새로운 메이탠시노이드를 포함하는 개선된 세포독성체
US7276497B2 (en) 2003-05-20 2007-10-02 Immunogen Inc. Cytotoxic agents comprising new maytansinoids
NO347360B1 (no) * 2003-10-10 2023-09-25 Immunogen Inc Cellebindingsmiddelmaytansinoid-konjugat med formel trastuzumab-SMCC-DM1 eller trastuzumab-SIABDM1, fremgangsmåte for fremstilling av disse og en in vitro fremgangsmåte for å styre maytansinoider til en valgt cellepopulasjon eller for å eliminere celler, samt anvendelse.
HUE029925T2 (en) * 2008-04-02 2017-04-28 Macrogenics Inc HER2 / neu-specific antibodies and methods using them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2026147C (en) * 1989-10-25 2006-02-07 Ravi J. Chari Cytotoxic agents comprising maytansinoids and their therapeutic use
AU770952B2 (en) * 1999-03-01 2004-03-11 Genentech Inc. Antibodies for cancer therapy and diagnosis
BR0015224A (pt) * 1999-10-29 2002-07-09 Genentech Inc Anticorpo anti-antìgeno de célula estaminal prostática (psca) isolado, anticorpo monoclonal anti-psca, ácido nucleico isolado, vetor de expressão, célula, célula hospedeira, método de produção de anticorpo, composição método in vitro para matar uma célula cancerosa que expresse psca, uso de uma anticorpo monoclonal anti-psca e artigo industrializado
CA2397416A1 (en) * 2000-01-26 2001-08-02 Jonathan Cohen A system for developing assays for personalized medicine

Also Published As

Publication number Publication date
NZ531515A (en) 2007-11-30
IL160659A0 (en) 2004-08-31
BR0212641A (pt) 2005-04-12
KR20090104925A (ko) 2009-10-06
HUP0500617A2 (hu) 2005-10-28
WO2003020909A3 (en) 2003-11-20
EP1432446A4 (de) 2004-09-08
MXPA04002084A (es) 2004-06-07
CN1578673A (zh) 2005-02-09
JP5224632B2 (ja) 2013-07-03
EP1432446B1 (de) 2011-04-27
HUP0500617A3 (en) 2012-05-02
EP1432446A2 (de) 2004-06-30
CN101446590A (zh) 2009-06-03
KR20040044850A (ko) 2004-05-31
ZA200401751B (en) 2005-07-27
KR20100061863A (ko) 2010-06-09
DE60239881D1 (de) 2011-06-09
AU2002332838B2 (en) 2007-08-02
JP2005517155A (ja) 2005-06-09
CA2457541A1 (en) 2003-03-13
DK1432446T3 (da) 2011-07-18
WO2003020909A2 (en) 2003-03-13
PL374363A1 (pl) 2005-10-17
JP2010280691A (ja) 2010-12-16
CA2457541C (en) 2013-01-08
IL160659A (en) 2011-07-31

Similar Documents

Publication Publication Date Title
WO2005009389A3 (en) Anaplastic lymphoma kinase modulators and methods of use
WO2020139926A3 (en) Anti-ctla4 antibodies and methods of use thereof
WO2003050064A3 (en) Mitotic kinesin inhibitors
WO2003049678A3 (en) Mitotic kinesin inhibitors
WO2003049679A3 (en) Mitotic kinesin inhibitors
WO2003050122A3 (en) Mitotic kinesin inhibitors
DE69737867D1 (de) Zielgerichtete kombinations-immuntherapie für krebs
UA114879C2 (uk) Антитіло до cd38 для лікування раку
MXPA05006568A (es) Compuestos de pirazol aciclico para la inhibicion de proteina cinasa-2 activada por proteina cinasa activada por mitogenos.
WO2023169896A8 (en) BINDING MOLECULES AGAINST FRα
AU2001233726A1 (en) Farnesyl protein transferase inhibitors for treating breast cancer
WO2003048301A3 (en) Anti-hla-dr antibodies and the methods of using thereof
WO2023201234A3 (en) Anti-variable muc1* antibodies and uses thereof
WO2004089294A3 (en) Compositions, methods and kits relating to her-2 cleavage
EA200500300A1 (ru) Цитотоксические агенты, содержащие новые сильнодействующие таксаны, и их терапевтическое применение
MX2009010034A (es) Pirimidodiazepinas sustituidas utiles inhibidores de la plk1.
WO2005065183A3 (en) Mitotic kinesin inhibitors
WO2024077023A3 (en) Cereblon-recruiting bcl-xl/bcl-2 dual degraders
WO2003084475A3 (en) INHIBITORS OF THE S100-p53 PROTEIN-PROTEIN INTERACTION AND METHOD OF INHIBITING CANCER EMPLOYING THE SAME
WO2021217130A3 (en) Chimeric antigen receptors targeting cd19 and use thereof
MX2024013871A (es) Agentes aglutinantes 5t4 y usos de los mismos
WO2005090406A3 (en) Antibodies binding to ephb4 for inhibiting angiogenesis and tumor growth
DE60239881D1 (de) Verfahren zur identifikation von polypeptid-antigenen im zusammenhang mit störungen durch aberrante zellproliferation
WO2021024133A3 (en) Biopharmacuetical compositions and related methods
PL1732926T3 (pl) Inhibitory kinezyn motorycznych

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties