ATE507209T1 - Referenzstandard zur charakterisierung von rosuvastatin - Google Patents

Referenzstandard zur charakterisierung von rosuvastatin

Info

Publication number
ATE507209T1
ATE507209T1 AT04812772T AT04812772T ATE507209T1 AT E507209 T1 ATE507209 T1 AT E507209T1 AT 04812772 T AT04812772 T AT 04812772T AT 04812772 T AT04812772 T AT 04812772T AT E507209 T1 ATE507209 T1 AT E507209T1
Authority
AT
Austria
Prior art keywords
rosuvastatin
characterization
reference standard
standard
analysis
Prior art date
Application number
AT04812772T
Other languages
English (en)
Inventor
Nina Finkelstein
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34676616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE507209(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE507209T1 publication Critical patent/ATE507209T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT04812772T 2003-12-02 2004-12-02 Referenzstandard zur charakterisierung von rosuvastatin ATE507209T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52644903P 2003-12-02 2003-12-02
PCT/US2004/040329 WO2005056534A1 (en) 2003-12-02 2004-12-02 Reference standard for characterization of rosuvastatin

Publications (1)

Publication Number Publication Date
ATE507209T1 true ATE507209T1 (de) 2011-05-15

Family

ID=34676616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04812772T ATE507209T1 (de) 2003-12-02 2004-12-02 Referenzstandard zur charakterisierung von rosuvastatin

Country Status (13)

Country Link
US (6) US7244844B2 (de)
EP (1) EP1689723B1 (de)
JP (1) JP4733047B2 (de)
KR (1) KR100887264B1 (de)
CN (1) CN1894221B (de)
AT (1) ATE507209T1 (de)
CA (1) CA2546894C (de)
DE (1) DE602004032465D1 (de)
ES (1) ES2364143T3 (de)
IL (1) IL175511A (de)
PT (1) PT1689723E (de)
TW (1) TWI351958B (de)
WO (1) WO2005056534A1 (de)

Families Citing this family (15)

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GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
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GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
KR100887264B1 (ko) * 2003-12-02 2009-03-06 테바 파마슈티컬 인더스트리즈 리미티드 로수바스타틴의 특성화를 위한 기준 표준물
US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
CA2683975A1 (en) 2005-02-22 2006-08-31 Teva Pharmaceutical Industries Ltd. Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof
JP5235676B2 (ja) * 2005-12-20 2013-07-10 レツク・フアーマシユーテイカルズ・デー・デー （ｅ）−７−〔４−（４−フルオロフェニル）−６−イソプロピル−２−〔メチル（メチルスルホニル）アミノ〕ピリミジン−５−イル〕−（３ｒ，５ｓ）−３，５−ジヒドロキシヘプタ−６−エン酸を含む医薬組成物
JP5330225B2 (ja) * 2007-03-13 2013-10-30 テバ ファーマシューティカル インダストリーズ リミティド トリオール型ロスバスタチン
EP2189456A1 (de) * 2008-11-14 2010-05-26 LEK Pharmaceuticals d.d. Neue Omeprazol-Verbindungen
ES2554623T3 (es) 2008-12-30 2015-12-22 Arqule, Inc. Compuestos de 5,6-dihidro-6-fenilbenzo[f]isoquinolin-2-amina sustituida
CN103454352B (zh) * 2013-07-30 2015-07-15 广东先强药业有限公司 一种hplc法测定瑞舒伐他汀钙的含量及其有关物质的方法
CN103776939A (zh) * 2014-02-11 2014-05-07 润泽制药(苏州)有限公司 瑞舒伐他汀钙制剂有关物质的制备检测方法
CN108398501A (zh) * 2018-03-02 2018-08-14 海南通用三洋药业有限公司 一种检测瑞舒伐他汀钙有关物质的方法
CN109020902B (zh) * 2018-07-23 2020-06-02 唯智医药科技（北京）有限公司 一种瑞舒伐他汀钙杂质及其制备方法与用途
CN114280181B (zh) * 2021-12-23 2024-06-18 浙江海翔川南药业有限公司 一种瑞舒伐他汀中间体及其有关物质的检测方法

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US4739073A (en) 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
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WO1992022560A1 (fr) 1991-06-19 1992-12-23 Shionogi Seiyaku Kabushiki Kaisha Intermediaire optiquement actif et production de celui-ci
JP2648897B2 (ja) 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
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GB9903472D0 (en) 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0001621D0 (en) 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
US6777552B2 (en) 2001-08-16 2004-08-17 Teva Pharmaceutical Industries, Ltd. Processes for preparing calcium salt forms of statins
GB0028429D0 (en) 2000-11-22 2001-01-10 Astrazeneca Ab Therapy
HUP0500616A3 (en) * 2001-08-16 2011-07-28 Teva Pharma Processes for preparing calcium salt forms of statins
SE0103509D0 (sv) 2001-10-19 2001-10-19 Astrazeneca Ab Rosuvastatin in pre demented states
KR100511533B1 (ko) 2002-04-09 2005-08-31 임광민 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법
AR039836A1 (es) 2002-05-21 2005-03-02 Ranbaxy Lab Ltd Proceso para la preparacion de un aldehido de pirimidina util para la preparacion de rosuvastatina
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
CN1742000A (zh) 2002-12-10 2006-03-01 兰贝克赛实验室有限公司 制备若舒伐他汀的方法
AU2003269478A1 (en) 2003-08-27 2005-03-16 Hetero Drugs Limited A novel process for amorphous rosuvastatin calcium
CN1886383A (zh) * 2003-10-22 2006-12-27 兰贝克赛实验室有限公司 无定形罗苏伐他汀钙的制备方法
WO2005051921A1 (en) 2003-11-24 2005-06-09 Teva Pharmaceutical Industries Ltd. Crystalline ammonium salts of rosuvastatin
KR100887264B1 (ko) * 2003-12-02 2009-03-06 테바 파마슈티컬 인더스트리즈 리미티드 로수바스타틴의 특성화를 위한 기준 표준물
US20080234302A1 (en) 2004-09-27 2008-09-25 Mohammad Rafeeq Novel Processes for Preparing Amorphous Rosuvastatin Calcium and a Novel Polymorphic Form of Rosuvastatin Sodium
JP2008528542A (ja) 2005-01-31 2008-07-31 チバ ホールディング インコーポレーテッド ロスバスタチンカルシウム塩の結晶形
EP1863773A1 (de) 2005-03-22 2007-12-12 Unichem Laboratories Limited Verfahren zur herstellung von rosuvastatin
EP1869005A1 (de) 2005-04-04 2007-12-26 Unichem Laboratories Limited Verfahren zur herstellung des calciumsalzes von rosuvastatin
ES2564807T5 (es) 2005-06-24 2019-02-26 Lek Pharmaceuticals Proceso para preparación de rosuvastatina de calcio amorfa pura
EP2508514B1 (de) 2005-06-24 2017-10-18 LEK Pharmaceuticals d.d. Verfahren zur Herstellung von amorphem Rosuvastatincalcium frei von Verunreinigungen
GB0514078D0 (en) 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process

Also Published As

Publication number Publication date
US8487097B2 (en) 2013-07-16
US20070255059A1 (en) 2007-11-01
US20090188305A1 (en) 2009-07-30
KR20060098396A (ko) 2006-09-18
JP4733047B2 (ja) 2011-07-27
TWI351958B (en) 2011-11-11
IL175511A0 (en) 2006-09-05
DE602004032465D1 (de) 2011-06-09
US7244844B2 (en) 2007-07-17
KR100887264B1 (ko) 2009-03-06
CA2546894A1 (en) 2005-06-23
US20070249830A1 (en) 2007-10-25
JP2007512354A (ja) 2007-05-17
IL175511A (en) 2011-11-30
US7692010B2 (en) 2010-04-06
US7741482B2 (en) 2010-06-22
US20070249831A1 (en) 2007-10-25
US7692008B2 (en) 2010-04-06
US20070244321A1 (en) 2007-10-18
PT1689723E (pt) 2011-07-06
EP1689723A1 (de) 2006-08-16
US7692009B2 (en) 2010-04-06
EP1689723B1 (de) 2011-04-27
CN1894221A (zh) 2007-01-10
ES2364143T3 (es) 2011-08-25
TW200522959A (en) 2005-07-16
WO2005056534A1 (en) 2005-06-23
CN1894221B (zh) 2012-08-08
CA2546894C (en) 2009-09-08
US20050187234A1 (en) 2005-08-25

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