ATE508167T1 - Membranaktive polymere - Google Patents

Membranaktive polymere

Info

Publication number
ATE508167T1
ATE508167T1 AT04707130T AT04707130T ATE508167T1 AT E508167 T1 ATE508167 T1 AT E508167T1 AT 04707130 T AT04707130 T AT 04707130T AT 04707130 T AT04707130 T AT 04707130T AT E508167 T1 ATE508167 T1 AT E508167T1
Authority
AT
Austria
Prior art keywords
membrane
active polymers
polymers
delivery
compounds
Prior art date
Application number
AT04707130T
Other languages
English (en)
Inventor
David Rozema
Darren Wakefield
Original Assignee
Mirus Bio Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mirus Bio Corp filed Critical Mirus Bio Corp
Application granted granted Critical
Publication of ATE508167T1 publication Critical patent/ATE508167T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measurement Of Length, Angles, Or The Like Using Electric Or Magnetic Means (AREA)
AT04707130T 2003-01-31 2004-01-30 Membranaktive polymere ATE508167T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44390603P 2003-01-31 2003-01-31
US10/765,668 US7871818B2 (en) 2003-01-31 2004-01-27 Membrane active polymers
PCT/US2004/003573 WO2004070019A2 (en) 2003-01-31 2004-01-30 Membrane active polymers

Publications (1)

Publication Number Publication Date
ATE508167T1 true ATE508167T1 (de) 2011-05-15

Family

ID=32776200

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04707130T ATE508167T1 (de) 2003-01-31 2004-01-30 Membranaktive polymere

Country Status (5)

Country Link
US (1) US7871818B2 (de)
EP (1) EP1587869B1 (de)
AT (1) ATE508167T1 (de)
DE (1) DE602004032515D1 (de)
WO (1) WO2004070019A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007084797A1 (en) * 2006-01-23 2007-07-26 Abbott Laboratories Chemically modified polycation polymer for sirna delivery
US20100035248A1 (en) * 2007-06-15 2010-02-11 Rastislav Levicky Surface-based nucleic acid assays employing morpholinos
WO2009140423A2 (en) * 2008-05-13 2009-11-19 University Of Washington Targeted polymer bioconjugates
CA2972694C (en) * 2008-05-13 2020-02-11 University Of Washington Diblock copolymers and polynucleotide complexes thereof for delivery into cells
AU2009246321A1 (en) * 2008-05-13 2009-11-19 Phaserx, Inc. Polymeric carrier
EP2285853B1 (de) 2008-05-13 2013-02-27 University of Washington Micellenanordnungen
KR20110020804A (ko) * 2008-05-13 2011-03-03 유니버시티 오브 워싱톤 치료제의 세포내 전달을 위한 미셀
JP2012500793A (ja) 2008-08-22 2012-01-12 ユニヴァーシティ オブ ワシントン 細胞内デリバリーのための異種性ポリマーミセル
MX2011004242A (es) 2008-11-06 2011-07-20 Univ Washington Copolimeros multibloque.
EP2352522A4 (de) 2008-11-06 2014-03-05 Univ Washington Bispezifische hilfsstoffe für intrazelluläre freisetzung
WO2010077678A2 (en) 2008-12-08 2010-07-08 University Of Washington Omega-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization
US9415113B2 (en) 2009-11-18 2016-08-16 University Of Washington Targeting monomers and polymers having targeting blocks
AU2014296278C1 (en) 2013-07-30 2023-02-02 Genevant Sciences Gmbh Block copolymers and their conjugates or complexes with oligonucleotides
JP2018509387A (ja) 2015-01-21 2018-04-05 フェーズアールエックス インコーポレイテッド 細胞に治療および診断剤を送達するための方法、組成物、ならびにシステム
EP3562510A4 (de) 2016-12-30 2021-01-06 Genevant Sciences GmbH Verzweigte peg-moleküle sowie zugehörige zusammensetzungen und verfahren
GB201804233D0 (en) 2018-03-16 2018-05-02 Univ Warwick Cryopreserving processes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241294A (en) * 1967-10-23 1971-08-04 Ici Ltd A PROCESS FOR THE PREPARATION OF AMIDE-ACID DERIVATIVES OF alpha,beta-UNSATURATED DICARBOXYLIC AND ANHYDRIDE COPOLYMERS
EP0087957B1 (de) * 1982-02-27 1986-11-26 Kuraray Co., Ltd. Neocarzinostatinkomplexe, Verfahren zu ihrer Herstellung und Antitumormittel, das diese Komplexe als aktive Komponente enhält
US5118551A (en) * 1990-03-27 1992-06-02 Allied-Signal Inc. Method to impart stain resistance to polyamide textile substrates
AUPO379596A0 (en) * 1996-11-22 1996-12-19 Soltec Research Pty Ltd Percutaneous delivery system
GB9717905D0 (en) * 1997-08-22 1997-10-29 Univ Aston Lipid-containing compositions and uses thereof
DE69941447D1 (de) * 1998-01-05 2009-11-05 Univ Washington Erhöhter transport unter benutzung membranzerstörender stoffe
US20050153926A1 (en) * 1998-12-04 2005-07-14 Adams Christopher P. Method for the immobilization of oligonucleotides
US20020052335A1 (en) * 1999-11-29 2002-05-02 Rozema David B. Charge reversal of polyion complexes
WO2001049841A1 (en) * 1999-12-31 2001-07-12 Mirus Corporation Polyampholytes for delivering polyions to a cell
US6740336B2 (en) * 2002-10-04 2004-05-25 Mirus Corporation Process for generating multilayered particles

Also Published As

Publication number Publication date
DE602004032515D1 (de) 2011-06-16
EP1587869B1 (de) 2011-05-04
WO2004070019A3 (en) 2005-04-14
US20040151775A1 (en) 2004-08-05
WO2004070019A2 (en) 2004-08-19
US7871818B2 (en) 2011-01-18
EP1587869A4 (de) 2006-02-22
EP1587869A2 (de) 2005-10-26

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Legal Events

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