ATE509931T1 - Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür - Google Patents
Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafürInfo
- Publication number
- ATE509931T1 ATE509931T1 AT08732552T AT08732552T ATE509931T1 AT E509931 T1 ATE509931 T1 AT E509931T1 AT 08732552 T AT08732552 T AT 08732552T AT 08732552 T AT08732552 T AT 08732552T AT E509931 T1 ATE509931 T1 AT E509931T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- derivatives
- azaadamantanester
- carbamat
- application
- Prior art date
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical class NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000203 mixture Chemical class 0.000 abstract 2
- -1 azaadamantane ester Chemical class 0.000 abstract 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89674507P | 2007-03-23 | 2007-03-23 | |
| PCT/US2008/057641 WO2008118742A1 (en) | 2007-03-23 | 2008-03-20 | Azaadamantane ester and carbamate derivatives and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE509931T1 true ATE509931T1 (de) | 2011-06-15 |
Family
ID=39788934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08732552T ATE509931T1 (de) | 2007-03-23 | 2008-03-20 | Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8163916B2 (de) |
| EP (1) | EP2129672B1 (de) |
| JP (2) | JP5566698B2 (de) |
| CN (2) | CN101641355A (de) |
| AT (1) | ATE509931T1 (de) |
| CA (1) | CA2679870A1 (de) |
| ES (1) | ES2363998T3 (de) |
| MX (1) | MX2009010174A (de) |
| WO (1) | WO2008118742A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
| WO2010145208A1 (en) * | 2009-06-19 | 2010-12-23 | Abbott Laboratories | Diazahomoadamantane derivatives and methods of use thereof |
| WO2010122178A2 (en) * | 2010-05-25 | 2010-10-28 | Symrise Gmbh & Co. Kg | Cyclohexyl carbamate compounds as skin and/or hair lightening actives |
| EP2389922A1 (de) * | 2010-05-25 | 2011-11-30 | Symrise AG | Cyclohexylcarbamatverbindungen als Anti-ageing-Wirkstoffe |
| JP5838497B2 (ja) * | 2010-05-25 | 2016-01-06 | シムライズ アーゲー | 抗セルライト有効成分としてのシクロヘキシルカルバメート化合物 |
| EP2619205B1 (de) | 2010-09-23 | 2017-05-17 | AbbVie Bahamas Ltd. | Monohydrat eines azaadamantanderivates |
| US8969562B2 (en) | 2013-03-12 | 2015-03-03 | Abbvie, Inc. | Azaadamantane formate ester and process for preparing azaadamantane derivatives |
| TW201617342A (zh) * | 2014-07-11 | 2016-05-16 | 阿法馬根公司 | 調節α７活性之啶類 |
| CA2971413A1 (en) | 2014-12-16 | 2016-06-23 | Axovant Sciences Gmbh | Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors |
| CN107847494A (zh) | 2015-06-10 | 2018-03-27 | 阿考温特科学股份有限公司 | 作为α7‑烟碱乙酰胆碱受体激动剂的氨基苯并异噁唑化合物 |
| US10428062B2 (en) | 2015-08-12 | 2019-10-01 | Axovant Sciences Gmbh | Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8523211D0 (en) | 1985-09-19 | 1985-10-23 | Beecham Group Plc | Compounds |
| HU202108B (en) | 1986-07-30 | 1991-02-28 | Sandoz Ag | Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol |
| EP0329932B1 (de) * | 1988-02-23 | 1995-10-18 | Merrell Pharmaceuticals Inc. | Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln |
| US5140023A (en) * | 1990-04-27 | 1992-08-18 | G. D. Searle & Co. | Azatetracycle compounds |
| US5260303A (en) | 1991-03-07 | 1993-11-09 | G. D. Searle & Co. | Imidazopyridines as serotonergic 5-HT3 antagonists |
| US5521193A (en) * | 1992-06-24 | 1996-05-28 | G. D. Searle & Co. | Benzimidazole compounds |
| US5280028A (en) | 1992-06-24 | 1994-01-18 | G. D. Searle & Co. | Benzimidazole compounds |
| US5434151A (en) | 1992-08-24 | 1995-07-18 | Cytomed, Inc. | Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase |
| US5840903A (en) * | 1992-07-27 | 1998-11-24 | G. D. Searle & Co. | 4-aminomethyl-1-azaadamantane derived benzamides |
| US5399562A (en) | 1994-02-04 | 1995-03-21 | G. D. Searle & Co. | Indolones useful as serotonergic agents |
| AU685225B2 (en) * | 1994-02-10 | 1998-01-15 | Yamanouchi Pharmaceutical Co., Ltd. | Novel carbamate derivative and medicinal composition containing the same |
| CN1332726A (zh) * | 1998-11-02 | 2002-01-23 | 卫福有限公司 | 吡咯烷化合物及其药物用途 |
| MY145722A (en) | 2000-04-27 | 2012-03-30 | Abbott Lab | Diazabicyclic central nervous system active agents |
| JP4616971B2 (ja) * | 2000-07-18 | 2011-01-19 | 田辺三菱製薬株式会社 | １−アザビシクロアルカン化合物およびその医薬用途 |
| WO2008096870A1 (ja) * | 2007-02-09 | 2008-08-14 | Astellas Pharma Inc. | アザ架橋環化合物 |
-
2008
- 2008-03-20 EP EP08732552A patent/EP2129672B1/de active Active
- 2008-03-20 CN CN200880009459A patent/CN101641355A/zh active Pending
- 2008-03-20 AT AT08732552T patent/ATE509931T1/de not_active IP Right Cessation
- 2008-03-20 JP JP2009554736A patent/JP5566698B2/ja not_active Expired - Fee Related
- 2008-03-20 CA CA002679870A patent/CA2679870A1/en not_active Abandoned
- 2008-03-20 US US12/052,036 patent/US8163916B2/en not_active Expired - Fee Related
- 2008-03-20 WO PCT/US2008/057641 patent/WO2008118742A1/en not_active Ceased
- 2008-03-20 ES ES08732552T patent/ES2363998T3/es active Active
- 2008-03-20 CN CN2013100426086A patent/CN103145711A/zh active Pending
- 2008-03-20 MX MX2009010174A patent/MX2009010174A/es active IP Right Grant
-
2012
- 2012-03-23 US US13/427,999 patent/US20120190704A1/en not_active Abandoned
-
2014
- 2014-06-17 JP JP2014124038A patent/JP2014205695A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010522201A (ja) | 2010-07-01 |
| US20120190704A1 (en) | 2012-07-26 |
| US8163916B2 (en) | 2012-04-24 |
| CN103145711A (zh) | 2013-06-12 |
| ES2363998T3 (es) | 2011-08-22 |
| EP2129672B1 (de) | 2011-05-18 |
| US20080255178A1 (en) | 2008-10-16 |
| WO2008118742A1 (en) | 2008-10-02 |
| JP2014205695A (ja) | 2014-10-30 |
| CA2679870A1 (en) | 2008-10-02 |
| CN101641355A (zh) | 2010-02-03 |
| JP5566698B2 (ja) | 2014-08-06 |
| EP2129672A1 (de) | 2009-12-09 |
| EP2129672A4 (de) | 2009-12-09 |
| MX2009010174A (es) | 2009-10-12 |
| HK1133642A1 (en) | 2010-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |