ATE510007T1 - Aus menschlichem fettgewebe gewonnene multipotente stammzellen und diese enthaltende zelluläre therapeutika - Google Patents

Aus menschlichem fettgewebe gewonnene multipotente stammzellen und diese enthaltende zelluläre therapeutika

Info

Publication number
ATE510007T1
ATE510007T1 AT05819135T AT05819135T ATE510007T1 AT E510007 T1 ATE510007 T1 AT E510007T1 AT 05819135 T AT05819135 T AT 05819135T AT 05819135 T AT05819135 T AT 05819135T AT E510007 T1 ATE510007 T1 AT E510007T1
Authority
AT
Austria
Prior art keywords
cells
stem cells
adult stem
cells derived
fat tissue
Prior art date
Application number
AT05819135T
Other languages
English (en)
Inventor
Kyung Sun Kang
Jeong Chan Ra
Jung Ran Park
Original Assignee
Rnl Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38041072&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE510007(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rnl Bio Co Ltd filed Critical Rnl Bio Co Ltd
Application granted granted Critical
Publication of ATE510007T1 publication Critical patent/ATE510007T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14Calcium; Ca chelators; Calcitonin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/44Thiols, e.g. mercaptoethanol
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/80Undefined extracts from animals
    • C12N2500/84Undefined extracts from animals from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/33Insulin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
AT05819135T 2005-11-16 2005-12-20 Aus menschlichem fettgewebe gewonnene multipotente stammzellen und diese enthaltende zelluläre therapeutika ATE510007T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020050109502A KR100679642B1 (ko) 2005-11-16 2005-11-16 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제
PCT/KR2005/004383 WO2007058404A1 (en) 2005-11-16 2005-12-20 Multipotent stem cells derived from human adipose tissue and cellular therapeutic agents comprising the same

Publications (1)

Publication Number Publication Date
ATE510007T1 true ATE510007T1 (de) 2011-06-15

Family

ID=38041072

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05819135T ATE510007T1 (de) 2005-11-16 2005-12-20 Aus menschlichem fettgewebe gewonnene multipotente stammzellen und diese enthaltende zelluläre therapeutika

Country Status (12)

Country Link
US (2) US7807461B2 (de)
EP (1) EP1948786B1 (de)
JP (1) JP4862046B2 (de)
KR (1) KR100679642B1 (de)
CN (1) CN101300343B (de)
AT (1) ATE510007T1 (de)
AU (1) AU2005338370B2 (de)
BR (1) BRPI0520725A2 (de)
DE (1) DE112005003001B4 (de)
GB (1) GB2434801B (de)
RU (1) RU2409665C2 (de)
WO (1) WO2007058404A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100679642B1 (ko) * 2005-11-16 2007-02-06 주식회사 알앤엘바이오 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제
US8592209B2 (en) * 2006-01-30 2013-11-26 University Of Virginia Patent Foundation Methods of preparing and characterizing mesenchymal stem cell aggregates and uses thereof
KR100871984B1 (ko) 2006-04-12 2008-12-05 주식회사 알앤엘바이오 태반 조직 유래 다능성 줄기세포 및 이를 함유하는세포치료제
KR100788632B1 (ko) * 2006-06-15 2007-12-26 주식회사 알앤엘바이오 인간 지방조직 유래 다분화능 줄기세포, 섬유아세포 및지방 또는 지방세포를 함유한 피부미용 또는 성형용조성물의 제조방법
KR100818214B1 (ko) 2006-09-29 2008-04-01 재단법인서울대학교산학협력재단 인간 태반조직의 양막 또는 탈락막 유래 다분화능 줄기세포및 그 제조방법
KR100818216B1 (ko) 2006-10-11 2008-04-01 재단법인서울대학교산학협력재단 Cripto-1 및 Oct4를 동시 발현하는 인간 지방조직 유래 다분화능 줄기세포 또는 종양 줄기세포 및 그 확인방법
US8574567B2 (en) 2007-05-03 2013-11-05 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
EP2607477B1 (de) 2007-05-03 2020-09-23 The Brigham and Women's Hospital, Inc. Multipotente stammzellen und ihre verwendung
KR100895324B1 (ko) * 2007-05-08 2009-05-07 주식회사 휴림바이오셀 성체 줄기세포를 이용한 인슐린 분비세포로의 분화유도방법
JP5509073B2 (ja) 2007-07-12 2014-06-04 ディスクジェニクス ヒト円板組織
KR101046188B1 (ko) * 2007-11-30 2011-07-04 주식회사 알앤엘바이오 탈락막 또는 지방 유래 줄기세포를 함유하는 요실금의 세포치료제
AU2009205886B2 (en) * 2008-01-18 2015-08-27 Katholieke Universiteit Leuven Stem cell aggregates and methods for making and using
GB0805670D0 (en) * 2008-03-28 2008-04-30 Smith & Nephew Increasing the plasticity of stem cells
KR101175175B1 (ko) * 2008-07-28 2012-08-20 서울대학교병원 인간 줄기세포에서 고활성 줄기세포를 분리하는 방법 및상기 방법에 의해 분리된 고활성 줄기 세포
US20100098739A1 (en) * 2008-10-20 2010-04-22 University Of Virginia Patent Foundation Compositions and methods for modular soft tissue repair
US20100112696A1 (en) * 2008-11-03 2010-05-06 Baxter International Inc. Apparatus And Methods For Processing Tissue To Release Cells
US8309343B2 (en) 2008-12-01 2012-11-13 Baxter International Inc. Apparatus and method for processing biological material
WO2010077955A1 (en) * 2008-12-17 2010-07-08 The Scripps Research Institute Generation and maintenance of stem cells
EP2421959A1 (de) * 2009-04-23 2012-02-29 Cytori Therapeutics, Inc. Verwendung von aus fettgewebe stammenden regenerativen zellen bei der modulation einer entzündung in der bauchspeicheldrüse und der niere
US9139812B2 (en) * 2010-02-18 2015-09-22 Kang Stem Holdings Co., Ltd CD49F promoting proliferation, multipotency and reprogramming of adult stem cells through PI3K/AKT/GSK3 pathway
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
KR101211913B1 (ko) * 2010-07-16 2012-12-13 주식회사 알앤엘바이오 양막유래 중간엽 줄기세포 배양을 위한 배지조성물 및 이를 이용한 양막유래 중간엽 줄기세포의 배양방법
EP2609191B1 (de) 2010-08-24 2017-11-22 Regents Of The University Of Minnesota Nichtstatische suspensionskultur aus zellverbänden
AU2011352928B2 (en) 2010-12-27 2017-02-02 Stroma Cell Therapeutics, Llc Ultrasonic cavitation derived stromal or mesenchymal vascular extracts and cells derived therefrom obtained from adipose tissue and use thereof
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
CN104508124B (zh) * 2011-07-06 2017-11-17 细胞治疗有限公司 中胚层谱系祖细胞
KR101138091B1 (ko) * 2011-08-31 2012-04-24 세원셀론텍(주) 중간엽 줄기세포 기본 배양 배지 조성방법, 중간엽 줄기세포 기본 배양 배지 및 이를 이용하여 배양분화된 세포치료제
US20140302480A1 (en) 2011-11-09 2014-10-09 The General Hospital Corporation Composite tissue graft and materials and methods for its production and use
US9708584B2 (en) 2011-12-01 2017-07-18 R Bio Co., Ltd. Medium composition for rejuvenating stem cells
US20150004144A1 (en) 2011-12-02 2015-01-01 The General Hospital Corporation Differentiation into brown adipocytes
US20150044179A1 (en) * 2012-02-24 2015-02-12 Masanori Saeki Cell preparation including fat cell
BR112014025931A2 (pt) * 2012-04-18 2017-07-11 Chan Ra Jeong método para fabricar células-tronco tendo tamanho apropriado para administração intravascular
CN102732480A (zh) * 2012-06-11 2012-10-17 中山大学 N-乙酰半胱氨酸对中央记忆性t细胞的绝对数量在体外扩增上的应用
KR101523040B1 (ko) * 2012-06-26 2015-05-26 라정찬 고농도의 줄기세포 제조방법
CN103845362A (zh) * 2012-12-05 2014-06-11 上海坤爱生物科技有限公司 一种用于治疗糖尿病的干细胞制剂及其制备方法
KR101583569B1 (ko) * 2013-05-15 2016-01-08 라정찬 정맥 투여용 줄기세포 조성물
JP2016519939A (ja) * 2013-05-22 2016-07-11 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California 多能性ヒト脂肪成体幹細胞:単離、キャラクタリゼーションおよび臨床的意味
US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
WO2015105357A1 (ko) * 2014-01-08 2015-07-16 사회복지법인 삼성생명공익재단 영양막 기저층으로부터 유래된 줄기세포 및 이를 포함하는 세포치료제
US20160326487A1 (en) * 2014-01-08 2016-11-10 Samsung Life Public Welfare Foundation Stem Cells Derived from Pure Chorionic Trophoblast Layer and Cell Therapy Comprising Same
ES2754326T3 (es) * 2014-01-31 2020-04-17 Dsm Ip Assets Bv Centrifugadora de tejido adiposo y procedimiento de uso
KR101496804B1 (ko) * 2014-06-12 2015-03-02 서울대학교산학협력단 인슐린 생산세포로의 분화 및 이용방법
TWI707040B (zh) * 2014-09-11 2020-10-11 台灣粒線體應用技術股份有限公司 一種用於治療退化性神經疾病的細胞、含有該細胞的醫藥組合物及其應用
US10287551B2 (en) 2014-10-29 2019-05-14 R Bio Co., Ltd. Medium composition for culturing stem cells
CN104673745A (zh) * 2015-02-05 2015-06-03 广州赛莱拉干细胞科技股份有限公司 一种猪脂肪干细胞的分离培养方法
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
JP6714932B2 (ja) * 2015-12-01 2020-07-01 株式会社AdipoSeeds 脊椎動物の脂肪組織由来間葉系細胞株の製造方法
US10513689B2 (en) 2016-04-29 2019-12-24 Hope Biosciences, Llc Culture media for multipotent stem cells
US10959425B2 (en) 2016-04-29 2021-03-30 Hope Biosciences, Llc Method of banking stem cells
US10988731B2 (en) 2016-04-29 2021-04-27 Hope Biosciences, Llc Formulation for storage, transportation, and delivery of protein rich conditioned medium
US10894947B1 (en) 2016-04-29 2021-01-19 Hope Biosciences, Llc Method for generating protein rich conditioned medium
US11111480B2 (en) 2016-04-29 2021-09-07 Hope Biosctences, Llc Culture media for multipotent stem cells
CN106047804B (zh) * 2016-05-30 2019-11-12 浙江大学 一种脂肪干细胞的纯化方法及干细胞在成骨诱导及成软骨诱导上的应用
RU2653779C1 (ru) * 2016-12-26 2018-05-14 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ стимуляции сперматогенеза
RU2652902C1 (ru) * 2016-12-26 2018-05-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ стимуляции сперматогенеза
CN108690828A (zh) * 2017-04-12 2018-10-23 上海聚仁生物科技有限公司 一种脂肪多能细胞的分离及其培养方法
USD848022S1 (en) 2017-07-14 2019-05-07 Hope Biosciences, Llc Container for storing biological material
USD875967S1 (en) 2017-07-14 2020-02-18 Hope Biosciences, Llc Container for storing biological material
KR20190011213A (ko) 2017-07-24 2019-02-01 한양대학교 에리카산학협력단 줄기세포로부터 추출된 엑소좀을 유효성분으로 포함하는 골다공증 예방 또는 치료용 조성물
WO2019022451A2 (ko) 2017-07-24 2019-01-31 한양대학교 에리카산학협력단 줄기세포로부터 추출된 엑소좀을 유효성분으로 포함하는 골다공증 예방 또는 치료용 조성물
WO2020007878A1 (en) * 2018-07-03 2020-01-09 Universidad Del País Vasco - Euskal Herriko Unibertsitatea Cellular aggregates for use in vascularisation therapy
CN111218423A (zh) * 2018-11-26 2020-06-02 上海泉眼生物科技有限公司 脂肪干细胞来源的神经元前体细胞及其制备方法和应用
US11674131B2 (en) 2018-12-03 2023-06-13 Ross Ward Indirect ultrasonic cavitation-derived perivascular cells and methods of use thereof
WO2020165152A1 (en) * 2019-02-13 2020-08-20 Tigenix, S.A.U. Cryopreservation of stem cells
TWI832070B (zh) * 2021-07-15 2024-02-11 國璽幹細胞應用技術股份有限公司 幹細胞製劑用於治療關節炎的用途及用於製備幹細胞製劑的方法
KR102819184B1 (ko) * 2022-05-26 2025-06-13 주식회사 셀진 하이드로겔 및 줄기세포 스페로이드를 포함하는 골 재생용 조성물 및 이의 용도
CN116076484A (zh) * 2022-11-30 2023-05-09 武汉大学 一种修复肾脏损伤的低温携氧机械灌注液及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777231B1 (en) 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
KR100979664B1 (ko) * 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
EP1261694B1 (de) 2000-02-26 2008-01-16 Artecel, Inc. Pluripotente stammzellen erzeugt aus stromalzellen aus dem fettgewebe und deren verwendungen
FR2815042B1 (fr) 2000-10-06 2005-01-07 Haguenauer Odile Cohen Utilisation d'une composition a activite antioxydante pour le conditionnement de cellules souches
KR20040094910A (ko) * 2002-04-03 2004-11-10 아르테셀 사이언스, 인크. 개선된 지방세포 분화된 지방 유래 성체 줄기세포 및 이의용도
US20060258003A1 (en) * 2002-12-13 2006-11-16 Celogos Culture medium composition, culture method, and myoblasts obtained, and their uses
WO2005085422A1 (en) * 2004-02-27 2005-09-15 Michigan State University Adult stem cells and uses thereof
JP2005287479A (ja) * 2004-03-31 2005-10-20 Kazuhisa Maeda 組織幹細胞採取方法及びそれを利用した装置
RU2252252C1 (ru) * 2004-04-09 2005-05-20 Тепляшин Александр Сергеевич Способ выделения мезенхимальных стволовых клеток
KR100679642B1 (ko) * 2005-11-16 2007-02-06 주식회사 알앤엘바이오 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제

Also Published As

Publication number Publication date
GB2434801A (en) 2007-08-08
CN101300343A (zh) 2008-11-05
EP1948786A4 (de) 2008-11-26
RU2409665C2 (ru) 2011-01-20
US20070110729A1 (en) 2007-05-17
DE112005003001B4 (de) 2009-03-19
KR100679642B1 (ko) 2007-02-06
EP1948786A1 (de) 2008-07-30
US7807461B2 (en) 2010-10-05
BRPI0520725A2 (pt) 2010-08-17
WO2007058404A1 (en) 2007-05-24
DE112005003001T5 (de) 2007-10-18
JP2009527221A (ja) 2009-07-30
CN101300343B (zh) 2011-06-22
AU2005338370B2 (en) 2011-06-09
RU2008116175A (ru) 2009-10-27
US20110171726A1 (en) 2011-07-14
GB0706021D0 (en) 2007-05-09
EP1948786B1 (de) 2011-05-18
JP4862046B2 (ja) 2012-01-25
AU2005338370A1 (en) 2007-05-24
GB2434801B (en) 2011-04-27

Similar Documents

Publication Publication Date Title
ATE510007T1 (de) Aus menschlichem fettgewebe gewonnene multipotente stammzellen und diese enthaltende zelluläre therapeutika
Lopa et al. Donor-matched mesenchymal stem cells from knee infrapatellar and subcutaneous adipose tissue of osteoarthritic donors display differential chondrogenic and osteogenic commitment
WO2008013863A3 (en) Generation of adipose tissue and adipocytes
NZ591626A (en) Therapeutic methods using adipose tissue-derived cell suspensions comprising adipocytes
HRP20250245T1 (hr) Pluripotentna matična stanica koja se može izolirati iz tjelesnog tkiva
Heino et al. Comparison of the osteogenic capacity of minipig and human bone marrow‐derived mesenchymal stem cells
WO2009098698A3 (en) Compartmental extract compositions for tissue engineering
WO2010059565A3 (en) Allografts combined with tissue derived stem cells for bone healing
ITRM20050265A1 (it) Protesi modulare perfezionata per osteosintesi, in particolare per l'osteosintesi dell'omero.
WO2009134532A3 (en) Homing in mesenchymal stem cells
WO2007080590A3 (en) Human embryonic stem cell-derived connective tissue progenitors for tissue engineering
EP1855721A4 (de) Verfahren und zusammensetzung zur behandlung von säugetier-krankheiten und verletzungen durch überexpression von peroxynitrit
IL189164A0 (en) Pyrimidine compounds as serotonin receptor modulators
MX342475B (es) Componente del tibial.
TW200637865A (en) Processes for preparing pyrazolo[3,4-d]pyrimidine ethers
Guneta et al. Comparative study of adipose-derived stem cells from abdomen and breast
MX345409B (es) Composiciones bioactivas que comprenden fraccion de suero de ficus y metodos para reducir la aparicion de hiperpigmentacion de la piel.
Krattinger et al. Regulation of proliferation and differentiation of human fetal bone cells
Kassem et al. Association of expression levels of pluripotency/stem cell markers with the differentiation outcome of Wharton's jelly mesenchymal stem cells into insulin producing cells
WO2013176538A3 (en) Tenogenic medium for mesenchymal stem cells differentation into tenogenic lineage
Melzer et al. Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells
DE602005017812D1 (de) Multipotente blutstammzellen aus der nabelschnur und zellbehandlungsmittel damit zur behandlung der ischämischen krankheit
Malik et al. Generation of handmade cloned embryos from adipose tissue derived mesenchymal stem cells in goat
Silva et al. Expression of pancreatic endocrine markers by mesenchymal stem cells from human adipose tissue
PT1890713E (pt) Composição de osteoblastos de fibrina mista semisolidificada para aglutinação de fractura óssea e seu método de produção

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties