ATE510822T1 - Kaliumkanalinhibitoren - Google Patents
KaliumkanalinhibitorenInfo
- Publication number
- ATE510822T1 ATE510822T1 AT06816997T AT06816997T ATE510822T1 AT E510822 T1 ATE510822 T1 AT E510822T1 AT 06816997 T AT06816997 T AT 06816997T AT 06816997 T AT06816997 T AT 06816997T AT E510822 T1 ATE510822 T1 AT E510822T1
- Authority
- AT
- Austria
- Prior art keywords
- potassium channel
- channel inhibitors
- inhibitors
- compounds
- relates
- Prior art date
Links
- 102000004257 Potassium Channel Human genes 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 108020001213 potassium channel Proteins 0.000 title abstract 2
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Magnetic Heads (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72907805P | 2005-10-21 | 2005-10-21 | |
| PCT/US2006/040409 WO2007050347A1 (en) | 2005-10-21 | 2006-10-17 | Potassium channel inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE510822T1 true ATE510822T1 (de) | 2011-06-15 |
Family
ID=37845325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06816997T ATE510822T1 (de) | 2005-10-21 | 2006-10-17 | Kaliumkanalinhibitoren |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7973059B2 (de) |
| EP (1) | EP1951672B1 (de) |
| JP (1) | JP4931930B2 (de) |
| KR (1) | KR20080057296A (de) |
| CN (1) | CN101291910A (de) |
| AT (1) | ATE510822T1 (de) |
| AU (1) | AU2006306541B2 (de) |
| BR (1) | BRPI0617655A2 (de) |
| CA (1) | CA2626402C (de) |
| IL (1) | IL190730A0 (de) |
| NO (1) | NO20082298L (de) |
| NZ (1) | NZ567000A (de) |
| RU (1) | RU2008119994A (de) |
| WO (1) | WO2007050347A1 (de) |
| ZA (1) | ZA200802848B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2750359T3 (es) * | 2009-03-18 | 2020-03-25 | Incarda Therapeutics Inc | Dosis unitarias, aerosoles, kits y procedimientos para tratar afecciones cardíacas mediante administración pulmonar |
| US20130102477A1 (en) | 2010-06-23 | 2013-04-25 | Ryan D. Morin | Biomarkers for non-hodgkin lymphomas and uses thereof |
| AU2011298987B2 (en) | 2010-09-10 | 2017-09-28 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
| US9175331B2 (en) | 2010-09-10 | 2015-11-03 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
| JO3363B1 (ar) | 2011-04-13 | 2019-03-13 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
| TW201733984A (zh) | 2011-04-13 | 2017-10-01 | 雅酶股份有限公司 | 經取代之苯化合物 |
| DK3628670T3 (da) | 2012-04-13 | 2022-12-05 | Epizyme Inc | Saltform til ezh2-hæmning |
| CN105102432B (zh) | 2012-10-15 | 2019-01-04 | Epizyme股份有限公司 | 经取代的苯化合物 |
| EP3057962B1 (de) | 2013-10-16 | 2023-10-18 | Epizyme, Inc. | Hydrochloridsalzform zur ezh2-hemmung |
| MY186839A (en) | 2014-06-19 | 2021-08-25 | Takeda Pharmaceuticals Co | Heteroaryl compounds for kinase inhibition |
| IL260335B2 (en) | 2016-02-01 | 2023-10-01 | Incarda Therapeutics Inc | Combining electronic monitoring with inhaled pharmacological therapy for the management of cardiac arrhythmia including atrial fibrillation |
| JP2020519628A (ja) | 2017-05-10 | 2020-07-02 | インカーダ セラピューティクス， インコーポレイテッド | 肺投与によって心臓の状態を処置するための単位用量、エアロゾル、キットおよび方法 |
| ES3040411T3 (en) | 2018-03-22 | 2025-10-30 | Incarda Therapeutics Inc | A novel method to slow ventricular rate |
| EP4234547A3 (de) | 2018-05-14 | 2023-11-01 | Takeda Pharmaceutical Company Limited | Pharmazeutische salze von pyrimidinderivaten und verfahren zur behandlung von störungen |
| IL321589A (en) | 2019-08-01 | 2025-08-01 | Incarda Therapeutics Inc | Antiarrhythmic formulation comprising a salt of flecainide |
| US11020384B2 (en) | 2019-08-01 | 2021-06-01 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4719744B2 (ja) * | 2004-07-29 | 2011-07-06 | メルク・シャープ・エンド・ドーム・コーポレイション | カリウムチャンネル阻害剤 |
| CA2575003C (en) * | 2004-07-29 | 2010-02-16 | Merck & Co., Inc. | Potassium channel inhibitors |
| US8148535B2 (en) * | 2005-10-21 | 2012-04-03 | Merck Sharp & Dohme Corp. | Potassium channel inhibitors |
-
2006
- 2006-10-17 EP EP06816997A patent/EP1951672B1/de not_active Not-in-force
- 2006-10-17 JP JP2008536717A patent/JP4931930B2/ja not_active Expired - Fee Related
- 2006-10-17 KR KR1020087009300A patent/KR20080057296A/ko not_active Withdrawn
- 2006-10-17 AT AT06816997T patent/ATE510822T1/de not_active IP Right Cessation
- 2006-10-17 AU AU2006306541A patent/AU2006306541B2/en not_active Ceased
- 2006-10-17 CN CNA2006800388932A patent/CN101291910A/zh active Pending
- 2006-10-17 CA CA2626402A patent/CA2626402C/en not_active Expired - Fee Related
- 2006-10-17 WO PCT/US2006/040409 patent/WO2007050347A1/en not_active Ceased
- 2006-10-17 RU RU2008119994/04A patent/RU2008119994A/ru not_active Application Discontinuation
- 2006-10-17 BR BRPI0617655A patent/BRPI0617655A2/pt not_active IP Right Cessation
- 2006-10-17 NZ NZ567000A patent/NZ567000A/en unknown
- 2006-10-17 US US11/992,919 patent/US7973059B2/en active Active
-
2008
- 2008-04-01 ZA ZA200802848A patent/ZA200802848B/xx unknown
- 2008-04-08 IL IL190730A patent/IL190730A0/en unknown
- 2008-05-20 NO NO20082298A patent/NO20082298L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL190730A0 (en) | 2008-11-03 |
| EP1951672B1 (de) | 2011-05-25 |
| US7973059B2 (en) | 2011-07-05 |
| JP4931930B2 (ja) | 2012-05-16 |
| JP2009512702A (ja) | 2009-03-26 |
| ZA200802848B (en) | 2009-01-28 |
| AU2006306541B2 (en) | 2011-07-14 |
| CA2626402C (en) | 2011-02-15 |
| EP1951672A1 (de) | 2008-08-06 |
| AU2006306541A1 (en) | 2007-05-03 |
| WO2007050347A1 (en) | 2007-05-03 |
| CA2626402A1 (en) | 2007-05-03 |
| NZ567000A (en) | 2010-03-26 |
| BRPI0617655A2 (pt) | 2016-08-23 |
| NO20082298L (no) | 2008-07-17 |
| US20090042944A1 (en) | 2009-02-12 |
| KR20080057296A (ko) | 2008-06-24 |
| RU2008119994A (ru) | 2009-12-10 |
| CN101291910A (zh) | 2008-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |