ATE510929T1 - Verfahren zur vorhersage einer immunantwort auf eine tumorerkrankung auf der grundlage eines mrna-expressionsprofils in tumorzellen und stimulierten leukozyten - Google Patents
Verfahren zur vorhersage einer immunantwort auf eine tumorerkrankung auf der grundlage eines mrna-expressionsprofils in tumorzellen und stimulierten leukozytenInfo
- Publication number
- ATE510929T1 ATE510929T1 AT06772657T AT06772657T ATE510929T1 AT E510929 T1 ATE510929 T1 AT E510929T1 AT 06772657 T AT06772657 T AT 06772657T AT 06772657 T AT06772657 T AT 06772657T AT E510929 T1 ATE510929 T1 AT E510929T1
- Authority
- AT
- Austria
- Prior art keywords
- tnf
- cancer
- leukocytes
- chemokines
- immune response
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68874405P | 2005-06-08 | 2005-06-08 | |
| US73550805P | 2005-11-11 | 2005-11-11 | |
| PCT/US2006/022427 WO2006133399A1 (en) | 2005-06-08 | 2006-06-08 | METHOD FOR PREDICTING IMMUNE RESPONSE TO NEOPLASTIC DISEASE BASED ON mRNA EXPRESSION PROFILE IN NEOPLASTIC CELLS AND STIMULATED LEUKOCYTES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE510929T1 true ATE510929T1 (de) | 2011-06-15 |
Family
ID=37498782
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08008370T ATE493515T1 (de) | 2005-06-08 | 2006-06-08 | Verfahren zur vorhersage der immunreaktion auf neoplastische krankheiten auf der grundlage des mrna-ausdrucksprofil in neoplastischen zellen und stimulierten leukozyten |
| AT06772657T ATE510929T1 (de) | 2005-06-08 | 2006-06-08 | Verfahren zur vorhersage einer immunantwort auf eine tumorerkrankung auf der grundlage eines mrna-expressionsprofils in tumorzellen und stimulierten leukozyten |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08008370T ATE493515T1 (de) | 2005-06-08 | 2006-06-08 | Verfahren zur vorhersage der immunreaktion auf neoplastische krankheiten auf der grundlage des mrna-ausdrucksprofil in neoplastischen zellen und stimulierten leukozyten |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7741023B2 (de) |
| EP (2) | EP1904657B1 (de) |
| JP (1) | JP4800384B2 (de) |
| CN (1) | CN101194027B (de) |
| AT (2) | ATE493515T1 (de) |
| DE (1) | DE602006019312D1 (de) |
| WO (1) | WO2006133399A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008503206A (ja) * | 2004-05-25 | 2008-02-07 | 日立化成工業株式会社 | 癌感受性を測定する方法 |
| CN101044249B (zh) * | 2004-10-20 | 2012-09-05 | 日立化成工业株式会社 | 通过定量mRNA定制给药的方法 |
| ATE512234T1 (de) * | 2005-04-28 | 2011-06-15 | Hitachi Chemical Res Ct Inc | Ex-vivo-genexpression in vollblut als modell für die beurteilung von individueller variation gegenüber nahrungszusätzen |
| DE102007045562A1 (de) * | 2007-09-24 | 2009-04-02 | Robert Bosch Gmbh | Steuereinrichtung für eine Anzeigeeinrichtung einer Einparkeinrichtung und Verfahren zur Darstellung |
| JP2011502535A (ja) * | 2007-11-14 | 2011-01-27 | 日立化成工業株式会社 | 末梢血白血球における、Fc受容体を介した腫瘍壊死因子スーパーファミリーmRNA発現 |
| NZ598712A (en) * | 2009-08-28 | 2014-05-30 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011084333A1 (en) * | 2009-12-16 | 2011-07-14 | Hitachi Chemical Co., Ltd. | Method for characterizing host immune function by ex vivo induction of offensive and defensive immune markers |
| CN102947706B (zh) | 2010-04-19 | 2018-04-13 | 生物标志物策略公司 | 预测药物敏感性、抗性和疾病进展的组合物和方法 |
| WO2012007783A1 (en) * | 2010-07-13 | 2012-01-19 | Institut Gustave Roussy | Kits and methods for detecting the ability to induce an immunogenic cancer cell death in a subject |
| US8828944B2 (en) | 2010-04-22 | 2014-09-09 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| WO2011131246A1 (en) * | 2010-04-22 | 2011-10-27 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| US8865653B2 (en) | 2010-04-22 | 2014-10-21 | Institut Gustave Roussy | Method of treatment for immunogenic treatment resistant cancer |
| WO2011140125A1 (en) | 2010-05-07 | 2011-11-10 | Hitachi Chemical Co., Ltd. | Methods of characterizing host responsiveness to interferon by ex vivo induction of interferon-responsive markers |
| EP2388312A1 (de) | 2010-05-17 | 2011-11-23 | Curetis AG | Universell anwendbarer Lysepuffer und Verarbeitungsverfahren zur Lyse von Körperproben |
| WO2011156763A1 (en) | 2010-06-11 | 2011-12-15 | Hitachi Chemical Co., Ltd. | Methods for characterizing kidney function |
| WO2011156734A2 (en) * | 2010-06-11 | 2011-12-15 | Hitachi Chemical Co., Ltd. | Method of characterizing vascular diseases |
| JP5823031B2 (ja) | 2011-06-10 | 2015-11-25 | 日立化成株式会社 | 小胞捕捉デバイスおよびそれを用いるための方法 |
| EP2734233B1 (de) * | 2011-07-18 | 2017-11-01 | Hitachi Chemical Co., Ltd. | Verfahren zur vorhersage des ansprechens eines wirtes auf krebsimmuntherapien durch ex-vivo-induktion von mit leukozytenfunktionen assoziierten mrnas |
| EP2751570A4 (de) * | 2011-08-31 | 2015-08-12 | Oncocyte Corp | Verfahren und zusammensetzungen zur behandlung und diagnose von krebs |
| JP6059350B2 (ja) * | 2012-09-06 | 2017-01-11 | 日立化成株式会社 | ペプチド特異的免疫の評価のための方法 |
| JP2014057582A (ja) * | 2012-09-17 | 2014-04-03 | Hitachi Chemical Co Ltd | 細胞傷害活性を予測するための方法及びキット |
| CN103193886A (zh) * | 2013-04-14 | 2013-07-10 | 浙江大学 | 鼠抗人T细胞抗原ZCH-2B8a荧光标记单抗的用途 |
| WO2014182330A1 (en) | 2013-05-06 | 2014-11-13 | Hitachi Chemical Company Ltd | Devices and methods for capturing target molecules |
| WO2016048388A1 (en) | 2014-09-26 | 2016-03-31 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
| US10266895B2 (en) | 2014-11-05 | 2019-04-23 | Hitachi Chemical Company Ltd. | Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease |
| EP3218521B1 (de) | 2014-11-12 | 2019-12-25 | Hitachi Chemical Co., Ltd. | Verfahren zur diagnose von organverletzung |
| DE112016003948T5 (de) | 2015-08-31 | 2018-05-09 | City Of Sapporo | Molekulare verfahren zum beurteilen einer urothelialen erkrankung |
| AU2017261353A1 (en) * | 2016-05-05 | 2018-11-08 | Nantomics, Llc | Checkpoint failure and methods therefor |
| CN110073221A (zh) * | 2016-10-14 | 2019-07-30 | 思迪奇细胞私人有限公司 | 白细胞粘附功能测定、设备和/或用途 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4925572A (en) * | 1987-10-20 | 1990-05-15 | Pall Corporation | Device and method for depletion of the leukocyte content of blood and blood components |
| US4880548A (en) * | 1988-02-17 | 1989-11-14 | Pall Corporation | Device and method for separating leucocytes from platelet concentrate |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5491063A (en) * | 1994-09-01 | 1996-02-13 | Hoffmann-La Roche Inc. | Methods for in-solution quenching of fluorescently labeled oligonucleotide probes |
| DE69739909D1 (de) * | 1996-03-26 | 2010-07-29 | Michael S Kopreski | Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden |
| US5683698A (en) * | 1996-08-02 | 1997-11-04 | New England Deaconess Hospital | Formulation for alleviating symptoms associated with arthritis |
| US7514232B2 (en) * | 1996-12-06 | 2009-04-07 | Becton, Dickinson And Company | Method for detecting T cell response to specific antigens in whole blood |
| US6183951B1 (en) | 1997-04-11 | 2001-02-06 | Prometheus Laboratories, Inc. | Methods of diagnosing clinical subtypes of crohn's disease with characteristic responsiveness to anti-Th1 cytokine therapy |
| US20020006613A1 (en) * | 1998-01-20 | 2002-01-17 | Shyjan Andrew W. | Methods and compositions for the identification and assessment of cancer therapies |
| AU768189B2 (en) | 1999-06-15 | 2003-12-04 | Nutri-Logics, Inc. | Nutrient formulations for disease reduction, and related treatment and component screening methods |
| US6692916B2 (en) * | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US6549616B1 (en) * | 2000-03-20 | 2003-04-15 | Serconet Ltd. | Telephone outlet for implementing a local area network over telephone lines and a local area network using such outlets |
| US20020048566A1 (en) * | 2000-09-14 | 2002-04-25 | El-Deiry Wafik S. | Modulation of cellular apoptosis and methods for treating cancer |
| US20020182274A1 (en) | 2001-03-21 | 2002-12-05 | Kung-Ming Lu | Methods for inhibiting cancer growth, reducing infection and promoting general health with a fermented soy extract |
| US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US6964850B2 (en) | 2001-11-09 | 2005-11-15 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US7767390B2 (en) * | 2001-11-20 | 2010-08-03 | Oncomedx, Inc. | Methods for evaluating drug-resistance gene expression in the cancer patient |
| US7871619B2 (en) | 2001-11-30 | 2011-01-18 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| FI20020078A7 (fi) | 2002-01-15 | 2003-07-16 | Danisco | Immuunijärjestelmän stimulointi polydextroosilla |
| US6878518B2 (en) * | 2002-01-22 | 2005-04-12 | The Trustees Of The University Of Pennsylvania | Methods for determining steroid responsiveness |
| US7745180B2 (en) * | 2002-04-24 | 2010-06-29 | Hitachi Chemical Co., Ltd. | Device and method for high-throughput quantification of mRNA from whole blood |
| AU2003232872A1 (en) | 2002-05-27 | 2003-12-12 | Ostergotlands Lans Landsting | Method for determining immune system affecting compounds |
| AU2002953533A0 (en) * | 2002-12-24 | 2003-01-16 | Arthron Limited | Fc receptor modulating compounds and compositions |
| JP2008503206A (ja) * | 2004-05-25 | 2008-02-07 | 日立化成工業株式会社 | 癌感受性を測定する方法 |
| EP1875246B1 (de) | 2005-04-15 | 2016-10-05 | CanImGuide Therapeutics AB | Diagnoseverfahren zum nachweis von krebs durch messen der menge eines cytokinähnlichen il-6 |
| ATE512234T1 (de) * | 2005-04-28 | 2011-06-15 | Hitachi Chemical Res Ct Inc | Ex-vivo-genexpression in vollblut als modell für die beurteilung von individueller variation gegenüber nahrungszusätzen |
| EP1945814A2 (de) | 2005-09-27 | 2008-07-23 | Source MDX | Erstellung von genexpressionsprofilen zur identifizierung , beobachtung und behandlung rheumatoider arthritis |
| US20100190162A1 (en) | 2007-02-26 | 2010-07-29 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
-
2006
- 2006-06-08 JP JP2008515958A patent/JP4800384B2/ja not_active Expired - Fee Related
- 2006-06-08 EP EP06772657A patent/EP1904657B1/de not_active Not-in-force
- 2006-06-08 AT AT08008370T patent/ATE493515T1/de not_active IP Right Cessation
- 2006-06-08 US US11/917,151 patent/US7741023B2/en not_active Expired - Fee Related
- 2006-06-08 WO PCT/US2006/022427 patent/WO2006133399A1/en not_active Ceased
- 2006-06-08 AT AT06772657T patent/ATE510929T1/de not_active IP Right Cessation
- 2006-06-08 EP EP08008370A patent/EP1964931B1/de not_active Not-in-force
- 2006-06-08 CN CN2006800202986A patent/CN101194027B/zh not_active Expired - Fee Related
- 2006-06-08 DE DE602006019312T patent/DE602006019312D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN101194027B (zh) | 2012-10-24 |
| WO2006133399A1 (en) | 2006-12-14 |
| ATE493515T1 (de) | 2011-01-15 |
| JP4800384B2 (ja) | 2011-10-26 |
| US7741023B2 (en) | 2010-06-22 |
| WO2006133399A9 (en) | 2007-03-01 |
| EP1964931A3 (de) | 2009-01-21 |
| DE602006019312D1 (de) | 2011-02-10 |
| EP1904657A1 (de) | 2008-04-02 |
| JP2008543286A (ja) | 2008-12-04 |
| EP1964931B1 (de) | 2010-12-29 |
| EP1904657B1 (de) | 2011-05-25 |
| US20090111128A1 (en) | 2009-04-30 |
| EP1904657A4 (de) | 2008-12-31 |
| EP1964931A2 (de) | 2008-09-03 |
| CN101194027A (zh) | 2008-06-04 |
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| Date | Code | Title | Description |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |