ATE512159T1 - Cyclodipeptidsynthetasen und ihre verwendung zur synthese von cyclo(leu-leu)cyclodipeptid - Google Patents
Cyclodipeptidsynthetasen und ihre verwendung zur synthese von cyclo(leu-leu)cyclodipeptidInfo
- Publication number
- ATE512159T1 ATE512159T1 AT06755971T AT06755971T ATE512159T1 AT E512159 T1 ATE512159 T1 AT E512159T1 AT 06755971 T AT06755971 T AT 06755971T AT 06755971 T AT06755971 T AT 06755971T AT E512159 T1 ATE512159 T1 AT E512159T1
- Authority
- AT
- Austria
- Prior art keywords
- leu
- cyclodipeptide
- polynucleotides
- cyclo
- synthesis
- Prior art date
Links
- XWYXUMDVQIOAPR-UHFFFAOYSA-N (3S,6S)-3,6-Diisobutyl-2,5-dioxohexahydropyrazine Natural products CC(C)CC1NC(=O)C(CC(C)C)NC1=O XWYXUMDVQIOAPR-UHFFFAOYSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- XWYXUMDVQIOAPR-UWVGGRQHSA-N cyclo(L-leucyl-L-leucyl) Chemical compound CC(C)C[C@@H]1NC(=O)[C@H](CC(C)C)NC1=O XWYXUMDVQIOAPR-UWVGGRQHSA-N 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 102000003960 Ligases Human genes 0.000 title 1
- 108090000364 Ligases Proteins 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 abstract 5
- 108091033319 polynucleotide Proteins 0.000 abstract 5
- 239000002157 polynucleotide Substances 0.000 abstract 5
- 239000013598 vector Substances 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2006/001849 WO2007122446A1 (en) | 2006-04-26 | 2006-04-26 | Cyclodipeptide synthetases and their use for synthesis of cyclo(leu-leu) cyclodipeptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE512159T1 true ATE512159T1 (de) | 2011-06-15 |
Family
ID=37564407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06755971T ATE512159T1 (de) | 2006-04-26 | 2006-04-26 | Cyclodipeptidsynthetasen und ihre verwendung zur synthese von cyclo(leu-leu)cyclodipeptid |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090264616A1 (de) |
| EP (1) | EP2021357B1 (de) |
| JP (1) | JP2009534048A (de) |
| AT (1) | ATE512159T1 (de) |
| WO (1) | WO2007122446A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7476516B2 (en) | 2002-07-26 | 2009-01-13 | Novozymes, Inc. | Methods for producing biological substances in pigment-deficient mutants of Bacillus cells |
| EP2212419A1 (de) * | 2007-10-31 | 2010-08-04 | Kyowa Hakko Bio Co., Ltd. | Cyclodipeptid-synthasen (cdss) und deren verwendung bei der synthese linearer dipeptide |
| CN103130809B (zh) * | 2013-01-30 | 2016-03-09 | 青岛农业大学 | 桑黄菌中六氢-7-羟基-3-(2-甲基丙基)吡咯并[1,2-a]吡嗪-1,4-二酮的分离技术 |
| CN103145716B (zh) * | 2013-01-30 | 2016-03-30 | 青岛农业大学 | 桑黄菌中环二肽c6的高压反相制备分离技术 |
| CN109824757B (zh) * | 2019-02-15 | 2020-12-25 | 山东蓬勃生物科技有限公司 | 一种环(异亮-异亮)二肽、其制备方法及其应用 |
| CN119799825B (zh) * | 2024-12-23 | 2026-03-13 | 山东蓬勃生物科技有限公司 | 环(异亮-异亮)二肽的制备方法及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4006261A (en) * | 1973-09-28 | 1977-02-01 | Firmenich S.A. | Flavoring with mixtures of theobromine and cyclic dipeptides |
| FR2841260B1 (fr) * | 2002-06-21 | 2004-10-22 | Commissariat Energie Atomique | Polynucleotides et polypeptides codes par lesdits polynucleotides impliques dans la synthese de derives des dicetopiperazines |
| US7476516B2 (en) * | 2002-07-26 | 2009-01-13 | Novozymes, Inc. | Methods for producing biological substances in pigment-deficient mutants of Bacillus cells |
| US20070243581A1 (en) * | 2004-04-21 | 2007-10-18 | Hashimoto Shin-Ichi | Process for Producing Dipeptides |
| DE102004061664A1 (de) * | 2004-12-22 | 2006-07-06 | Henkel Kgaa | Nukleinsäure-bindende Chips zur Detektion von Phosphatmangelzuständen im Rahmen der Bioprozesskontrolle |
-
2006
- 2006-04-26 WO PCT/IB2006/001849 patent/WO2007122446A1/en not_active Ceased
- 2006-04-26 AT AT06755971T patent/ATE512159T1/de not_active IP Right Cessation
- 2006-04-26 EP EP06755971A patent/EP2021357B1/de not_active Not-in-force
- 2006-04-26 US US12/226,661 patent/US20090264616A1/en not_active Abandoned
- 2006-04-26 JP JP2009507185A patent/JP2009534048A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007122446A1 (en) | 2007-11-01 |
| EP2021357A1 (de) | 2009-02-11 |
| US20090264616A1 (en) | 2009-10-22 |
| JP2009534048A (ja) | 2009-09-24 |
| EP2021357B1 (de) | 2011-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |