ATE512365T1 - Map-2 proteolytische produkte als diagnostische biomarker fur neuralen verletzungen - Google Patents
Map-2 proteolytische produkte als diagnostische biomarker fur neuralen verletzungenInfo
- Publication number
- ATE512365T1 ATE512365T1 AT05779948T AT05779948T ATE512365T1 AT E512365 T1 ATE512365 T1 AT E512365T1 AT 05779948 T AT05779948 T AT 05779948T AT 05779948 T AT05779948 T AT 05779948T AT E512365 T1 ATE512365 T1 AT E512365T1
- Authority
- AT
- Austria
- Prior art keywords
- injury
- map
- neural injury
- diagnostic biomarkers
- proteolytic products
- Prior art date
Links
- 208000027418 Wounds and injury Diseases 0.000 title abstract 4
- 230000006378 damage Effects 0.000 title abstract 4
- 208000014674 injury Diseases 0.000 title abstract 4
- 230000001537 neural effect Effects 0.000 title abstract 2
- 108090000192 Methionyl aminopeptidases Proteins 0.000 title 1
- 102100021118 Microtubule-associated protein 2 Human genes 0.000 title 1
- 239000000104 diagnostic biomarker Substances 0.000 title 1
- 230000002797 proteolythic effect Effects 0.000 title 1
- 239000000090 biomarker Substances 0.000 abstract 2
- 208000028389 Nerve injury Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000005779 cell damage Effects 0.000 abstract 1
- 208000037887 cell injury Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000008764 nerve damage Effects 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000004960 subcellular localization Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
- Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56281904P | 2004-04-15 | 2004-04-15 | |
| PCT/US2005/013045 WO2005113798A2 (en) | 2004-04-15 | 2005-04-15 | Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE512365T1 true ATE512365T1 (de) | 2011-06-15 |
Family
ID=35428934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05779948T ATE512365T1 (de) | 2004-04-15 | 2005-04-15 | Map-2 proteolytische produkte als diagnostische biomarker fur neuralen verletzungen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7456027B2 (de) |
| EP (1) | EP1747282B1 (de) |
| JP (1) | JP4885122B2 (de) |
| AT (1) | ATE512365T1 (de) |
| AU (1) | AU2005245785B2 (de) |
| CA (1) | CA2578680C (de) |
| ES (1) | ES2367311T3 (de) |
| WO (1) | WO2005113798A2 (de) |
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| US6589746B1 (en) * | 1999-10-21 | 2003-07-08 | University Of Cincinnati | Method of detecting axonally-derived protein tau in patients with traumatic CNS injury |
| US6819325B2 (en) * | 2000-03-07 | 2004-11-16 | Microsoft Corporation | API communications for vertex and pixel shaders |
| US20030040660A1 (en) * | 2001-08-27 | 2003-02-27 | George Jackowski | Method for diagnosing and distinguishing traumatic brain injury and diagnostic devices for use therein |
| JP2005538380A (ja) * | 2002-09-11 | 2005-12-15 | ユニヴァーシティ オヴ フロリダ | 神経細胞損傷の分析 |
| US7196169B2 (en) * | 2002-10-11 | 2007-03-27 | Queen's University At Kingston | Isolated post-translationally modified mammalian proteins for monitoring and diagnosing muscle damage |
| US20040241762A1 (en) * | 2003-03-31 | 2004-12-02 | Gerry Shaw | Assessing neuronal damage from blood samples |
| US20050202508A1 (en) * | 2003-11-12 | 2005-09-15 | Pasinetti Guilio M. | Biomarker for Parkinson's disease |
| EP1745149A4 (de) * | 2004-04-15 | 2008-08-06 | Univ Florida | Neurale proteine als biomarker für eine verletzung des nervensystems und andere neurale störungen |
| ES2732071T3 (es) | 2005-04-01 | 2019-11-20 | Univ Florida | Biomarcadores de lesiones hepáticas |
| US7398484B2 (en) * | 2005-04-27 | 2008-07-08 | Microsoft Corporation | Memory efficient array transposition via multi pass tiling |
-
2005
- 2005-04-15 WO PCT/US2005/013045 patent/WO2005113798A2/en not_active Ceased
- 2005-04-15 AT AT05779948T patent/ATE512365T1/de not_active IP Right Cessation
- 2005-04-15 ES ES05779948T patent/ES2367311T3/es not_active Expired - Lifetime
- 2005-04-15 US US11/106,932 patent/US7456027B2/en not_active Expired - Lifetime
- 2005-04-15 CA CA2578680A patent/CA2578680C/en not_active Expired - Lifetime
- 2005-04-15 EP EP05779948A patent/EP1747282B1/de not_active Expired - Lifetime
- 2005-04-15 AU AU2005245785A patent/AU2005245785B2/en not_active Ceased
- 2005-04-15 JP JP2007508611A patent/JP4885122B2/ja not_active Expired - Fee Related
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2008
- 2008-06-11 US US12/137,156 patent/US8298835B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2578680A1 (en) | 2005-12-01 |
| US7456027B2 (en) | 2008-11-25 |
| EP1747282A4 (de) | 2009-11-11 |
| AU2005245785B2 (en) | 2011-04-07 |
| EP1747282B1 (de) | 2011-06-08 |
| WO2005113798A3 (en) | 2008-10-23 |
| CA2578680C (en) | 2011-06-14 |
| AU2005245785A1 (en) | 2005-12-01 |
| AU2005245785A2 (en) | 2005-12-01 |
| US20090317805A1 (en) | 2009-12-24 |
| EP1747282A2 (de) | 2007-01-31 |
| JP4885122B2 (ja) | 2012-02-29 |
| WO2005113798A2 (en) | 2005-12-01 |
| ES2367311T3 (es) | 2011-11-02 |
| US8298835B2 (en) | 2012-10-30 |
| JP2007535318A (ja) | 2007-12-06 |
| US20050260697A1 (en) | 2005-11-24 |
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