ATE513568T1 - Stickstoffoxidbeschichtungen für medizinische vorrichtungen - Google Patents

Stickstoffoxidbeschichtungen für medizinische vorrichtungen

Info

Publication number
ATE513568T1
ATE513568T1 AT06786300T AT06786300T ATE513568T1 AT E513568 T1 ATE513568 T1 AT E513568T1 AT 06786300 T AT06786300 T AT 06786300T AT 06786300 T AT06786300 T AT 06786300T AT E513568 T1 ATE513568 T1 AT E513568T1
Authority
AT
Austria
Prior art keywords
medical devices
nitrogen oxide
oxide coatings
coatings
coating
Prior art date
Application number
AT06786300T
Other languages
English (en)
Inventor
Scott I Merz
Melissa Reynolds
Mark E Meyerhoff
Himabindu Nandivada
Sangyeul Hwang
Joerg Lahann
Original Assignee
Accord Biomaterials Inc
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accord Biomaterials Inc, Univ Michigan filed Critical Accord Biomaterials Inc
Application granted granted Critical
Publication of ATE513568T1 publication Critical patent/ATE513568T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/114Nitric oxide, i.e. NO
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AT06786300T 2005-06-30 2006-06-30 Stickstoffoxidbeschichtungen für medizinische vorrichtungen ATE513568T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69526705P 2005-06-30 2005-06-30
PCT/US2006/026101 WO2007005910A2 (en) 2005-06-30 2006-06-30 Nitric oxide coatings for medical devices

Publications (1)

Publication Number Publication Date
ATE513568T1 true ATE513568T1 (de) 2011-07-15

Family

ID=37605167

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06786300T ATE513568T1 (de) 2005-06-30 2006-06-30 Stickstoffoxidbeschichtungen für medizinische vorrichtungen

Country Status (6)

Country Link
US (1) US20090118819A1 (de)
EP (1) EP1896091B1 (de)
JP (1) JP2008544820A (de)
AT (1) ATE513568T1 (de)
CA (1) CA2613108A1 (de)
WO (1) WO2007005910A2 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
WO2005067986A1 (en) 2004-01-07 2005-07-28 Noxilizer, Inc. Sterilization system and device
US8017074B2 (en) 2004-01-07 2011-09-13 Noxilizer, Inc. Sterilization system and device
EP1888510A4 (de) 2005-05-27 2013-01-16 Univ North Carolina Stickoxidfreisetzende partikel für stickoxidtherapeutika und biomedizinische anwendungen
US20080241208A1 (en) * 2005-06-30 2008-10-02 Charles Shanley Methods, Compositions and Devices For Promoting Anglogenesis
JP2009518069A (ja) * 2005-12-02 2009-05-07 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン 組成物、コーティング及びデバイス、並びにそれらの製造方法及び使用方法
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070196428A1 (en) * 2006-02-17 2007-08-23 Thierry Glauser Nitric oxide generating medical devices
US7909928B2 (en) * 2006-03-24 2011-03-22 The Regents Of The University Of Michigan Reactive coatings for regioselective surface modification
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US7947148B2 (en) 2006-06-01 2011-05-24 The Regents Of The University Of Michigan Dry adhesion bonding
EP2054537A2 (de) 2006-08-02 2009-05-06 Boston Scientific Scimed, Inc. Endoprothese mit dreidimensionaler desintegrationssteuerung
JP2010503494A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生分解性内部人工器官およびその製造方法
CA2663250A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
EP2121068B1 (de) * 2006-09-15 2010-12-08 Boston Scientific Scimed, Inc. Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten
EP2959925B1 (de) 2006-09-15 2018-08-29 Boston Scientific Limited Medizinische vorrichtungen und verfahren zu ihrer herstellung
US8002821B2 (en) 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
CA2674195A1 (en) 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
US8399047B2 (en) * 2007-03-22 2013-03-19 The Regents Of The Univeristy Of Michigan Multifunctional CVD coatings
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
WO2010022132A2 (en) * 2008-08-19 2010-02-25 The Regents Of The University Of Michigan Biocompatible coatings, and methods of making and using the same
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
EP2517736B1 (de) 2009-02-23 2014-03-26 Noxilizer, Inc. Vorrichtung zur Gassterilisation
US8267992B2 (en) 2009-03-02 2012-09-18 Boston Scientific Scimed, Inc. Self-buffering medical implants
JP5205509B2 (ja) * 2009-03-06 2013-06-05 テルモ株式会社 血管留置デバイス、これを用いた血管狭窄モデルおよびその作製方法
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
BR112012003804B1 (pt) 2009-08-21 2019-02-19 Novan, Inc. Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento
US8771756B2 (en) 2009-12-28 2014-07-08 Colorado State University Research Foundation Biocompatible materials for medical devices
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
ES2695173T3 (es) 2011-02-28 2019-01-02 Novan Inc Partículas de sílice modificadas con S-nitrosotiol que liberan óxido nítrico y procedimientos de fabricación de las mismas
ES2821658T3 (es) * 2013-03-13 2021-04-27 Noveome Biotherapeutics Inc Dispositivo médico que tiene un revestimiento que comprende ACCS
US9901663B2 (en) 2013-05-06 2018-02-27 Abbott Cardiovascular Systems Inc. Hollow stent filled with a therapeutic agent formulation
CN104673096B (zh) 2014-08-12 2017-05-17 西南交通大学 一种具有一氧化氮(no)催化活性的涂层的制备方法
US11883807B2 (en) 2017-04-11 2024-01-30 Colorado State University Research Foundation Functionalization of metal-organic frameworks
WO2018226334A1 (en) * 2017-06-06 2018-12-13 St. Jude Medical, Cardiology Division, Inc. Electrophysiology Device with Ion-Selective Electrodes
WO2019014348A1 (en) 2017-07-11 2019-01-17 Colorado State University Research Foundation CHITOSAN COMPOSITE MATERIAL AND METALLO-ORGANIC STRUCTURE
WO2020018488A1 (en) * 2018-07-16 2020-01-23 University Of Georgia Research Foundation, Inc. Robust nitric oxide-releasing polymers and articles and methods of making and uses thereof
US20210386944A1 (en) * 2018-10-12 2021-12-16 Sanotize Research Development Corp. Gas-evolving compositions and container and delivery systems
US11986597B2 (en) * 2019-08-23 2024-05-21 NOTA Laboratories, LLC Nitric oxide generating systems for inhalation
CN114129780B (zh) * 2020-09-03 2022-06-28 天津大学 一种光控释放一氧化氮的复合水凝胶的制备及应用
US20240269353A1 (en) * 2021-05-21 2024-08-15 Know Bio, Llc Nitric oxide-releasing devices
WO2026006722A1 (en) 2024-06-28 2026-01-02 The Regents Of The University Of Michigan Nitric oxide generating medical devices and methods
CN119139562B (zh) * 2024-11-21 2025-03-07 四川大学 一种硫化氢/一氧化氮协同抗炎抗凝促修复涂层及其制备方法和应用

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959135A (en) * 1987-02-25 1990-09-25 Aquanautics Corporation Polyalkylamine complexes for ligand extraction and generation
US4952289A (en) * 1988-05-09 1990-08-28 Aquanautics Corporation Macrocyclic amine complexes for ligand extraction and generation
US5155137A (en) * 1990-09-20 1992-10-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complexes of nitric oxide with polyamines
US5389675A (en) * 1992-03-27 1995-02-14 The United States Of America As Represented By The Department Of Health And Human Services Mixed ligand metal complexes of nitric oxide-nucleophile adducts useful as cardiovascular agents
US5814666A (en) * 1992-04-13 1998-09-29 The United States As Represented By The Department Of Health And Human Services Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents
US5525357A (en) * 1992-08-24 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US5405919A (en) * 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
US5650447A (en) * 1992-08-24 1997-07-22 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nitric oxide-releasing polymers to treat restenosis and related disorders
US5632981A (en) * 1992-08-24 1997-05-27 The United States Of America As Represented By The Department Of Health And Human Services Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US6087479A (en) * 1993-09-17 2000-07-11 Nitromed, Inc. Localized use of nitric oxide-adducts to prevent internal tissue damage
CA2173738A1 (en) * 1993-10-08 1995-04-20 James B. Mitchell Use of nitric oxide-releasing compounds as hypoxic cell radiation sensitizers
US5840759A (en) * 1993-10-08 1998-11-24 The United States Of America As Represented By The Department Of Health And Human Services Use of nitric oxide releasing compounds to protect noncancerous cells from chemotherapeutic agents
US6747062B2 (en) * 1994-09-26 2004-06-08 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Regulation of wound healing by nitric oxide
US5714511A (en) * 1995-07-31 1998-02-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organs
US6232434B1 (en) * 1996-08-02 2001-05-15 Duke University Medical Center Polymers for delivering nitric oxide in vivo
US5797887A (en) * 1996-08-27 1998-08-25 Novovasc Llc Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation
CA2294872A1 (en) * 1997-06-24 1998-12-30 Schering Aktiengesellschaft Stents that are coated with fluoroalkyl groups, processes for their production and their use for restenosis prophylaxis
US5972338A (en) * 1997-09-19 1999-10-26 Genentech, Inc. Tie ligands homologues
US5994444A (en) * 1997-10-16 1999-11-30 Medtronic, Inc. Polymeric material that releases nitric oxide
US6119028A (en) * 1997-10-20 2000-09-12 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces
US6379691B1 (en) * 1998-09-29 2002-04-30 Medtronic/Ave, Inc. Uses for medical devices having a lubricious, nitric oxide-releasing coating
US6299980B1 (en) * 1998-09-29 2001-10-09 Medtronic Ave, Inc. One step lubricious coating
US6636652B1 (en) * 1999-08-02 2003-10-21 The Regents Of The University Of Michigan Optical sensors for the detection of nitric oxide
WO2001010344A1 (en) 1999-08-04 2001-02-15 C.R. Bard, Inc. Nitric oxide releasing medical devices
US6737447B1 (en) 1999-10-08 2004-05-18 The University Of Akron Nitric oxide-modified linear poly(ethylenimine) fibers and uses thereof
US6270779B1 (en) 2000-05-10 2001-08-07 United States Of America Nitric oxide-releasing metallic medical devices
US6403788B1 (en) * 2000-07-11 2002-06-11 Eukarion, Inc. Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species
KR20030045847A (ko) * 2000-10-31 2003-06-11 쿡 인코포레이티드 코팅된 이식형 의료 장치
US6780849B2 (en) * 2000-12-21 2004-08-24 Scimed Life Systems, Inc. Lipid-based nitric oxide donors
CA2433803A1 (en) * 2001-01-16 2002-07-25 Mark E. Meyerhoff Biocatalytic and biomimetic generation of nitric oxide in situ at substrate/blood interfaces
US7128904B2 (en) 2001-01-16 2006-10-31 The Regents Of The University Of Michigan Material containing metal ion ligand complex producing nitric oxide in contact with blood
US7335383B2 (en) * 2001-01-16 2008-02-26 The Regents Of The University Of Michigan Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood
US6706274B2 (en) * 2001-01-18 2004-03-16 Scimed Life Systems, Inc. Differential delivery of nitric oxide
US7048939B2 (en) * 2001-04-20 2006-05-23 The Board Of Trustees Of The Leland Stanford Junior University Methods for the inhibition of neointima formation
US6660034B1 (en) * 2001-04-30 2003-12-09 Advanced Cardiovascular Systems, Inc. Stent for increasing blood flow to ischemic tissues and a method of using the same
US6977138B2 (en) * 2001-07-24 2005-12-20 Massachusetts Institute Of Technology Reactive polymer coatings
US6841166B1 (en) * 2001-08-21 2005-01-11 The Regents Of The University Of Michigan Nitric oxide-releasing polymers incorporating diazeniumdiolated silane derivatives
US7105175B2 (en) * 2002-06-19 2006-09-12 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
EP1545798A4 (de) 2002-08-02 2006-06-14 Us Gov Health & Human Serv Vernetzte stickstoffoxid freisetzende polyaminbeschichtete substrate, diese enthaltenden zusammensetzungen und herstellungsverfahren daf r
US20050008676A1 (en) * 2002-12-19 2005-01-13 Yongxing Qiu Medical devices having antimicrobial coatings thereon
AU2004249233A1 (en) * 2003-06-19 2004-12-29 Vascular Therapies Llc Medical devices and methods for regulating the tissue response to vascular closure devices
US20050033417A1 (en) * 2003-07-31 2005-02-10 John Borges Coating for controlled release of a therapeutic agent
US20050033263A1 (en) * 2003-08-07 2005-02-10 Medtronic-Minimed, Inc. System and method for restenosis mitigation
US20060008529A1 (en) * 2004-07-12 2006-01-12 Meyerhoff Mark E Use of additive sites to control nitric oxide release from nitric oxide donors contained within polymers
US20060039950A1 (en) * 2004-08-23 2006-02-23 Zhengrong Zhou Multi-functional biocompatible coatings for intravascular devices
AU2005289414B2 (en) 2004-09-27 2010-12-09 Government Of The United States Of America, Represented By The Secretary Department Of Health And Human Services Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof
WO2007005759A2 (en) * 2005-06-30 2007-01-11 Mc3, Inc. Analyte sensors and compositions for use therein
US20080241208A1 (en) * 2005-06-30 2008-10-02 Charles Shanley Methods, Compositions and Devices For Promoting Anglogenesis

Also Published As

Publication number Publication date
EP1896091B1 (de) 2011-06-22
EP1896091A2 (de) 2008-03-12
WO2007005910A3 (en) 2007-08-23
WO2007005910A2 (en) 2007-01-11
US20090118819A1 (en) 2009-05-07
CA2613108A1 (en) 2007-01-11
JP2008544820A (ja) 2008-12-11

Similar Documents

Publication Publication Date Title
ATE513568T1 (de) Stickstoffoxidbeschichtungen für medizinische vorrichtungen
ATE485849T1 (de) Polymerzusammensetzungen, überzüge und vorrichtungen und herstellungs- und anwendungsverfahren damit
WO2007117838A3 (en) Atomic layer deposition coatings for implantable medical devices
DE502008003302D1 (de) Kohlenstoffnanoröhrchenpulver, kohlenstoffnanoröhrchen und verfahren zu ihrer herstellung
ATE407982T1 (de) Metalleffektpigmente mit anorganisch/organischer mischschicht, verfahren zur herstellung solcher metalleffektpigmente und deren verwendung
WO2008033167A3 (en) Nano-particle biochip substrates
WO2007001803A3 (en) Cure catalyst, composition, electronic device and associated method
DE60327539D1 (de) Fluorpolymerbeschichtungen für implantierbare medizinische vorrichtungen
WO2008088507A3 (en) Blood-contacting medical devices for the release of nitric oxide and anti-restenotic agents
WO2007030266A3 (en) Nitric oxide-releasing polymers derived from modified polyimines
ATE457022T1 (de) Verbindungen für organische elektronische vorrichtungen
ATE460135T1 (de) Beschichtungen zur verwendung auf medizinprodukten
DE602006008814D1 (de) Polymerüberzug für medizinische vorrichtungen
WO2010039897A3 (en) Nanocrystals with functional ligands
WO2009076572A3 (en) Methods of making an article and articles
WO2008157570A3 (en) Device and method for restoration of the condition of blood
ATE523539T1 (de) Fluorchemische urethan-silan-verbindungen und wässrige zusammensetzungen davon
ATE383177T1 (de) Gleitüberzug für medizinprodukt
WO2010011407A3 (en) Methods of generating patterned soft substrates and uses thereof
TW200738449A (en) Metallic laminate and method for preparing the same
BRPI0717822A2 (pt) Composto, processo de fabricação de composto da fórmula i, composição farmacêutica, método de tratamento e/ou profilaxia de doenças que são associadas à modulação de receptores de cb2 e uso de composto.
EA200601804A1 (ru) Композиция для нанесения покрытия, изделие с нанесенным покрытием и способ его производства
WO2006063176A3 (en) Inhibition of biofilm formation using bacteriophage
WO2011031857A3 (en) Substrate surface modification utilizing a densified fluid and a surface modifier
ATE523572T1 (de) Fluorchemische urethanverbindungen und damit hergestellte wässrige zusammensetzung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties